摘要:

A gas jointer developed dermatitis from epoxy resin of Bisphenol A type. This substance penetrates plastic and rubber gloves. The man was compelled to change his job. There is a need for new types of gloves which are impermeable. The wearing of the existing types of glove by those not sensitised may be worthwhile because it probably lessens the dose of allergen absorbed and hence lessens the incidence of sensitisation.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04879.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Captafol is a common cause of dermatitis amongst workers in the timber industry. In a survey of 14 timber treatment plants 23 % of 133 workers exposed to captafol gave a history suggestive of occupationally induced dermatitis. Although allergic dermatitis can occur, irritant dermatitis is far more common. Attention to plant and personal hygiene will reduce the prevalence of captafol dermatitis significantly, Recommendations on how to achieve this are made.“The ultimate end… is not knowledge, but action. To be half right on time may be more important than to obtain the whole truth too late,” (Arist

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04880.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

The sensitization capacity of ethylenediamine was examined by the guinea pig maximization test and compared with dinitrochlorobenzene. Ethylenediamine was found to be a potent sensitizer.An attempt at oral induction of unresponsiveness (tolerance) was unsuccessful with ethylendiamine and DNCB and the same negative result was obtained with intravenous injection of ethylenediamine. Only by the intravenous injection of dinitrobenzene sulfonic acid was unresponsiveness successfully established in 90 % of the guinea pigs.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04881.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Twenty‐three patients suffering from pigmented contact dermatitis caused by cosmetics containing Brilliant Lake Red R were observed. Commercial samples of Brilliant Lake Red R proved to contain many ethyl acetate extractable impurities; 1‐phenylazo‐2‐naphthol and azobenzene were isolated and identified.To determine the responsible allergens, five patients were examined by patch tests with purified samples of azo‐dyes and the unidentified fractions of ethyl acetate extractable impurities. Three out of five showed weaker reactions to purified samples of Brilliant Lake Red R and the other two showed equal reactions compared to the commercial product.1‐Phenylazo‐2‐naphthol was found to be a strong allergen in all cases but none showed a positive reaction to azobenzene. Some unidentified fractions also gave positive results.Patch tests were performed with 4‐phenylazo‐1‐naphthol, 4‐phenylazo‐1‐naphthol‐2‐carboxylic acid, and 2,4‐bis(phenylazo)‐1‐naphthol, as structurally related compounds derived from 1‐naphthol. All gave negative and they were not detected in the ethyl acetate extractable

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04882.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

The effect of three industrial hand cleansers on transepidermal water loss (TWL) was evaluated in groups of healthy volunteers. After 2 weeks, subjects using Baracaide averaged 47 % less TWL than those using Swarfega und 35 % less than with Go‐Jo. In a second study in printers, the use of Baracaide decreased TWL by 20 % after 2 weeks. Because it contains no volatile solvents, Baracaide may be less injurious to the barrier laye

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04883.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Oil of turpentine has become an infrequent allergen because of its replacement by the petroleum product white spirit, its deliberate exclusion from industrial products, and because the balsam oils used nowadays do not contain the sensitiser Δ3‐carene. On the basis of the generally low incidence of sensitisation being currently recorded, the International Contact Dermatitis Group recommend that oil of turpentine be removed from standard patch test seri

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04884.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Healthy volunteers without nickel hypersensitivity were given 5.6 mg nickel orally. The nickel concentration was assayed in urine, serum and saune‐provocated sweat from hands and trunk before and after nickel ingestion. The nickel concentration in serum increased in all subjects, and in most cases in urine, but not decisively in swea

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04885.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

In the National Spinal Injuries Unit at Stoke Mandeville Hospital, rubber condom urinals, kept on the penis with a medical adhesive, are used for incontinent male patients where possible. However, contact allergy to rubber condoms and/or the adhesives is a common problem and can cause considerable morbidity in paralysed patients. This paper investigates the rubber chemicals and adhesives most commonly implicated in causing contact allergy. The survey was divided into two parts:1Patch testing symptomatic inpatients2A questionnaire sent to new patients from January 1974 to ascertain the overall incidence of contact allergy.It was found that allergy to mercaptobenzthiazole (MBT)‐ and thiuram‐containing condoms was relatively common and that latex/petroleum tube medical adhesives most commonly caused adhesive allergy. It is suggested that a condom made of the least allergenic: rubber and an adhesive causing the least number of allergic reactions should be used from the outset for paralysed patients requiring a condom uri

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04886.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

While participating in a clinical trial of suprofen, a new antiphlogistic agent, a 32‐year‐old atopic woman developed a severe contact dermatitis reaction of the hands to this substance. To check for cross‐reactivity patterns, patch tests were performed with similar arylalcanoic acid derivatives. Positive reactions were obtained for ibuprofen, ketoprofen, fenoprofen, naproxen, alclofenac, and metiazinic acid, which are all antiphlogistic and anti‐inflammatory agents for systemic use, and chlorambucil, which is an antineoplastic agent. The antigenic determinant seems to correspond to a very well‐defined structure: the carboxyl group (‐COOH) has to be separated from the aryl structure by at least one C atom (substituted or not). Furthermore, the aryl group must be substituted with different chemical groups but not in the ort

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04887.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04888.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY