ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04902.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

A nickel‐sensitized female patient developed a contact dermatitis reaction to her mascara that was maintained by her spectacle frames, which contained nickel. On patch testing, she reacted to dihydroabietyl alcohol (Abitol°). Which was present in her mascara, and hypoallergenic adhesive tape containing methyl abietate. There was also cross‐reactivity with colophony and abietic

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04903.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Two female patients with stasis dermatitis developed allergic contact dermatitis to hydro‐cortisone 17‐butyrale cream. Patch tests with hydrocortisone 17‐butyrate were positive, hut not with the vehicle. One patient was also allergic to two other commercial cortico‐steroids, but patch tests, revealed positive reactions only to ingredients or the vehicles.Attention is drawn to the frequency of contact allergy to corticosteroids in patients with stasis der

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04904.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

An attempt ha been made to determine the adsorption ability of surfactants by the human horny layersin vivo.For this purpose, a technique utilizing an acidic dye such as indigo carmine was applicable and convenient. Ourin vivostudy estimating adsorbing residual amounts of surfactants has revealed that there is a positive correlation between adsorbing and roughening effects. It is suggested that the pathogenesis of hand roughness is primarily related to the cumulative injury of the stratum corenum by adsorbing residual surfactant molecules.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04905.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Our patient was a 24‐year‐old female textile cutter who had a conjunctivitis and an erythematous itching Dermatitis of the eyelids, nasal mucous membranes, and the corners of the mouth. The patch tests with the standard standard series and a pharmaceutical test batten' were negative. Further epicutaneous testing revealed a strong positive reaction to the textile cutting patterns she handled, which were duplicated by diazo processing. Specifically, the contact dermatitis reaction was caused by dimethylthiourea an additive in diazo‐sensitized

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04906.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Sixteen patients with negative routine patch tests were challenged orally in a controlled trial with 2.5 mg nickel, I nig cobalt, and 2.5 nig chromium given as salts of the respective metals. All of the patients had symmetrical, vesicular hand dermatitis and in some cases also foot involvement. The dermatitis of two patients flared after challenge with cobalt; in two patients flare occurred following chromate ingestion.Prior to the oral challenge all the patients were patch tested with nickel sulphate, cobalt. chloride and potassium dichromate after adhesive tape stripping. Solutions of the same metal salts were used for intradermal testing. The intradermal test sites were read after 20 minutes and 48 hours, the patch tests, after 4Nh. Skin test reactivity correlated poorly to the results of the oral challenge, possibly due to nonspecific skin test reactivity.It is concluded that oral challenge is it valuable adjunctive diagnostic procedure in patients with pompholyx. Who have negative routine patch tests.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04907.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

To better understand the cutaneous react reactivity of vulvar skin, two chemical irritants were applied topically to 21 subjects. The forearm of each subject served as a comparative control. Test sites remained upon and were read at 24 hours. A significantly increased response to the irritants was noted on the vulvar skin.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04908.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Five albino rabbits were immunized every 2 weeks by intradermal injections of a nickel rabbit‐albumin complex and during alternate weeks by occluded cutaneous applications of 5% nickel sulphate in petrolatum. After 6 weeks of immunization, passive immunodiffusion disclosed precipitating antibodies against the nickel‐albumin complex in the serum of all the rabbits. The specificity of these antibodies was substantiated by the precipitation of anti‐albumin antibodies with rabbit albumin prior to immunodiffusion.Passive immunodiffusion was used to examine serum from 14 nickel‐sensitive patients for precipitating antibodies against a nickel human‐albumin complex. Five of the patients had widespread erythematous, nun‐eczematous reactions following oral challenge with 2.5 mg nickel us nickel sulphate, while five others suffered an aggravation of their nickel dermatitis. Precipitating antibodies were found in three patients, all of whom had experienced rapid‐onset erythema after oral challenge. A weak precipitate was seen in one of nine controls. The specificity of the precipitates was substantiated by reproducibility and by negative immunodiffusion after precipitation in the positive sera wit

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04909.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade, It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equal in any decade.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04910.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

For two years the employees in a Danish post office complained of irritation of the eyes and the skin. The symptoms were of varying intensity and disappeared during absence from work. A photocopying machine using wet toner proved to he the cause of the symptoms. It has not been possible to ascribe the symptoms to specific chemicals.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1979.tb04911.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY