摘要:

In Salvador, Brazil, 536 patients were patch tested with 24 contact allergens. The most common sensitizers included potassium dichromate, thimerosal, hydroquinone, nitrofurazone ointment and nickel sulfate. The results of this South American study are compared with those published by North American and European dermatologists. Low frequencies of positive reactions were encountered in Salvador to some substances, including mercury bichloride andp‐phenylenediamine. The influences of climate and life style in determining patterns of contact sensitivity are discusse

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03786.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

In a pharmaceutical industry, several cases of allergic contact eczema caused by the β‐adrenergic blocking agent alprenolol (Aptin) have appeared. This report deals with 12 men and two women who developed eczema during work with the substance. In 13 of the 14 cases, the induction time for sensitization was less than 1 year. The skin reactions were very florid. After healing they could be reproduced by very small quantities of the substance. In one case, eczema could also be produced after ingestion of Aptin tablets. AH the cases were transferred to other work within the factory. An intensive programme was implemented to remove dust from the working areas. Despite this, isolated new cases still appear.Some employees in contact with the substance also experienced mucous membrane symptoms. These symptoms could not be shown to have an allergic aetiology, but were considered to be irritant reactions. Alprenolol must be considered a very strong contact allerg

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03787.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Toothpaste flavors are fragrance mixtures. Oil of peppermint and spearmint, carvone and anethole are ingredients with a low sensitizing potential, but they are used in almost every brand of toothpaste and caused seven cases of contact allergy in a 6‐year period at Gentofte Hospital. Toothpaste reactions are rare due to several reasons; local factors in the mouth, the low sensitizing potential of the flavors generally used, and the lack of recognition. It is emphasized that the toothpaste battery for patch testing has to be relevant and changed according to the consumers' and manufacturers' taste and fashio

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03788.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Persons suffering from allergic dermatitis caused by direct contact withParthenium hysterophorus(Compositae) showed delayed immunologic reaction to the sesquiterpene lactone parthenin but not to its diasteriomer, hymenin.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03789.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

2.6‐dimethoxy‐1,4‐benzixjuinone has already been discovered in more than 25 different plants and woods. Several authors have shown its strong bacteriostatic activity against micro‐organisms.In 1972 a positive skin reaction to 2.6‐dimethoxybenzoquinone was obtained in a patient allergic to Sucupira wood (Bowdichia nitidaBenth.). This compound could be isolated from the wood.During the chemical investigations of other commercial woods which have been described as the cause of allergic contact dermatitis, 2.6‐dimethoxybenzoquinone could be isolated from an additional 21 different species. In the case of Australian blackwoodAcacia melanoxylonR. BR., its structure was elucidated by x‐ray analysis.Sensitization of guinea pigs revealed that 2.6‐dimethoxybenzoquinone is a relatively good sensitizer.In some of the woods investigated, quinones have never been discovered before, for example in Makoré, Australian blackwood, Wengé, White wood, Afrormosia and Afzelia. In 10 of them only this quinone was detectable.Besides its allergenic properties, 2.6‐dimethoxybenzoquinone may be responsible for the high termite resistance of these woods.In all cases of contact dermatitis from these wood species in which quinoid allergens other than 2.6‐dimethoxybenzoquinone could be detected, this quinone should be

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03790.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Two patients showed occupational contact sensitization to a component present in the Nyloprint photopolymer printing plate. The component could not be identified chemically. It contains an acrylamide group. Both patients gave group‐specific reactions to NN' methylene bis acrylamide. This must be a closely related substance. Possible preventive measures are discussed. The manufacturer should have disclosed the allergic substance and instructed his customer adequately. A “philosophy” concerning this point is being deve

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03791.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Two cases with allergic contact dermatitis from chromate in green military uniform sweater and pants are described. Chemical analysis showed that water‐soluble chromate was released from a uniform even after repeated washing

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03792.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

A 59‐year‐old saleswoman of black hats presented with a severe purpuric eruption of the exposed areas of the face, neck and arms. Patch testing to paraphenylenediamine produced a purpuric test reaction. Similar eruptions have been reported due to N‐isopropyl‐N‐phenylparaphenylenediamine (IPPD), a rubber antioxidant. The patient had previous dermatitis underneath the elastic portions of her undergarments. It was determined that IPPD is added to elastic material used in some elastic trim on undergarments in the United States. This relationship is

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03793.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03794.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1978.tb03795.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY