摘要:

A clinical study was performed in 66 female patients with hand eczema and contact allergy to nickel. They were drawn from a basic material of 165 patients with nickel allergy in which hand eczema occurred in 86 cases (52 %). The hand eczema started at an average age of 32 years and ii had been preceded by a metal hypersensitivity for an average of 6 years. The eczema was found to the chronic with a mean duration up to the time of examination of 8 years. It was associated with secondary eruptions in half of the cases. The hand eczema showed a low degree of relevance with regard to dependance of occupation or vacation, as well as to exacerbation of the dermatitis after a direct contact with nickel‐coated objects. The clinical examination disclosed in 77 % a pompholyx, i.e. a symmetric vesicular eruption mainly located on the palms and volar aspects of fingers, and sides of fingers. The eczema often showed a periodic activity, with about 15 annual eruptions in the pompholyx cases. It is concluded that simple external contact with the metal can hardly explain the most common clinical pattern of the hand eczema in nickel allerg

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05353.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A provocation study was performed in twelve female patients with contact allergy to nickel and hand eczema of the pompholyx type. Intense handling of nickel‐contaminated metal objects did not induce any visible eczematous activity. Oral administration of nickel in a double‐blind test provoked an aggravation of the hand eczema in nine of the twelve patients, and in seven of the patients this was accompanied by secondary eruptions including outbreaks of earlier, healed eczema. The nickel dose given is probably in the upper limit of the presently known daily intake of the metal, but should be considered to be within the physiologic range. It is concluded that ingestion of small amounts of nickel may be of greater importance in maintaining the hand eczema than external contacts with the me

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05354.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A patient With perfume dermatitis was patch‐tested to 94 constituents of perfume and was found to have positive reactions to 12 components. An approach with regard to reducing the prevalence of perfume dermatitis is Suggeste

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05355.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

The number of patients with dermatitis from applied betamcthasone‐17‐valerate ointment, which incorporated hydrogenated lanolin, rapidly increased in Japan after 1971. On patch testing, the incidence of hypersensitivity to hydrogenated lanolin is significantly higher than to anhydrous lanolin at the 1% level, that is, 5.20% (26/502) with the former and 1.99% (10/502) with the latter, although sensitivity to both materials is significantly related at the 0.5% level.The possible explanations considered are that hydrogenated lanolin contains three main allergens: the first is a group of lanolin alcohols which are the common eczematogens in anhydrous lanolin; the second refers to the products of hydrogenation, composed of saturated, easily oxidized, organic substances of low molecular weight; and the third refers to traces of nickel, copper and chromium, as a result of contamination in the hydrogenation proc

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05356.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Under ordinary working conditions in which grinding fluids were used, the presence of nickel or chromates was not detectable by spot testing. Laboratory studies, however, indicate that nickel can be leached from the machined metals.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05357.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A study of 35 hairdressers with hand eczema was made daring an 18‐month period. A total of 29 were test‐positive to one or more substances in I lit standard series and/or to products from their working environment. 40% were allergic to nickel. The prevalence of personal atopy was higher in the nickel‐negative than in the nickel‐positive. Immunoglobulin E determination was not of assistance in attempts to differentiate between nickel‐positive and nickel‐negative hairdressers. In 72 % the eczema had started before the age of 25 and in 23 % after less than 1 year in the profession. The desire is expressed that all hair‐dressing products shall be labelled in respect of allergen contents, since 46 % of The hairdressers reacted to one or mor

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05358.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

From the large number of substances used in perfumes it is difficult and tedious to identify the allergen in a specific case of dermatitis. Many substances are both irritants and sensitizers. Based on personal experience, a list has been prepared of potential sensitizers, their concentrations and diluents suitable for patch testing.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05359.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Changes in the shoe industry have replaced some of the former allergens and introduced some new ones. In 45 cases of shoe contact dermatitis, the lack of response to known allergens inspired the authors to review present‐day industrial shoe manufacture. Two new resin allergens for shoe dermatitis have been found: dodecyl mercapthane and polyurethanes. The first is used in the plastics industry to arrest the polymerisation process. We suggest the possibility that a certain number of Neoprene sensitizations could be sensitizations to dodecyl mercapthane contained in it. The recommended solution for patch testing is: 0.1 % in toluo

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05360.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A case is presented of a confectioner with a chronic hand dermatitis and positive patch test reactions to cardamom and certain terpenoid compounds present in the dried ripe seeds of cardamom. Cardamom is a popular traditional flavouring agent for baked goods and confectionery. Dermatitis from skin exposure to cardamom has to the best of our knowledge not been reported. We report one case of allergic contact dermatitis to cardamom elicited by terpenes present in the seeds.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05361.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A way of adapting a treatment room for patch lest purposes is described.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1975.tb05362.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY