摘要:

Sixteen patients with verified light sensitivity to both UVB and UVA wavebands showed allergic reactions to various lichen plants (Parmeliaspp.,Hypogymniaspp.,Pseuodoverniaspp.,Cladoniaspp.,Platismatiaspp.,Physciaspp.,Umbilicariaspp. andCetrariaspp.). Among the aromatic lichen compounds, atranorin was observed to be the most frequently involved allergen but also several other isolated lichen acids were immunologically active: d‐usnic, evernic, stictic, fumarprotocetraric, lobaric, salazinic, diffractaic and physodic/physodalic acid. Several patients showed allergy to other plant substances from other sources such as seven different species from the Compositae family, alantolactone, balsam of Peru, colophony and wood tars. Sensitivity to known photosensitizers was observed in four patients. Aromatic lichen acids are UV‐absorbing substances and several are evidently able to photosensitive human s

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03911.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

A patient developed an exanthem after inhalation of mercury vapors. Clinically and histopathologically the exanthem resembled an erythema exudativum multiformelike drug eruption.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03912.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

A total of 132 patch tested patients reacted with petechial reactions to cobalt chloride 1 % in petrolatum; 23 were retested with various concentrations of cobalt. In about 60% of those retested the petechial reaction could be reproduced. Histopathological examination showed slight perivascular tymphocytic infiltration, swollen endothelium and extravasation of erythrocytes but no signs of vasculitis.It is suggested that in predisposed patients the petechial reaction following patch testing could be the result of primary irritation.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03913.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Allergic contact dermatitis due toPhilodendron scandensKOCH et SELLO subsp.oxycardium(SCHOTT) BUNTING (“Philodendron scandens cordatum”) is seldom reported. In four patients with dermatitis, allergy to philodendron species was found through parch testing with leaves, stems and ether extracts from eight philodendron species. Although this allergy appears to be rare, it ought to be considered in patients with dermatitis on hands, arms and f

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03914.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

During 1976–77 a field investigation was carried out into skin diseases among house painters in Stockholm, Sweden. The study was divided into three stages: I. questionnaire investigation, II. examination of painters who reported skin diseases, and III. patch testing and final classification. Of the 2,622 painters registered on 30 November 1976, 2239 (85.4 %) answered the questionnaire. Current dermatoses were reported by 373 painters (16.7 %) and of these, 227 were examined by us, 40 had recently been examined, and 106 did not attend. Occupational contact eczemas were diagnosed in 87 cases, and it was doubtful if the dermatoses were occupational in an additional 56 cases. A prevalence of 3.9 % was suggested, but this represents a minimum figure. Chloracetamide was found to be an important cause of occupational contact eczema. A personal and/or family history of atopy was common among the affected painters. Solvents were widely used for skin cleansing; there is a great need for continuous information on protective measurements, and on skin cleansing and care. It is concluded that field investigations give higher and probably more reliable prevalence figures for occupational dermatoses than data compiled from outpatient clinic

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03915.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

“Eau de Javel” (liquid bleach) is a common cause of chromate contact allergy. A historical review explains the reasons for the addition of sodium dichromate after the First World War. The chromium content in different brands of eau de Javel has been determined by flameless atomic absorption spectrophotometry. The results indicate that the chromium content is very low (0.03–3.65 mg/1) in French brands, whereas it is still important (7.06–82.9 mg/1) in Belgian brands; such an observation indicates that the almost complete removal of chromate in most brands of French eaux de Javel is a good example of prevention in the field of contact dermato‐al

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03916.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Atranorin, one of the most common lichen substances, gave positive patch test reactions in eight subjects (1 %) in a routine series. These subjects also reacted to fumarprotocetraric acid and some of them to evernic acid. Stictic acid and usnic acid gave negative reactions. The lichen oak mossEvernia prunastriand an oak moss perfume gave positive reactions. Thin‐layer chromatography and a spot test indicated that atranorin is present in oak moss perfumes which are made from oak moss and tree moss. Contact with oak moss perfumes and lichens in nature may cause atranorin allergy. None of the eight subjects had a history of light sensitivity or atopy and none had chronic facial eczem

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03917.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Acetylethyltetramethyltetralin, a widely used synthetic fragrance material, was found to cause neurotoxic effects in animals, 6‐Methylcoumarin, another fragrance material, was determined to be a photocontact allergen. Insufficient information on their usage, consumer exposure and likely hazard to human health under conditions of use impair regulatory decisions. FDA's ability to protect consumers against a health hazard is greatly influenced by the availability of such dat

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03918.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

All contact dermatitis patients are told to avoid their specific allergens. As regards topical pharmaceutical agents, however, it is almost impossible for these patients to identify the products that contain their allergens. In order to provide reliable information for these patients, we have designed a computer assisted data system, The CODEX (COntact DErmatitis indeX) system consists of three computer readable files: a Product File containing the complete composition of the pharmaceutical products an the Belgian market that arc applied on the skin and the mucous membranes, a Patient File with the patient's anamnesis, and a Literature File with cross‐referenced material on contact dermatitis. Each patient is given a list of the products that contain his/her allergen(s). The data bases are analyzed statistically and updated periodically. Cosmetics in general are exclude

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03919.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

A false negative patch test can be related to errors in the testing procedure, or to a defect in the eliciting (efferent) phase of the immune response. To define this phase the application of a topical irritant (a “positive control”) is suggested. Various concentrations of non‐anoic acid in 1‐propanol were applied to 116 healthy volunteers and to 75 dermatitis patients. Dose‐response curves were obtained (concentrations 5, 10, 20 and 39.9 %). Twenty percent nonanoic acid produced skin reactions in 90.1–93.9 % of the subjects. The lesions consisted mainly of erythema at 48 h and pigmentation at 96 h. We suggest that the most interesting patients are those negative to this primary irritant and that they should be furthe

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1980.tb03920.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY