摘要:

Deodorized kerosene in a concentration of 50g/100g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The response in a group of 40 animals, half exposed to tetraethyleneglycol diacrylate and half to nonylphenol polyethoxylate‐6, increased (z= 3.505,p=0.004). The inflammatory response was related to concentration in both groups of animals which exhibited inflammatory responses to deodorized kerosene. The relevance of this alteration and irritant response of the interpretation of predictive to tests animals for sensitization, routine patch testing and repeated insult contact dermatitis is discusse

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04459.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

A study of 12 patients with allergic contact sensitivity to ethylenediamine has shown that exposure to the oral antihistamine promethazine hydrochloride (Phenergan®) did not result in an exacerbation or recrudescence of eczema. This would suggest that promethazine may be safely administered to ethylenediamine‐sensitive patients contrary to advice given in some of the dermatological literatu

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04460.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

11 men developed a severe phototoxic dermatitis of the hands and forearms after harvesting celery infected withSclerotinia sclerotiorum.By thin‐layer chromatography and fluorescence spectrophotometry, xanthotoxin, bergapten and sphondin were isolate‐d. TheCanadida albicanstest demonstrated xanthotoxin and bergapten as the phototoxic compou

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04461.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

A woman who had ingested honeybee royal jelly as a nutrient, showed an exacerbation of dermatitis when it was applied to her feet. A topical fungicide also aggravated her skin lesions. Patch testing showed positive reactions to the royal jelly, pyrrolnitrin in the fungicide and urushiol. Positive reactions to the royal jelly were found in 2 out of 10 controls, 1 of whom was sensitive to propolis.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04462.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Allergic contact sensitivity to 5‐[(2‐aminoethyl)thiomethyl]‐N,N‐dimethyl‐2‐furanmethanamine, a diamino intermediate in the synthesis of a novel H2 antagonist, Ranitidine® is reported in an industrial chemist with hand dermatitis, who had been working for a prolonged period on the conversion of this intermediate to its f

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04463.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

3 chemically pure fractions were isolated from Napp® printing plate and subsequently identified by means of nuclear magnetic resonance, infrared spectrophotometry and elemental analysis. 1 of the fractions elicited positive test reactions in 3 Napp®‐allergic printers, and another fraction also elicited a positive test reaction in 1 of the printers. The 2 allergens were 2‐hydroxyethyl methacrylate and N.N′‐methylene‐bis‐acrylamide. The 1st of the 2 allergens was also demonstrated in another printing plate,

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04464.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

The dissemination of allergenic plants as horticultural introductions, or in the case of the weedParthenium hysterophorus L.apparently by chance, can have undesirable results. This species of the Compositae family, native to the Caribbean region, has spread widely in India, causing allergic contact dermatitis from its content of sesquiterpene lactones, and has recently appeared in Australia.The clinical features consist of dermatitis of the exposed skin surfaces from direct contact with the weed, but resembling photo dermatitis. In fact, contact dermatitis from the plant can coexist with light sensitivity. The plant does not show phototoxic activity but may contain an unidentified photo allergen. Since plant hairs and the pollen contain sesquiterpene lactones, they can probably cause air bone contact dermatitis. Attempts to control spread of the plant have so far not been successful.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04465.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

2 case reports are given of patients with positive patch test reactions to clobetasol propionate. One of the patients also reacted to clobetasone butyrate. 30 other steroids that were chemically very closely related to these two 2l‐chloro‐9‐α‐fluoro‐corticosteroids, were patch test negative. The literature on contact dermatitis reactions to corticosteroids i

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04466.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

The capacity tegobetain, pyrrolnitrin, tolcylate and chlorquinaldol to induce delayed‐type con tact sensitization was studied in guinea pigs in 2 series of tests using the method of Magnusson&Kligman and the authors’modification of the wholly intradermal Draize technique‐ Histological examination of skin biopsies obtained from the test area demonstrated that tegobetain, pyrrolnitrin and tocyclate are potential sensit

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04467.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Although one study has reported a cross‐reactivity between DNCB and chloramphenicol in 40% of patients, other investigators have been unable to confirm the existence of any cross reaction. The purpose of this study is to determine whether sensitization of patients to DNCB poses a risk of cross reaction to chloramphenicol. In the present study, 100 consecutive patients who were sensitized to DNCB failed to show a single reaction to patch testing with chloramphenicol in a 1% ointment. The discrepancy between these results may be explained by a possible misinterpretation of a primary irritant reaction as an allergic contact reaction in the original repor

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1983.tb04468.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY