摘要:

A simple micro‐computer program was used lo analyse the results of testing 501 consecutive patients of tending a patch test clinic. 64% of mules and 71% of females had positive tests; 17% of males and 12% of females had occupational dermatitis: 16% of males and 15% of females had irritant contact dermatitis; and 13% of males and 19% of females had a history of atopic eczem

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01310.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Grevillea‘Robyn Gordon’is an Australian hybrid plant which may cause allergic contact dermatitis. Over the past 8 years, in bag been planted extensively in Australia and is now being exported to the United Slates mid other Western countries. Recently, fin explosion in incidence of contact dermatitis due to this plant has been seen. 24 patients who were suspected of being sensitive to it were patch tested to fresh plant and extracts with confirmation of sensitivity.A cross sensitivity to Toxicodendron was demonstrated clinically and on patch testing. The allergen inToxicodendron, 3 pentadecylcatechol, is closely linked in chemical structure to 5‐penladecylresorcinol. present inGrevillea banksiiand tridecylresorcinol inGrevillea robusta.Patch letting in patients sensitive toGrevillea‘Robyn Gordon’with tridecylresorcinol produced positive reactions, thus implicating the sensitizing role of long chain alkyl resorcinols inGrevillea‘Robyn Gordon’allergy. There is a likelihood that (his sensitizing potential extends to other plants of theGrevilleagenus, e.g.Grevillea robusta.With the spread ofGrevillea‘Robyn Gordon’to other markets, this problem will become in

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01311.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Skin disorders were reported in 33% of catering staff mid>5% of women cleaners who returned a questionnaire, and were employed in a large hospital. Hand dermatitis occurred in 15% of the caterers and 12% of the cleaners. In the majority, the dermatitis was irritant in origin and related to their wet work occupations. Cleaners had a high prevalence of jewellery dermatitis. Limited patch testing revealed a majority positive to nickel, but a third were negative, indicating that jewellery reactions often but not invariably predict nickel sensitivity. Few subjects were atopic, hut some psoriatic patients with hand problems were encountered. Most workers were able to carry on in their Occupations despite having hand dermatitis.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01312.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

A retrospective study of patterns patch tested between 1968 and 1970 was undertaken and case records of 200 patients with unequivocal positive patch tests were studied for age and sex distribution. There was an overall female preponderance (61%). with 2 peaks of incidence in the 10–211 and 40–50 year age groups in females, but only 1 peak of incidence in the 40–50 year ape group in males. There was a steady decline in all sensitivities after the 6th decade of life in both sexes. Nickel sensitivity was more common in females (92%), whereas dichromate sensitivity predominated in males (64%). Of the 200 patients, only 5(2.5%). were atopics, all of whom were fe

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01313.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

2 patterns are reported with chronic hand dermatitis related lo sensitization to sodium hypochlorite, as the active component in a bleaching product. To avoid irritant reactions in patch testing, a sodium hypochlorite concentration of 1.0% appeared to be useful. It is concluded that with regard to the frequent use of bleaching agents, allergy to sodium hypochlorite must be considered in certain cases of unidentified chronic allergic hand dermatitis.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01314.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Irritant skin reactions from repeated open applications of low concentrations of sodium lauryl sulphate (SLS) have been studied microscopically and microscopically in guinea pigs. After 3 applications daily for 3 days. 2% SLS aqueous solutions gave a naked eye assessment, increase in epidermal thickness and total dermal inflammatory cell response, which was greater than for a 1% SLS solution. The dermal inflammatory cell response was mainly mononuclear (lymphocytic) in nature. With the SLS reactions as control, various organic solvents were studied and ranked against the SLS reactions and internally. Trichlorethylene was the most irritant solvent, ranking as high as 2% SLS Other chlorinated hydrocarbons and aromatic hydrocarbons tested caused irritant reactions. The alcohols and acetone gave no reaction. White spirit was us irritant as trichlorethylene. Thinners were less irritant, around the level of the 1% SLS control reaction. The 4‐day experimental design is a convenient and suitable animal model for screening irritant potential, and provides information relevant to the pathogenesis of irritant contact reactio

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01315.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

Glyphosate it widely utilized herbicide, was evaluated for acute irritation, cumulative irritation, photoirritation and allergic and photoallergic contact potential in 346 volunteers. The herbicide was less irritant than a standard liquid dishwashing detergent and a general all purpose cleaner. There was no evidence for the induction of photoirritation, allergic or photoirritation contact dermatitis. 10% glyphosate in water is proposed as a diagnostic path test concentration.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01316.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

10 coumarins used in perfumery, cosmetics and ointments, have been investigated by 2 different methods to determine their sensitizing capacity. Only I of the compounds, 4‐methyl‐esculctin, which serves as a sunscreen agent, was found to be a weak sensitizer. All other coumarins were negative. It is assumed that this dihydroxycoumarin becomes a sensitizer when it is enzymically oxidized to the corresponding orthoquinone in the s

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01317.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

A patient is presumed who developed chloracne after exposure to lumber which was pressure‐treated with pentachlorophenol (PCP) it was poisoned that his disease arose via percutaneous absorption of polychlorinated aromatic compounds (dioxins and furans) which are known to contaminate technical grade PCP The patient's condition improved after treatment with oral isotretinoi

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01318.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY

摘要:

The total cobalt and nickel concentration of 11 brands or Asian cement ranged from 8.1 to 14.2 μg/g and 28.5 μg/g, respectively. These metals exist mainly as insoluble suits; the water‐soluble concentration of cobalt and nickel in the cements ranged from 039 to 0.65 μg/g and from 0–1.2 μg/g. respectively.1.5% (4/272) of construction workers in a prefabrication construction factory had cobalt sensitivity. All had allergic contact dermatitis from chromate in cement. No worker and isolated cobalt sensitivity and cement dermatitis. It appeared that sensitization to cobalt in cement occurs only Secondarily to an existing cement dermatitis 1.8% (5/272) workers had nickel sensitivity: 2 with allergic contact dermatitis to nickel in their watches. 2 were asymptomatic and I had allergic contact dermatitis to chromate and cobalt in content. The low prevalence of cobalt and nickel sensitivity from cement was probably related to the low concentration of soluble cobalt and nickel salts in the cement. However, these insoluble salts can form soluble completes with body fluids on eczematous skin and sensitize t

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1986.tb01319.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY