摘要:

Using a standardized open photopatch test technique, the phototoxic reactions produced by bergamot oil bergapten (5‐methoxypsoralen) the active component of the oil, and xantho‐toxin 8‐methoxypsoralen) were studied. The reaction was affected by a range of factors such as the vehicle (PMF or ethanol), the concentration of ethanol in the vehicle, the skin site, the interval between application of the psoralen and irradiation, the hydration of the skin, and the degree of natural or sun‐induced pigmentation. Repented photopatch testing at the same skin site produced an increase in sensitivity.Eye colour, natural susceptibility to suntanning, age, and sex, had no effect on the phototoxic response to ps

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03667.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Positive patch test reactions to isopropyl alcohol in connection with proved allergy to ethyl alcohol have already been published. A case of allergy to isopropyl alcohol with positive reactions to isopropanol (unpurified test material) and negative reactions to ethonol) and methanol has also been reported. We report a case of a occupationally acquired sensitivity to isopropyl alcohol in which, or testing with gas chromatographically purified material, positive patch test reactions were found to 1‐propanol, 1‐butanol, 2‐propanol, 2‐butanol and methanal (formaldehyde) but not to the primary alcohols methanol, ethanol and amyl alcohol; not to the aldehydes acetal (acetaldehyde) and butanal; nor to the ketones acetone, butanon and isobutyl ketone, nor to methanoic (formic) acid. A tentative explanation for this peculiar pattern of reactions i

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03668.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Five out of 26 men employed formulating radiation drying printing ink developed eczematous dermatitis. Positive patch tests were obtained with two polyfunctional acrylic monomers, pentaerythritol triacrylate and trimethylol propane triacrylate and with formulations containing these in four affected employees. Cross sensitization was observed to dipentaerythritol monohydroxy pentaacrylate in each case. A fifth employee appeared to have developed irritant dermatitis from contact with these materials.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03669.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Patch tests and photopatch tests with Various cosmetics, coal tar dyes, perfumes, lanolin preparations and parabens‐mix were performed in 53 patients with pigmented cosmetic dermatitis similar in clinical appearance to Riehl's melanosis. The results showed that coal tar dyes, particularly brilliant lake red R, were closely related to the cause of the disease. In patch testing and photopatch testing with coal tar dyes, the incidence of positive responses to the brilliant lake red R was found to be significantly higher than that to the other coal tar colors (22/38 = 57.9 %). The relevance of ultraviolet light to the disease was found to be much less than the ratio expected (14/47 = 29.8%). A high incidence of positive responses to fragrances was also found, but it is considered to play a secondary role in the etiology of the diseas

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03670.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

The Letterflex urethane photopolymer mixture contains eight components. The curing agent penta erythritol‐tetrakis‐3 mercaptopropionate and an auxiliary subtance present separately, namely 3 mercaptopropionic acid, gave positive reactions in five patients suffering from occupational contact allergic dermatitis. The mixture contains third substance to which contact sensitization in n single patient has been described in the literature. This substance did not play any role in the patients dermatitis. The ways in which the workers come into contact with the liquid form of the prepolymer, which is the sensitizing form of the mixture, are described. Safety measures and complete labelling are advi

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03671.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Irritant reactions were induced on the forearms of 10 normal subjects with 10% aqueous sodium lauryl sulfate under patch test occlusion for 24 h. Test sites were observed at 24, 26, 28, 30, 48, 72 and 96 h and the degree of inflammation recorded. Inflammation was must prominent at 28 h and decreased in intensity over the time course of the study. Inflammation at 48 and 72 h was similar to when patches were removed. This suggests that inflammatory responses in skin for at least certain irritants like sodium lauryl sulfate do slowly decrease in intensity after 48 h. However, the inflammatory response may initially accelerate after patch test removal and remain intense for at least 48 h. Fading of irritant reactions by 48 or 72 h may not reliably distinguish irritant from allergic patch test, reactions. This does not refute the usefulness of a delayed (96 h) reading since inflammation from sodium lauryl sulfate had decreased significantly by this time.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03672.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Ten patients with a history of photosensitivity and of a rash showed abnormal reactions to long‐wave UVR. The rash occurred particularly in areas exposed to light, though other areas were occasionally involved. The development of the rash could in all patients be related to contact with lichens and although exposure to sunlight usually led to an aggravation of symptoms, some patients, particularly forestry workers, showed exacerbations even during the winter. Positive responses were observed in both irradiated and non‐irradiated patch tests with different species of lichen and in several patients irradiation precipitated a stronger response. These findings suggest that lichens can cause both contact and photocontact dermatitis. The suspected allergens contained in these lichens are atranorin, physodalic and pysodic ac

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03673.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Four formulations of benzoyl peroxide, two 5 % and two 10 % gels, were assayed for contact sensitizing capability by the human maximization test. Seventy‐six per cent became sensitized. Sensitized subjects reacted to all four formulations. Benzoic acid and related compounds failed to elicit an allergic reactio

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03674.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03675.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03677.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY