摘要:

AbstractObjective: To evaluate the clinical performance of gamete intrafallopian transfer (GIFT) andin vitrofertilization and embryo transfer (IVF‐ET).Methods: Infertile women were divided into 2 groups: for GIFT, 239 patients (326 cycles) with at least 1 patent tube; and, for IVF‐ET, 125 patients (210 cycles) with bilateral tubal occlusion. A specially designed retractor was developed to replace the gametes into an appropriate section of the Fallopian tube accurately and safely. Several parameters, including the pregnancy and delivery rates of each group, were compared.Results: The success rate per trial in the GIFT group was approximately 1.5 times higher than that in the IVF group (pregnancy rate: 44.2% vs. 31.0%, p<0.01; delivery rate: 33.4% vs. 22.9%, p<0.01). The pregnancy and delivery rates of GIFT decreased steadily with the number of trials. These apparent decreases were not observed up to the 3rd trial in IVF‐ET cases.Conclusions: GIFT with a minilaparotomy procedure yielded significantly higher success rates than IVF‐ET. Accordingly, GIFT is considered to be the first treatment choice in infertility cases with at least 1 patent Fallopi

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01049.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractObjective: The aim of this study was to determine the incidence of HbS and glucose‐6‐phosphate dehydrogenase (G6PD) deficiency in Jordanian newborn.Study Design: A total of 181 male and female babies born at Princess Basma Teaching Hospital, randomly selected, and cord blood samples were collected, and the erythrocyte G6PD activity was measured, and the hemoglobin electrophoresis for blood lysate was conducted and scanned for HbS scanning.Results: The frequencies of two major red cell genetic defects, sickle hemoglobin (HbS) and deficiency G6PD was determined, of the studied subjects 10 (11%) females and 11 (12%) males were found to be deficient in the G6PD gene. The frequency of HbS carriers among the females was 4% while it was 6% among males. The coincidence of both G6PD deficiency and sickle cell hemoglobin in the samples was 1%. No coincidence was found between G6PD deficiency and hyperbilirubinemia.Conclusion: A better understanding of the distributions of these genetic disorders has the potential to aid in the more efficient utilization of health care resources and improved plann

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01050.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractThe occurrence of pulmonary embolisms in patients having circulating lupus anticoagulant has been reported.1–3) Lupus anticoagulant has been noticed in association with autoimmune diseases1,4–6) and early‐onset severe preeclampsia.7–10) We report a case of Sjögren's syndrome with circulating lupus anticoagulant in a patient who developed a pulmonary embolism and severe preeclampsia at 29 weeks of g

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01051.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractIn a randomized controlled trial 201 healthy nulliparous women were randomly allocated by means of a computer generated randomization list. From 20 weeks of gestation until delivery they received either 2 g of oral elemental calcium (n= 103) per day or an identical placebo (n= 98). Eleven women (5.47%) were lost to follow‐up after randomization. The study groups were very similar at the time of randomization; with respect to several clinical and demographic variables. Treatment compliance was very similar in both groups as was determined by pill count.1The rate of pregnancy induced hypertension was lower in the calcium group than in the placebo group 8.24%; vs 29.03%; (RR = 0.28; 95% CI 0.14–0.59). The incidence of gestational hypertension was 6.18% in the calcium group and 17.20% in the placebo group (RR = 0.28; 95% CI 0.08–0.80), and the incidence of preeclampsia was 2.06% in the calcium group and 11.82% in the placebo group (RR = 0.13; 95% CI 0.01–0.64). In conclusion calcium supplementation given in pregnancy to nulliparous women reduces the incidence of pregnancy induced hyper

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01052.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractOnce a caesarean section always a caesarean section may not stand true any more but twice a caesarean section always a caesarean section still stays put because of its high maternal and foetal complications. Jinnah Postgraduate Medical Centre is large tertiary care hospital and has a caesarean section rate of over 18%; 10 patients (3.9%) were picked up in a retrospective study who had vaginal delivery after 2 previous caesarean sections in 2 years. They were admitted late in labour. Only one patient had dehiscence of scar. The aim of the study was to evaluate the outcome and safety of vaginal deliveries after 2 previous caesarean sections even when the trial was not conducted at the hospital.

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01053.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractA 55‐year‐old woman presented with vaginal bleeding. A tumor was found in the cervix; it was composed of 2 distinctive elements: a clear‐cell adenocarcinoma and a choriocarcinoma. Histologic findings suggested that the choriocarcinomatous element was derived from a preexisting clear‐cell adenocarcinoma through a metaplastic

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01054.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractThe purpose of this study was to evaluate whether the combined treatment of growth hormone (GH) and gonadotropins can improve ovulation stimulation in previously poor responders. Twelve patients who, had suboptimal responses in previousin vitrofertilization cycle were enrolled. They underwent 1 cycle with gonadotropin‐releasing hormone analogue (GnRH‐a) and gonadotropins and another cycle with GnRH‐a, gonadotropins, and GH. Serum gonadotropins, insulin‐like growth factor‐1 (IGF‐1), and sex steroids, including estradiol (E2), progesterone (P4), testosterone, and androstenedione were measured on Day 2 and during ovulation induction. The serum IGF‐1 level was higher in the GH cycle. There were no significant differences in the levels of the serum luteinizing hormone, E2, P4, testosterone, and androstenedione between the 2 cycles, so was IGF‐1, E2and P4in follicular fluid. Co‐treatment with GH did not improve the ovarian response. However, the GH cycles had better performance in terms of the number of oocytes fertilized and t

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01055.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractA 16‐year‐old Japanese girl was admitted for evaluation of complaints of primary amenorrhea, cyclic lower abdominal pain, and urinary incontinence. Her vaginal introitus appeared rudimentary with a depth of 0.5 cm and hypoplasia of the hymenal ring. A hypoplastic urethra (diameter:1cm; length: 0.5 cm) and 1 of 2 right ectopic ureters opened into the introitus. Transabdominal ultrasonography demonstrated fluid distending the uterus, the proximal 1/3 of the vagina, and the pouch of Douglas. Computed tomography (CT) and magnetic resonance imaging (MRI) confirmed the presence of hematometrocolpos and fluid collection in the pouch of Douglas. These associated anomalies can be due to faulty growth of the urogenital sinus. In addition to the transabdominal ultrasonography and CT, MRI was useful in the diagnosis and evaluation of vaginal agene

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01056.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractObjective: To assess the use of transvaginal ultrasound and colour Doppler imaging in the detection of ectopic pregnancy.Materials and Methods: Seventy‐one patients with suspected ectopic pregnancies had transvaginal sonography and colour Doppler imaging performed and 61 ectopic pregnancies were confirmed at surgery. Various ultrasound features on transvaginal B mode scanning were noted and the resistance index of peritrophoblastic flow in the adnexal masses computed.Results: The use of transvaginal B mode imaging alone in the diagnosis of ectopic pregnancy achieved a sensitivity of 98% and a positive predictive value of 86%. The mean gestational age at time of diagnosis was 6 weeks 5 days (range 4 weeks to 13 weeks 2 days). The use of transvaginal colour flow imaging did not increase detection rates of ectopic pregnancy. The mean RI values for patients with or without ectopic pregnancy were almost identical.Conclusion: Colour Doppler imaging failed to improve on the results of transvaginal B mode sonography in the detection of ectopic pregnanc

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01057.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractAlmost all cases with malignant transformation of a mature cystic teratoma of the ovary have been reported to be associated with squamous cell carcinoma. We describe a very rare case of mucinous cystadenocarcinoma with sarcoma‐like mural nodules arising in an ovarian teratom

ISSN:1341-8076    

DOI:10.1111/j.1447-0756.1996.tb01058.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY