摘要:

A previous experimental study by the present authors revealed that microcirculatory disturbances are produced by locally‐applied female sex hormones in the cheek‐pouch of hamsters. On the basis of this, the present study was designed to elucidate possible aberration in microvascular permeability induced by these female sex hormones. The permeability characteristics of the vascular wall were evaluated after intraveneous injections of a protein‐bound dye ‐ Evan's blue ‐ whose leakage into the perivascular tissue was considered to indicate increased permeability. In addition, endothelial damage was assessed by vascular labelling with a carbon‐ink suspension. Estrogens and progesterone, in contrast to chorionic gonadotropin, were found to provoke endothelial damage and increased vascular permeability. These findings agree with the clinical features of pregnancy

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01897.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

The effect of locally applied female sex hormones ‐ Gonadex®, Ovex‐B®, Stilbol®, and Progesteron® ‐ on the second phase of inflammation, vascular proliferation, has been explored by micro‐angiography of the micro‐vascular architecture of the rabbit's ear. The estrogens and progesterone stimulated vascular proliferation at the site of a primary micro‐trauma (the injection). Chorionic gonadotropin, however, did not induce any recognizable micro‐vascular proliferation. These findings are discussed in the light of present knowledge of hormonal influence on the

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01898.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

The effect of decalcification on the inductive activity of cementum and dentin was tested by implanting decalcified human roots into the subcutaneous tissues of the rat.No new cementum was seen. The first six months showed marked deep resorption and the second a re‐calcification of the remaining dentin. Decalcification with 5 per cent neutral EDTA destroyed the cementogenetic inductive influence of cementum and dentin previously noted in undecalcified implants.The theoretical implications of the findings were discusse

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01899.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01900.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

During a 5 day period without oral hygiene, 4 groups each consisting of 3 subjects with healthy gingivae, rinsed their mouths with solutions of tetracycline, vancomycin, polymyxin B or distilled water. Gingival plaque accumulated rapidly in the group rinsing with water, while tetracycline, and to a lesser degree vancomycin and polymyxin B inhibited plaque formation. Clinical gingivitis was not observed in any of the participants, but gingival exudate and leukocyte emigration were noted and seen to increase during the experimental period, especially in the water group. Rinsing with antibiotics inhibited these signs of subclinical inflammation to varying degrees. The bacterial composition of the gingival plaque changed in the water group during the experimental period towards a higher percentage of gram‐negative bacteria, following the pattern observed in previous investigations. Tetracycline markedly reduced the numbers of gingival plaque organisms, while polymyxin B favored a proliferation of gram‐positive cocci and short rods and depressed gram‐negative bacteria. Rinsing with vancomycin resulted in a pronounced shift towards an almost pure gram‐negative plaque flora. It is concluded that local administration of antibiotics with a limited spectrum may be useful for the study of the pathogenicity of the different components of the gingival microbia

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01901.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

The cultivation in vitro of adult human gingival tissue without cellular de‐differentiation, is possible for periods of up to four days. During this time predictable results are best achieved in the first forty eigth hours. Thereafter epithelial encirclement endangers the vitality of the explant. Studies of gingival tissue physiology in vitro are therefore best carried out during this time interva

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01902.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

During successive growth stages in the human embryo, the basal cells of the developing epidermis and specific areas of the oral mucous membranes are observed to be one of two types. One type is represented by a cuboidal cell which contains a large, round nucleus which occupies the majority of space in the cell. The cytoplasm of this cell is granular and slightly eosinophilic. This basal cell is located in the oral epithelium of the lips, cheeks, and soft palate. The other cell type is represented by a tall columnar cell which is polarized by the presence of an oval nucleus in the pole of the cell furthest away from the cell border in contact with the mesenchyme. The polarization produces a clear zone in the cell which is due to the fact that most of the cytoplasm appears to be missing. Small amounts of cytoplasm are present in the cell in the form of fine granules and filaments. It is possible that the granules are filaments seen in cross section. It was impossible to determine this conclusively with the resolution of the light microscope. The polarized, columnar, basal cells were observed in the epithelium of the gum ridge, hard palate, and epidermis.The speculation was offered that the morphologic difference in the basal cells in areas destined to become masticatory and lining mucosa in the adult, may be a reflection of a genetic bias of these tissues to develop along predetermined pathways to become a cornified or a non‐cornified stratified squamous epithelium. The differentiation may initially take place at the same time oral mucosa is differentiated to become dental lamin

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01903.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

摘要:

The distribution of the different esterases was investigated in human gingiva. The α naphthyl acetate method showed increased activity of non‐specific esterase in the region of the granular layer in orthokeratotic gingiva. A similar enzyme distribution was noted with the naphthol AS‐LC method, which suggests that the two methods are demonstrating the same enzyme. The latter method was, however, not as satisfactory as the former due to crystal formationndoxyl acetate esterase activity was also increased in the region of the granular layer. This increased activity seems to indicate that the esteraset are related to cytoplasmic autol

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01904.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY

ISSN:0022-3484    

DOI:10.1111/j.1600-0765.1967.tb01905.x

出版商:Blackwell Publishing Ltd    

年代:1967

数据来源: WILEY