摘要:

AbstractTo improve the welding strength, an in vitro study was performed to investigate the bonding strength of CO2laser nerve welding (LNW), with and without the use of human albumin solution, dried albumin solution, egg white, fibrinogen solution, fibrin glue, and red blood cells as a solder. Fifteen different combinations of laser power (50, 100, and 150 mW) and pulse duration (0.1 to 3 s) were used with a spot size of 320 μm. The results have been compared to suture, fibrin glue, and laser‐assisted nerve repair (LANR). The strongest welds (associated with whitening and caramelization of tissue) were produced at 100 mW with pulses of 1.0 s and at 50 mW with pulses of 3 s. The use of a dried albumin solution as a solder at 100 mW with pulses of 1 s increased the bonding strength 9‐fold as compared to LNW (bonding strength 21.0 ± 8.6 g and 2.4 ± 0.9 g, respectively). However, positioning the nerves between cottons soaked in saline for 20 minutes resulted in a decrease of the bonding strength (9.8 ± 4.5 g). The use of a 20% albumin solution and egg white, both at 50 mW with pulses of 3 s, resulted in a bonding strength of, respectively, 5.7 ± 2.1 g and 7.7 ± 2.4 g. Other solders did not increase the bonding strength in comparison to LNW. The substantial increase in bonding strength for some solders suggests that it is worthwhile to investigate the dehiscence rate and nerve regeneration of solder enhanced LNW in an in vivo study. © 1994 Wiley

ISSN:0738-1085    

DOI:10.1002/micr.1920150112

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractPerivascular sympathectomy, which has been used for vasospastic disorders of the hands, was examined in experimental models. Perivascular sympathectomy was performed on the central ear vessels and forepaw metacarpal vessels of the rabbit and on the common digital vessels in the monkey. The effects on adrenergic nerves were studied using a glyoxylic acid‐induced fluorescence method. Adrenergic nerves were removed only at the site of the perivascular sympathectomy and the distal adrenergic innervation appeared normal. Because the distal sympathetic nerves appeared normal after the operation, it should rather be called adventitectomy and we feel its clinical effects should be reevaluated. © 1994 Wiley‐Liss,

ISSN:0738-1085    

DOI:10.1002/micr.1920150113

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractIt has long been known that the antigenicity of tissues is depressed when they are kept at a very low temperature. In this study, Lewis rats and Brown Norway (B.N.) rats were used because these species are significantly dissimilar at the major histocompatibility complex (MHC) Femoral arteries were harvested from Lewis rats, frozen while lowering the temperature in a stepwise fashion to −70°C. After three weeks of cryogenic storage, the arteries were transplanted into Lewis and B.N. rats. At various times from the first to the twelfth week after surgery, grafted vessels were observed, and pathological and electron microscopic studies were carried out. The vessels were found to be in good condition at the end of the 12 week observation period. These results strongly suggest that prolonged cryopreservation of vessels makes allotransplantation without immunosuppression possible. © 1994 Wiley‐Liss

ISSN:0738-1085    

DOI:10.1002/micr.1920150114

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractOn the dorsum of adult Sprague‐Dawley rats, 3 × 7 cm pedicle flaps were raised and a temporary arteriovenous shunt (AVS) from anastomosis of the tail artery and vein was placed beneath. Fourteen, 21 and 28 days later, the pedicle flaps were converted to island flaps leaving only the AVS attachment. The degree of subsequent flap viability was directly related to the amount of time before flap conversion. At 14, 21 and 28 day intervals, there was 33.4%, 73.5% and 98% flap viability, respectively. Long‐term AVS patency was found not to be required for flap survival. Normal hair growth, quantity and quality, occurred in only the 28 day delay group. Microangiography and histologic examination revealed extensive neovascularization from both the AVS artery and vein extending into the muscle, subcutaneous tissue and skin layers of each island flap.In summary, neovascularization of a large random pattern musculocutaneous island flap is possible using a temporary arteriovenous shunt. Flap survival is directly related to the length of time between AVS placement and cutaneous pedicle division, although long‐term AVS patency is not required for continued flap viability. Hair growth may directly reflect the degree of underlying neovascular maturation. This AVS neovascularization technique could be applied to create new donor sites for free tissue transfer. © 1994 Wiley‐

ISSN:0738-1085    

DOI:10.1002/micr.1920150115

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractA reproducible technique has been developed to create reversible middle cerebral artery (MCA) stenosis in the cat. Under pentobarbital anesthesia, the right eye was enucleated, MCA dissected and a suture looped around the vessel. A short segment of thicker suture was set horizontally on the MCA. The looped suture was then tied and the segment suture removed, resulting in partial stenosis. The knot could be easily removed, restoring blood flow.Perfusion and diffusion‐sensitive magnetic resonance (MR) images were obtained over the next 6 hours to document cerebral blood flow abnormalities and developing ischemic changes, respectively. Laser‐Doppler was performed to further document reduced flow through the ipsilateral hemisphere following MCA stenosis. Histopathologic sections were assessed for ischemic damage.Our results show this to be a reliable model of MCA stenosis and reperfusion, which is suitable for the evaluation of acute cerebral perfusion abnormalities resulting from arterial stenosis. © 1994 Wiley‐Lis

ISSN:0738-1085    

DOI:10.1002/micr.1920150116

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractFive latissimus dorsi musculocutaneous flaps (LD flap) were used for reconstruction with prostheses after resection of tumors between 1984 and 1991 in our hospital. Bony structures were reconstructed with prostheses and in three cases autoclaved autobone grafts were also needed. The prostheses and adjacent grafts were then wrapped by the LD flaps. Tumor sites included one humerus, two thighs, and two knees. All but one case healed primarily. The sole case of infection was successfully treated with debridement and irrigation. Due to the LD flaps' plentiful blood supply, we believe infection of the prosthetics can be avoided and good clinical results can be achieved using the flap with autoclaved autograft prosthetic composite reconstruction. © 1994 Wiley‐Liss, I

ISSN:0738-1085    

DOI:10.1002/micr.1920150117

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

摘要:

AbstractMicrosurgical replantation has been attempted in the distal phalanx of the digits. Twenty‐three complete, single digit amputations are reviewed. The patients' ages ranged from 9 months to 48 years. Viability was 78%. Sensory recovery averaged 7 mm static two‐point discrimination. Range of motion in the distal interphalangeal joint of the finger and the interphalangeal joint of the thumb averaged 64 and 51 degrees, respectively. Eight of the 17 successfully replanted digits had mild to moderate atrophy. Eighty‐two percent of patients were able to use the replanted digit successfully in their daily work. We feel that distal digital replantation is rewarding. In successful cases, it always preserves acceptable function and good appearance at a price of an average of 2.3 months off work. © 1994 Wiley‐L

ISSN:0738-1085    

DOI:10.1002/micr.1920150118

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

ISSN:0738-1085    

DOI:10.1002/micr.1920150119

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

ISSN:0738-1085    

DOI:10.1002/micr.1920150120

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY

ISSN:0738-1085    

DOI:10.1002/micr.1920150101

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1994

数据来源: WILEY