ISSN:0738-1085    

DOI:10.1002/micr.1920100402

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractThis study examined the microcirculatory alterations in the hindlimb of the rat caused by ischemia and vascular washout with lactated Ringer's solution. Experimental groups consisted of innervated and denervated animals, each subjected to 2 hours of hindlimb ischemia. The ischemic period was then followed by either vascular washout or no washout prior to reperfusion. The cutaneous capillary blood flow was measured using laser Doppler velocimetry. The results demonstrated a substantial increase in early reperfusion flow above baseline in the innervated groups, more apparent in the group subjected to vascular washout. In all cases where there was elevated early flow, later flow levels were decreased. The results and proposed mechanisms of the response are discussed.

ISSN:0738-1085    

DOI:10.1002/micr.1920100403

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractIn the rat, the serratus anterior and latissimus dorsi muscles receive axial vascular pedicles from the thoracodorsal artery. This anatomy was confirmed by dissections, and 10 microvascular transfers of the latissimus‐serratus flap on a common pedicle were performed with a 90% success rate. The flaps had an average weight of 1.8 g. This flap is a reliable small animal model for microvascular muscle transplants and contains sufficient tissue to be used in multiple biochemical assay

ISSN:0738-1085    

DOI:10.1002/micr.1920100404

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractVein grafts are used extensively to repair blood vessels. However, when suitable vein segments are unavailable, alternative graft materials must be used. This study tested the suitability of 1 mm diameter polytetrafluoroethylene (PTFE) grafts for small‐calibre arterial replacements. Grafts of 4 mm length were inserted microsurgically into the iliac arteries of 26 rats. The grafts were removed between 3 and 22 months postoperatively and examined with light microscopy and scanning and transmission electron microscopy (SEM:TEM). Anastomotic intimal hyperplasia was minimal, consisting of a few smooth muscle cells extending 100–200 μm onto the graft. The rest of the PTFE was covered with endothelium. In a few isolated areas, there was a subendothelial layer of smooth muscle, 2–10 cells thick. The short segments used in this study were highly successful, with an overall long‐term patency rate of 80%. These grafts showed no evidence of excessive neo‐intimal h

ISSN:0738-1085    

DOI:10.1002/micr.1920100405

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractThe need to more fully understand the function and physiology of the free jejunal graft prompted us to develop a new canine model. Twelve dogs were used to transplant a free jejunal graft in the neck with proximal and distal stomas exteriorized to the skin. The techniques used, complications encountered, and the potential for acute and chronic studies with this animal model are presented.

ISSN:0738-1085    

DOI:10.1002/micr.1920100406

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractWe report a series of 164 patients who underwent phrenic neurotization to elements of the brachial plexus with root avulsion injuries. Recipient nerves included musculocutaneous nerve in 125 patients (78 direct neurotizations and 48 with intervening autograft), median nerve in 10 patients, and a variety of other nerves in 28 patients. Sixty‐five patients presented a follow‐up period of 2 or more years. Of this group, 55 patients (84.6%) achieved a recovery of M‐3 or better. We observed no long‐term deleterious effects on respiratory f

ISSN:0738-1085    

DOI:10.1002/micr.1920100407

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractThis study recognizes recent advances in the understanding of the anatomy and physiology of peripheral nerves at the cellular level. It has reproduced study conditions originally advocated by de Medinaceli and coworkers, with modifications. Eighty‐four rats were divided into three groups. Group A underwent sciatic nerve transection and standard perineurial repair. Group B nerves were frozen, severed with a vibrating blade, and reconnected by tubulization with a rubber cuff while bathed in solutions designed to inhibit Ca++‐calmodulin activation, maintain colloid osmotic pressure, and mimic ambient electrolytic conditions. Group C underwent a similar procedure as group B, with the rubber cuff replaced by a polyglycolic acid mesh. All animals were randomized and evaluated functionally in terms of a sciatic index. By post‐operative day 225, animals of group A recovered 37% of function, group B recovered 74%, and group C recovered 67%. Compound action potential recordings revealed a velocity recovery of 41% in group A, 70% in group B, and 81% in group C. Microscopic evaluation provided evidence for corresponding structural improvement. This new method of nerve repair is uncomplicated, relatively inexpensive, and easily adaptable to other animal m

ISSN:0738-1085    

DOI:10.1002/micr.1920100408

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractA young adult male presented with a traumatic amputation at the upper third of his left leg and an extensive soft tissue loss around his left knee. A free musculofasciocutaneous flap was elevated on the anterolateral part of the amputated segment and transferred to the soft tissue defect around the proximal left tibia in order to avoid an above‐knee amputation. The entire flap depends on the anterior tibial artery for its blood supply. The anatomy of the flap is outlined. The importance of the musculocutaneous blood supply as well as the presence of an extensive fascial component make the flap very reliable. An 18‐month follow‐up period showed a uniformly well‐contoured soft tissue coverage and an optimal functional

ISSN:0738-1085    

DOI:10.1002/micr.1920100409

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractVascular bypass has been a successful procedure for the salvage of ischemic limbs. Amputation after vascular bypass procedures alone is common when extensive ulceration, osteomyelitis, or bone‐tendon exposure is present, especially in the diabetic patient. We report two patients in whom the foot was salvaged by microsurgical free flap after revascularization with bypass grafting. Both patients are diabetic who presented with severe arteriolosclerotic foot, associated with extensive ulceration as well as bone and tendon exposur

ISSN:0738-1085    

DOI:10.1002/micr.1920100410

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY

摘要:

AbstractA new, simple, and atraumatic technique for prevention of tension at the site of an anastomosis during end‐to‐end vascular anastomoses without using an approximator clamp is descri

ISSN:0738-1085    

DOI:10.1002/micr.1920100411

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1989

数据来源: WILEY