摘要:

We describe the second reported patient with nodular fasciitis involving the dermis. Our case was morphologically a typical example of nodular fasciitis, but was distinctive by its cutaneous location and recurrence. As in the first reported case, the unexpected dermal involvement caused diagnostic difficulty, despite a typical histology.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01252.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

A case of basal cell carcinoma with “monster cells” is reported. Clinically, the lesion presented as a red nodule on the forearm of a 58‐year‐old male. The histologic picture was striking, with large, “monstrous” nuclei scattered throughout a well defined nodule. Basal cell carcinoma with monster cells appears to represent a histologic variant of nodular basal cell carcinoma. The prognostic significance of the monster cells remains to be

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01253.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

A 46‐year‐old women developed polyarthritis, purpurie skin rashes, nasal septal perforation and marginal furrowing of corneas in 1980. Monoclonal IgG, kappa cryoglobulinemia was found in the patient's serum. No underlying lymphoproliferative disorder has been found in ten years since her original diagnosis. In 1991, she developed palpable purpura on both lower extremeties with subsequent necrosis and ulceration. A skin biopsy revealed fibrin thrombi within capillaries in the papillary dermis, and immunoflourescence studies showed IgG and light chain kappa within the fibrin thrombi. An electron microscopy study showed intravascular immunoglobulin crystalloid structures with a mean diameter of 80.3A° (8.03 nm), mixed with fibrin and red blood cells. The exclusive vascular location of these crystalloids may have implication in the pathogenesis of skin les

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01254.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

The apocrine nevus (AN) is a rare tumor occurring in the upper chest and the axilla. We report a case of a AN in a 33‐year‐old female occurring unilaterally. The presenting complaint related to tenderness and swelling in the right axilla. The initial impression was hidradenitis suppurativa. The gross specimen revealed the presence of irregular thickening just beneath the dermal subcutaneous interface. Microscopically the lesion was composed of mature apocrine glands with apical snouts. The glands were arranged in lobules divided by thin fibrous septa. immunohistochemical studies revealed the following profile in the glandular epithelium: positive low molecular weight cytokeratin, epithelial membrane antigen, and gross cystic disease fluid protein reactivity and negative high molecular cytokeratin and S‐100 protein reactivity. Carcinoembryonic antigen reactivity was found in the duet epithelium. Ultrastructural studies revealed cells lining the lumen of the glands with a concentration of granules in the apical region and light and dark granules. These findings support the previously described light microscopic observations and provide unreported ultrastructural studies in this rare

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01255.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

The etiology of verruciform xanthoma, a rare lesion that usually occurs in the oral mucosa, is unknown. A viral etiology has been speculated since extraoral lesions usually occur in the genitalia. We present, to the best of our knowledge, the first reported case of verruciform xanthoma in an immunocompromised patient with chronic graft versus host disease. Immunohistochemical studies showed a few ham 56 (a macrophage marker) positive foam cells, both in the dermis and within the epidermis, supporting a role for an epidermal process in production of the foam cells. Staining for human papillomavirus protein (HPV) showed reactivity of some of the nuclei in the dermal Histiocytes, butin situhybridization for HPV types 6/11, 16/18, and 31, 33 was negative. These results support an eopidermal process as the stimulus for the foam cell formation but fail to demonstrate HPV as the cause.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01256.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

A case of cesarean scar endometriosis with massive decidualization is presented. The 25‐year‐old patient had an extensive, ulcerated lesion that mimicked malignancy microscopically due to myxoid change with alveolar patterns reminiscent of some soft tissue sarcomas, signet ring‐like cells similar to mucin‐producing carcinoma, and pseudoinfiltration of the fascia. The myxoid tissue was positive for acid mucopolysaccarides but negative with PAS. Decidual cells were vimentin positive and keratin negative. No atypia or mitoses were seen. The pseudoinfiltrative aspect was due to abundant extracellular matrix that separated the fascicles of the fascial tissue. There was a metaplastic decidual “proximity effect” in the surrounding, unaffected dermis, which may be responsible for the expansile features of the lesion. This case exemplifies the differential diagnosis of myxoid endometriosis with malignant conditions

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01257.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01258.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01260.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01261.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1993.tb01263.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY