摘要:

Topical treatment of a number of out‐patients with psoriasis vulgaris resulted in reduced induration and diminished thickness of the layer of scales but complete involution was not obtained. A sequential photographic study of the macroscopic appearance of the lesions over a 3‐month period of treatment revealed that artificially produced excoriations and a horny layer without scales were prominent features. The view is put forward that the cutaneous reaction to the injury probably elicited by the excoriations, together with an unsatisfactory treatment, may give rise to tissue changes which counteract the effect of topical treatm

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00159.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Actinic reticuloid was observed in a patient following the development of porphyria cutanea tarda. A cutaneous lymphoma‐like infiltrate was found histologically and at the ultra‐structural level. In the infiltrate, the main population was histiocytic, with some mast cells and mononuclear cells. Most of the histiocytic cells contained numerous typical Langerhans granules and worm‐like structures. Crystalloid cytoplasmic inclusions were occasionally det

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00160.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

An ultrastructural examination was carried out on the skin of six children suffering from Mucopolysaccharidosis I (MPSI or Hurler's disease) and MPS II (Hunter's disease). Both intracellular mucopolysaccharides and lipids were observed. The dermal cells, i.e. fibroblasts, macrophages, were loaded with multiple vacuolar inclusions thought to be of lysosomal origin. They appeared either content‐free or filled with granular, fuzzy and/or pseudomyelinic structures. Identical abnormalities were observed within the Sebwann cells, smooth muscle cells and keratinocytes. Mast cells showed peculiar “worm‐like” inclusions apart from their normal granulations.Since ultrastructure of a skin sample may provide as much data as brain, liver or kidney, cutancous electron microscopy can be recommended to confirm a diagnosi

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00161.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Cellular patterns of healing subcutaneous connective tissue were studied histologically in 22 pediatric surgical patients using the CELLSTIC device. This wound drain, specially developed for this purpose, consists of a standardized, viscose cellulose sponge inside a thin silicone rubber tube. When left between the wound edges. wound exudate flows through the drain, allowing its cells to attach themselves to the sponge surface. The sponge serves as a framework within which the cells may migrate, divide and transform. During the first 12 h the cellular pattern in the sponge resembles that of peripheral blood, whereafter the number of polymorphonuclear leukocytes, almost exclusively neutrophils, gradually increases. Later on, monocytes, macrophages and lymphocytes invade. Fibro‐blasts were usually seen at the end of the third day postoperatively, but in some cases the first fibroblasts appeared even earlier. CELLSTIC neither disturbs normal wound healing nor increases the rate of wound infections. CELLSTIC, as a cell culturein situ, provides a practical way to study human connective tissue regeneration under both physiological and pathological condition

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00162.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

The activities of five enzymes were determined by fluorometric micromethods in epidermal tumors (basal and squamous cell epithelioma, verruca sebrrhoica and keratoacanthoma) and compared to the activities in the adjoining, apparently normal epidermis. Most activities were higher in the tumoral tissues.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00163.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A case of eruptive porokeratosis of Mibelli with diverse morphologic features, including circinate maculir, circinate plaque and verrucous varieties is presented. No matter how variable the clinical presentation may be, the histologic hallmark of porokeratosis, the cornoid lamellae, is always present. The cornoid lamellae vary in height in relation to how prominent the thready ridge of the clinical lesion appears. Our patient also had psoriasis which initially masked the porokeratotic lesions both elinically and histologically. Awareness of the various clinical expressions of porokeratosis of Mibelli would 1) make unnecessary the segregation of certain forms of porokeratosis into separate entities, and 2) help in the recognition of less classical forms of porokeratosis.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00164.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00165.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00166.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00167.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00168.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY