ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00579.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00580.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00581.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Neurofollicular hamartoma is an unusual, previously undescribed neoplasm characterized by a proliferation of spindle cells and hyperplastic pilosebaceous units. Five cases were reviewed. The lesions presented as single, asymptomatic, smooth, flesh‐colored papules. Four were on the nose, and one on the adjacent nasolabial fold. Immunoperoxidase studies performed on two cases utilizing antibodies to S‐100 antigen were positive in both. These lesions share some histological and clinical features with angiofibroma and neurofibr

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00582.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Dermatologic literature has debated the occurrence of concommitant morphea‐scleroderma (M‐S) and lichen sclerosus et atrophicus (LSA) for sometime. Presentation of a case which has the appearance of both M‐S and LSA creates a diagnostic dilemma frequently unresolved even by histopathology. Routine hematoxylin and eosin stained sections may add to the confusion and the difficulty of the differentiation, but examination for the presence or absence of elastic fibers in the upper corium of the lesions affords a definitive separation of these two condi

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00583.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Three lesions showing squamous cell carcinoma in situ (Bowen's disease) within seborrheic keratosis are reported: 2 were located symmetrically on the legs of one of the patients, with a lesion recurring after surgery. Nests of atypical cells were seen in the transitional zone between the 2 components of the third lesion.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00584.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

A cutaneous ciliated structure from the lower neck of a 61‐year‐old man having seromucous, sebaceous and respiratory‐type differentiation is reported. The finding of continuity between endodermal and ectodermal structures in the reported lesion suggests an origin from the branchial apparatus. Many lesions with similar appearance have been labeled bronchogenic though these, in fact, may have branchial origins. The term cutaneous bronchogenic cyst, implying an origin from the tracheobronchial tree, maybe misleading and should be reconsidered for those lesions with respiratory‐type differentiation in the low

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00585.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

A 41‐year‐old woman with localized lipodystrophy histologically showed lymphohistiocytic inflammation within adipose tissue at the periphery and loss of adipose tissue in the center of the lesion. Ultrastructurally, various degrees of lipophagocytosis by macrophages and giant cells were seen, starting with the projection of cytoplasmic processes into the fat droplet and engulfing pieces of the fat droplet which finally were digested. Laboratory investigations revealed a high serum γ‐globulin level and a positive antinuclear antibody, suggestive of a connective tissue disease or autoimmue d

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00586.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Oral melanoacanthoma is a rarely‐reported, benign pigmented lesion of oral mucosa. Spongiosis was only recently mentioned as a light‐microscopical finding occasionally seen in oral melanoacanthoma, and the formation of spongiotic intraepithelial vesicles to our knowledge has never been reported. The authors discuss a case of a 34‐year‐old, black woman who acutely developed extensive hyperpigmented oral lesions which on the biopsy showed both intraepithelial dendritic melanocytes and severe spongiosis forming intraepithelial vesicles. These lesions resolved spontaneously in a few months which led the authors to believe that the term melanoacanthoma, implying that it is a tumor, is a misnomer. This report supports findings of other investigators who consider oral melanoacanthoma to be a mucositis with unusual proliferation of dendritic melanocytes in the ep

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00587.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

We present a 73‐year‐old man with a 5‐year history of dermatitis herpetiformis who developed lesions with the clinical, histologic, and immunologic features of bullous pemphigoid. Direct immunoflurescence testing of a skin biopsy demonstrated both granular deposition of IgA, predominantly in the papillary bodies, and linear deposition of IgG and C3 at the basement membrane zone. This mixed direct immunofluorescence pattern, typical for dermatitis herpetiformis in the type of IgA deposits, but also typical for pemphigoid in the linear localization of IgG and C3, is unusual. This case emphasizes that even after a specific diagnosis has been established, if the clinical morphology or response to therapy changes, repeat histologic and immunofluorescence studies may be indicated in diagnosis and management of patients with bullous di

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1989.tb00588.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY