摘要:

A clinico‐pathologic study of lymphomas of the skin included 14 cases of mycosis fungoides, 14 of primary lymphoma and 22 of secondary lymphoma. Mycosis fungoides has clinical and histopathologic features which allow for separation from the other groups. In this study, patients with mycosis fungoides had a longer duration of history and presented with papules, plaques, erythroderma or generalized dermatitis but not with tumor nodules ab initio. A confident histologic diagnosis required the presence of the mycosis cell, which was usually present in association with a mixed inflammatory cell infiltrate. Another important histologic feature was the presence of invasion of the epidermis by the mycosis cells singly and/or in nests (Pautrier microabscesses). Primary and secondary lymphomas of the skin presented clinically as multiple tumor nodules and histologically as a monomorphic infiltrate of neoplastic cells confined to the dermis and subcutis. A feature which has not been adequately documented in a large series was the presence of an associated prominent epithelioid cell reaction in several cases from all three group

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00897.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Light and electron microscopic observations were carried out in three cases of granuloma faciale. The dense granulomatous infiltrate of the corium showed: 1) more eosinophils than suspected by light microscopy, most of them with degenerative changes; 2) Charcot‐Leyden chrystals; 3) numerous large histiocytes with their cytoplasms filled with lysosomal vesicles containing various inclusions (lamellar figures, myelin bodies, circular concentric organelles, digested membrane structures). The lack of Langerhans granules in dermal cells seems a valid reason to differentiate granuloma faciale from eosinophilic granuloma of the skin, usually considered a variety of histiocytosis X. No evidence of bacterial or viral infections was noticed. Granuloma faciale, despite its uncertain etiology, seems to represent a true entit

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00898.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

A case of sebaceous carcinoma with pagetoid involvement of the palpebral and bulbar conjunctival epithelium was studied by light and electron microscopy. Ultrastructurally, the neoplastic cells within the conjunctival epithelium were identical to those in the underlying invasive sebaceous carcinoma. Evidence of gradual transformation of conjunctival epithelial cells to the neoplastic sebaceous cells or transitional forms between conjunctival epithelial cells and sebaceous cells was not encountered. The evidence thus supports the theory that the neoplastic cells in the conjunctival epithelium are the result of secondary invasion by the underlying sebaceous carcinoma.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00899.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Four cases of pseudoxanthoma elasticum (PxE) are reported and the light and electron microscopic appearances described.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00900.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Microscopically monitored excision for the treatment of skin cancer is becoming increasingly popular among dermatologists. One decision faced by beginning histographic surgeons involves the choice of apparatus for making the frozen sections. This paper compares the freezing microtome with the cryostat and gives details of the University of Iowa method, which employs the Slee© cryostat

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00901.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

This paper describes a solitary lesion of the hand thought to represent a variant of eccrine nevus composed solely of acrosyringeal elements.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00902.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00903.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00904.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY