摘要:

Human orf is usually considered a rare disease caused by a virus belonging to the para‐vaeeinia subgroup of pox viruses and transmitted to man from sheep and goats. This paper presents 119 new human cases with epidemiological, clinical, histopathological and ultrastructural findings. Erythema multiforme was found to be a common complication of human orf. Other complications tended to be caused by overtreatment. Electron microscopy of negatively stained suspensions from lesions was found to be the best and most rapid diagnostic method availabl

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00179.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

A 27‐year‐old patient developed superficial basal cell epitheliomas approximately 20 years after taking Fowler's solution. One of the lesions was successfully treated with topical 2% 5‐fluorouracil solution under occlusion. Sequential biopsies of the lesion before, during and after therapy were examined by light and electron microscopy, and the changes at various stages are described. Changes occurred only in tumor cells and adjacent epidermis, and only after occlusion of 5‐FU. After one week of occlusive therapy, focal discontinuities in the basal lamina and intercellular spaces were wider with reduction and condensation of tonofilaments. Mitochondrial degeneration was seen along with irregularities in nucleoli. These changes were most prominent after two weeks of occlusive therapy, and many degenerating keratinocytes were seen detached from other cells. One month after cessation of therapy, the entire area was excised, and no evidence of tumor w

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00180.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Two immunohistochemical methods, using the enzyme horseradish peroxidase, the direct immunoperoxidase (DIP) and the immunoglobulin‐enzyme bridge (IEB) method were applied on 129 skin specimens of 81 patients with lupus crythematosus, bullous pemphigoid, pemphigus vulgaris and rosacea. These methods were compared with each other and with the immunofluorescence (IF) method. The DIP method was preferred to the IEB method because of the greater contrast between the specific staining and the nonspecific staining of the former. The results obtained with both peroxidase methods were comparable with those of the IF metho

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00181.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

An osteogenic sarcoma arising in an old burn scar on the right thigh of a 70‐year‐old woman is described. Salient features of this rare cutaneous tumor were: a large pinkish exophytic mass, spindle and oval cells, multiple foci of osteoid formation, atypical osteoblasts and multinucleated giant ce

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00182.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

We are reporting seven cases with nevus lipomatosus cutaneus superficialis. A review of the literature indicates that this is a relatively rare type of connective tissue nevus with little more than 50 cases recorded. Localization of the cutaneous nodular lesions over the upper thigh and buttock and histologic findings of fat lobules within the substance of the nevoid malformation differentiate these lesions from other varieties of the connective tissue nevi.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00183.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Three patients who developed a psoriasiform skin eruption following oral practolol administration are described with particular attention to the cutaneous histological changes. Although the clinical picture resembled psoriasis, the histological one did not, resembling rather that seen in a drug eruption. The possibility of an early lymphoma could not be excluded on purely histological grounds.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00184.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Silver sulfadiazine, at a concentration of 10 μg/ml, has been demonstrated to possess bothin vitroandin vivoantiviral activity against herpesvirus hominis

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00185.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1975.tb00186.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY