摘要:

When halcinonide cream was used for prolonged periods in patients affected by alopecia areata or alopecia totalis, marked and steady regrowth of hair was observed.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00889.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Ten patients with traumatic alopecia (trichotillomania) were being investigated histologically and. in five of them, hairs from the affected scalp area were plucked out for direct microscopic examination. Some histologic features appear to be specific markers for traumatic alopecia: empty hair ducts, plucked out hair bulbs, clefts in hair matrix, catagen involution of empty outer root sheaths, Miescher's trichomalacia in the deep dermis and torn‐off sebaceous glands. Other signs are unspecific, such as presence of catagen and anagen VI hairs, infundibular plugging, melanin in keratin plugs and in the dermal papilla. The relative frequency of the different histopathologic features was evaluated. When little clinical information is available, a diagnosis of traumatic alopecia can he supported by skin biopsy. The histologic picture of trichotillomania is always incomplete, depending upon factors such as intensity of pulling or/and time of biopsy after pluckin

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00890.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

This is a light‐ and electron‐microscopic study of excoriated, recalcitrant psoriatic lesions in ambulatory patients undergoing topical treatment. During regeneration of a stratum corneum without scales, in areas showing excoriations bounded by a non‐cornified epidermis, horny cell layers, designated I and II, are formed. In areas in which excoriations are delimited by an epidermis with a retained stratum corneum, the latter is composed of a horny cell layer I and/or II or III. The horny cell layers differ, as shown by light‐and electron‐microscopy. In the less fresh excoriations, a homogeneous substance, which includes fibrin deposits, is observed. This substance is also seen frequently in the stratum corneum. In the less fresh excoriations and in the stratum corneum there are numerous polymorphonuclear leukocytes. In these locations, however, they are only found simultaneously with the homogeneous substance containing fibrin deposits. Polymorphonuclear leukocytes are also seen in the dermal papillae and in the non‐cornified epidermis, particularly in the macroscopically “old” excoriations. The changes observed in these recalcitrant lesions have been interpreted as secondary and are believed to be expressions of a non‐specific reaction to the mechanical damage to which the ambulatory patients have constantly exposed the lesions. They are not interpreted as changes in the psoriati

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00891.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Electron microscopic observations in three cases of granular cell myoblastoma revealed that this tumor is made up of two types of cells. 1) Granular cells grouped into nests, surrounded by a basement membrane, and displaying characteristic inclusions. Numerous processes were observed close to these cells, showing filamentous and microtubular components lying parallel to their axes. 2) Satellite fibroblasts which included angulated bodies. The relationship between these two types of cells is discussed.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00892.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Trichoadenoma of Nikolowski is a rare benign tumor of the skin with hair follicle‐like direction of differentiation. This tumor is less mature than trichofolliculoma and more differentized than tri‐choepithelioma. Probably because of its rarity it has not been a well recognized tumor. We are reporting on eight cases of trichoadenoma to further define this benign gro

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00893.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

In recent years the phenomenon of transepithelial elimination has been found to be the underlying mechanism in a variety of skin disorders. “Perforating dermatoses” may show transepidermal or transfollicular elimination or a combination of the two. A case of papular granuloma annulare is reported, where in one lesion the pilary apparatus actively participated in the elimination of necrobiotic collagen from the dermis. To our knowledge, perforating granuloma annulare with a transfollicular pathway has not previously been described. Also, a classification of perforating dermatoses is presen

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00894.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00895.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1977.tb00896.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY