ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00404.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

We report pigmented lesions in 2 white male patients, which were clinically diagnosed as superficial spreading malignant melanoma and histologically showed combined features of superficial spreading malignant melanoma in situ and pigmented basal cell carcinoma. The significance of this association is not known but is most likely very rare.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00405.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Six patients with macular amyloidosis were investigated by electron microscopy and various morphological changes in fibroblasts were identified. Many cells, which seemed to be macrophages by light microscopy, proved to be fibroblasts. The digesting action of fibroblasts was well developed and many melanosomes were taken into the cells making the cells resemble melanophages. The fibroblasts extended long, thin and branched cytoplasmic processes to surround the amyloid mass, and the cells selectively extended these into the narrow spaces between collagen and amyloid. The fibroblast showed highly developed endocytotic activity and probable ingcstion of amyloid by pinocytosis or phagocytosis. The developed rough cndoplasmic reticulum contained much protein and was active in secretion.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00406.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Tissue from the cutaneous metastases of bronchial carcinoid was examined. Fine argyrophil secretory granules were demonstrated in the cytoplasm of the abnormal cells which showed positive labelling with neuron‐specific enolase. Ultrastructural studies revealed numerous electron‐dense membrane bound neuro‐secretory granules, 50–300 nm in diameter. Other characteristic features included inter‐digitating pseudo pod‐like processes (up to 2 μ in size) in the cytoplasmic membrane, perinuclear filaments, a well‐defined Golgi zone and numerous larg

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00407.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Chrysiasis is a rare, permanent, pigmentation of the skin caused by the parenteral administration of gold preparations followed by subsequent exposure to ultraviolet light. We report a case of chrysiasis following gold therapy for rheumatoid arthritis, wherein ultrastructural analysis combined with x‐ray energy spectroscopy afforded precise identification and localization of the gold pigment in skin biopsy specimen

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00408.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

A case is described of malignant B‐cell lymphoma with scleroderma‐like manifestation. Using different monoclonals as B‐cell markers the tumor appeared to he positive for surface immunoglobulins (Smlg) and for B2‐antigen, but negative for intraeytoplasmic immunoglobulin (Clg), BA2‐ and FMC7‐antigens. Therefore, the tumor could be determined as a highly differentiated Sm‐positive early B‐cell type of B‐cell lymphoma. In this clinically rare manifestation of cutaneous B‐cell lymphoma aspects of the cell morphology and of cellular mediated immunity ar

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00409.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Flame figures are a characteristic histologic feature of Wells'syndrome (eosinophilic cellulitis). In this light and electron microscopic study, the ultrastructure of flame figures is described. Collagen fibers were encrusted with free eosinophil granules. No collagen damage was found. Flame figures most probably represent a transient result of unusual eosinophil activity.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00410.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

A 51‐year‐old mason presented with a large tumour on his scalp which had developed over the previous 2 years. Histological examination showed the presence of large vessels with muscular coats some of which appeared to be venules and others arterioles. They had markedly swollen cuboidal endothelial cells and a surrounding mononuclear cell infiltrate which in areas formed lymphoid follicles some of which had germinal centers. There was no evidence of tissue or blood eosinophilia. The unusual clinical and histological features of this case are emphasized and the nosology of this rare condition is discus

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00411.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

Characlcristic moniliform hairs of monilcthrix were ultrastructurally examined. By scanning electron microscope, nodes and internodes were seen alternating on the affected hair; the nodes were normal in apparance and thickness, while the internodes were thin and showed ridges and flutes. By transmission electron microscope, the cross sections of the internodes revealed wrinkling of the hair coticular cells and a reduced number of the cortical cells. Cross sections of the cortical cellsper seshowed a similar size and a normal keratin pattern in both nodes and internodes, compared with those of control hairs from normal individuals. From these findings, the internodes seemed to be the pathological portions of the monilifonn hair, and such abnormal thinning of hair shaft might tie caused by a periodical dysfunction of the hair matrix, especially in the hair cortex.

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00412.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY

摘要:

We retrospectively analyzed our laboratory reports of tissue‐specific autoantibodies (TSA) in 38 patients withalopecia areata(AA) and 31 patients with vitiligo. These reports were based on standard indirect immunofluorescence (IF) procedures, employing monkey tissues as substrates. One or more TSA were detected in 39% of serum samples. Thyroid (microsomal and/or thyroglobulin) antibodies had the highest occurrence rate and, as compared with the normal population, were detected at a greater frequency in both vitiligo and AA. Over half (58%) of our patients with vitiligo had one or more delectable TSA, while only 28% of patients with AA had such antibodies. When compared with the normal population, the occurrence rate of TSA was higher in patients with vitiligo. The only remarkable finding in AA was a higher than normal occurrence rate of antithyroid antibodie

ISSN:0303-6987    

DOI:10.1111/j.1600-0560.1984.tb00413.x

出版商:Blackwell Publishing Ltd    

年代:1984

数据来源: WILEY