摘要:

Infectious arthritis in renal transplant patients may be a commonly diagnosed condition with traditional bacterial organisms isolated. However, since nontuberculous mycobacteria are ubiquitous in the environment, immunocompromised individuals may suffer from infections with these organisms. Concomitant gout and Mycobacterium avium intracellulare septic arthritis is described for the first time in this clinical setting. Appropriate cultures should be performed even in the setting of crystal arthritis in posttransplant patients when clinically indicated.

ISSN:1420-4096    

DOI:10.1159/000174113

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

The mechanism of renal tubular urate transport disorder was studied by the pyrazinamide and probenecid tests in a 12-year-old hypouricemic boy suffering from the normotensive form of Gordon’s syndrome, with increased distal tubular reabsorption of NaCl (confirmed by the hypotonic saline diuresis test). The aim of the study was to determine the impact of oral hydration during the tests on the phases of renal tubular urate transport: before (I), and during long-term hydrochlorothiazide therapy (0.5 mg/kg BW/day) (II). In both periods (I, II), presecretory reabsorption of urate was within normal limits. Hypouricemia in our patient was caused by decreased postsecretory reabsorption, with or without simultaneous increase of tubular urate secretion. The degree of overhydration determines which of these mechanisms is responsible for increased renal urate clearanc

ISSN:1420-4096    

DOI:10.1159/000174114

出版商:S. Karger AG    

年代:1997

数据来源: Karger

ISSN:1420-4096    

DOI:10.1159/000174115

出版商:S. Karger AG    

年代:1997

数据来源: Karger