ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Clinical laboratory evaluation of adrenergic function is lacking in sensitivity. Recent studies suggest that components of the Valsalva maneuver can be used to evaluate adrenergic function. Late phase II and phase IV are primarily regulated by peripheral and cardiac sympathetic activity, respectively. With progressive adrenergic failure there is a loss of IIian increase in lleand a loss of IV in that order. Baroreflex gain can be described by the heart period/blood pressure (BP) response. An alternative approach of expressing latency instead of gain is of interest but is of uncertain validity. Evaluation of heart rate recordings in the frequency domain using power spectral analysis can be used to study parasympathetic/sympathetic balance in humans. Its value as a clinical test remains to be established. Prolonged tilt is a sensitive and probably specific test of vasodepressor syncope. Isoprotefenol infusion during tilt is of doubtful specificity.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Most studies show a decline in autonomic nervous system (ANS) function with advancing age. The occasional heterogenous responses of ANS to aging, however, suggest that psychosocial and physiologic factors alter aging of ANS function.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

It is now well recognized that autonomic dysfunction may occur in disorders affecting the various body systems. Over the past year important observations have been reported in congestive cardiac failure, reflex sympathetic dystrophy (RSD), acquired immune deficiency syndrome (AIDS) and diabetes mellitus.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

The autonomic nervous system is affected by most conditions that cause peripheral neuropathy. Autonomic dysfunction may be clinically significant in some conditions such as diabetes, amyloidosis, Cuillain-Barré syndrome and porphyria, but in many the autonomic disturbances are of only minor clinical importance. Clinical tests of both sympathetic and parasympathetic function are necessary to establish the diagnosis.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Dysautonomic symptoms are associated with many disorders of the central nervous system, in some of which the autonomic dysfunction is particularly conspicuous or the major cause of disability. New neuroimaging procedures and microneurographic techniques have helped to clarify the underlying pathophysiology and to distinguish or classify disorders that are clinically similar. Recent studies also suggest that the autonomic nervous system is involved more frequently or extensively than previously thought in certain neurological conditions such as multiple sclerosis or human immunodeficiency virus (HIV) infection, and have helped to define the nature of its involvement in other disorders.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

The group of primary autonomic failure (AF) syndromes comprises pure AF (PAF), in which there are no central neurological signs, and multiple system atrophy (MSA) in which AF is accompanied by the overlapping degenerative disorders, striatonigral degeneration and olivopontocerebellar atrophy. Patients with these syndromes deteriorate progressively but, based on an understanding of the precise sites of the lesions, there are several ways of alleviating their deterioration, in particular the most disabling symptom, postural hypotension. The principles can be used in the treatment of AF in other general medical disorders, such as diabetes.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

New developments defining the relationship between 5-hydroxytryptamine (5-HT; serotonin)1Band 5-HT1Dreceptors are reviewed and a novel pain control system involving spinal 5-HT3receptors is described. The emerging roles of 5-HT receptor mechanisms in migraine and in the craving for alcohol are discussed.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID

摘要:

Recent research on the site of action of morphine, its distribution following systemic administration and activity in a model of neuropathic pain is reviewed. Neuropeptides and pain is discussed in relation to tachykinins and their antagonists, cholecystokinin (COO and its antagonists and somatostatin.

ISSN:0951-7383    

出版商:OVID    

年代:1992

数据来源: OVID