ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00309.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00310.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00311.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00312.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

In many species, genital activity proceeds according to a seasonal rhythm. Variations concern the secretion of gonadotrophic and steroid hormones, sexual activity and spermiogram parameters. In man, a statistical evaluation of reproductive physiology rhythms is being processed. The first results display seasonal variations of hormonal secretions (testosterone, follicle stimulating hormone, luteinizing hormone), and sexual activity as determined by certain environmental factors (birthrates, sale of contraceptives, rape charges, etc.). The seasonal alterations in human semen composition are less well understood, however, there is a definite increase of necrospermia during winter. All research on the effect of drugs that interfere with spermatogenesis and potency must take any seasonal changes into account.

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00313.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Of 26 previously normospermic patients treated with MOPP (nitrogen mustard, vincristine, procarbazine and prenisone) for Hodgkin's disease, 22 had azoospermia, 2 had severe oligozoospermia below 0.1 times 106spermatozoa/ml, 2 had 5 times 106spermatozoa/ml. Follicle stimulating hormone (FSH) increased significantly in all but 2 patients, but the luteinizing hormone (LH) increase was not significant. Prolactin, testosterone and 17β‐oestradiol levels were unmodified. Chemotherapy is widely used for malignant and non‐malignant diseases, the various drugs having different levels of toxicity. In order to prevent male sterility as a result of chemotherapy, the physician must choose the therapeutic agents carefully and may recommend cryopreservation of the patient's semen prior to therapy. In addition, the minimize the hazards of chemotherapy, the testis may be cooled during drug infusion and the germinal epithelium may be put to rest by desensitization through a LH releasing hormone an

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00314.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00315.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

This brief status report is based on the round table discussion on inhibin at which progress in purification was one of the topics discussed. During the past 3–4 years more and more reports on the purification of ILA have appeared. Although in many instances recovery problems persist, the difficulties are not insurmountable. With the participation of more laboratories in the isolation work, we can expect significant new data on the identification of ILA and resolution of many outstanding issue

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00316.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1982.tb00317.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY