ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01137.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThis report describes the procedure for percutaneous injection of silicone to form plugs in the vas deferens. The injection of 0.1–0.16 ml Chinese‐made silicone into 14 men achieved occlusion of a 1‐cm length of the vas. Sperm concentrations declined within 1 month of the operation and azoospermia was achieved in all men by 9 m

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01138.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThe present study reports the outcome of operations to remove MPU plugs from 130 men who had had occlusions of the vas deferens for between 0.5 and 5 years. The female partners of all the men achieved a pregnancy over a period of 0.5–4 years after the reversal operatio

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01139.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThis report describes the safety and efficacy of the procedure for percutaneous injection of medical‐grade polyurethane elastomer (MPU) to form plugs in the vas deferens. The injection of 0.16–0.22 ml MPU in 53 men resulted in occlusion and azoospermia in 85% of the men after 12 months; 96% achieved azoospermia by 2 years. The success rate of the method and the rate of sperm suppression to azoospermia depended on the shapes of the plugs; this was determined by palpation after insertion. There were few complications and the results are discussed in terms of the reversibility potential of this met

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01140.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummarySemen analyses of 529 men who consulted our department due to infertility problems, were related to the time period prior to conception, with factors adversely affecting the fertility of the female partner taken into consideration. The statistical method used was Cox's proportional‐hazard model of regression. Untransformed, logarithmically transformed and dichotomized semen analysis variables were included in the calculations. The relationship between the following parameters and the probability of conception was examined: sperm count, sperm motility, progressive sperm motility, morphology and sperm motility remaining 24 h after ejaculation. All variables co‐varied with the probability of conception; however, the exact type of relationship could not be determined by regression analyses. Cox's model assumes an exponential relationship. Our data suggest that this assumption is not suitable for fertility investigations. Using conventionally defined limiting values for normal and pathological semen quality, statistical analysis yielded significant differences in fertility between both categories for all of the variables considered; in the stepwise regression analysis, however, it could be shown that progressive motility and morphology alone were sufficient to discriminate between normal and pathological semen quality. The results are interpreted as indicating that, as a result of semen analysis, it is possible to predict the individual probability of conception if the exact shape of the relationship can be determined, which, up to now, has not been accomplis

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01141.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThree hundred and twenty‐eight consecutive treatment cycles in 168 couples were analysed retrospectively in order to examine the influence of conventional semen analysis results on the outcome of in‐vitro fertilization and embryo transfer with respect to the occurrence of both fertilizations and pregnancies. All treatments were performed under maximally standardized and controlled conditions. Each of the three main determinants of the spermiogram, namely the concentration, motility and morphology of sperm in seminal plasma, was of significant importance for fertilization and subsequent pregnancy. Best correlations were achieved by counting the number of progressively (a + b) motile sperm and the number of normally formed sperm in seminal plasma. The pregnancy rate was reduced significantly in cases in which the sperm concentration was<10 × 106ml‐1(P<0.01), or in which there was<40% progressively motile sperm (P<0.001), or<30% normally formed sperm (P<0.001). If more than one parameter in the spermiogram was abnormal, the fertilization rate depended mainly on the most disturbed sperm parameter. The implantation rate as well as the pregnancy rate was reduced significantly in patients with low progressive sperm motility and normal morphology rates. The difference could only be attributed partially to the lower number of embryos replaced. In conclusion, subnormal sperm quality seems to interfere with developmental stages beyond the process of fertili

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01142.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThe migration‐sedimentation technique (MST) has been proposed as a means of separating high quality motile spermatozoa. The present study was conducted in order to evaluate whether sperm performance following separation by MST predicts their fertilizing capacity in an in‐vitro fertilization (IVF) programme. Ninety semen specimens were analysed for use in an IVF‐embryo transfer (ET) programme. Each specimen was divided into two parts: one was processed in the IVF programme and was used after sperm swim‐up separation for insemination of human ova. The other aliquot (0.2 ml) was separated by MST, and the sperm then characterized by their concentration, motility, degree of motility and morphology. Sperm characteristics after separation by MST were then correlated with the results of the IVF‐fertilization rates. In 79 of 90 IVF‐ET cycles, at least one oocyte was fertilized. All post‐MST sperm characteristics were significantly higher in cycles with fertilizations compared to IVF cycles without fertilization. A larger percentage of the total motile spermatozoa were recovered after MST in semen specimens with fertilization, compared to semen specimens without fertilization (39.9 ± 3.6 and 20.6 ± 6.6%, respectively; P<0.05). This value was correlated with the percentage of fertilized oocytes (r= 0.24; P25%(P<0.005), or when more than 1.5 times 106motile spermatozoa were recovered after MST (P<0.0001). As sperm characteristics after MST correlated significantly with their fertilizing capacity, the MST test could be used in evaluation of the fertilizing capacity

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01143.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Nearly one‐third of paediatric surgery consists of operations on the inguinal canal. A late complication of this is male sterility due to damage to the vas deferens. Correction of this preventable cause is problematical and there is poor outlook for the severly oligozoospermic and azoospermic male. The true incidence of unilateral damage to the vas deferens is unknown, as this can be masked by a normal reproductive tract on the contralateral side. However, occasionally more subtle changes other than direct transection and fibrosis of the vas deferens can prevent sperm transport. This may be related to damage to the vas pseudocilia, it's auto‐nomic and peptidergic innervation leading to defective contractility. This report presents four cases, which confirm the vunerability of the vas deferens during inguinal surgery and highlight azoospermia as a late complicat

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01144.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0105-6263    

DOI:10.1111/j.1365-2605.1992.tb01145.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY