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21. |
Fetal Renal Biopsy: Technique Development |
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Fetal Diagnosis and Therapy,
Volume 8,
Issue 2,
1993,
Page 135-143
Winston A. Campbell,
Harold T. Yamase,
Carolyn A. Salafia,
Anthony M. Vintzileos,
John F. Rodis,
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摘要:
Fetal/neonate kidneys obtained at the time of autopsy were utilized to determine a suitable needle biopsy gauge to obtain renal parenchyma for histologic evaluation. Twenty-one fresh kidney specimens from 11 fetuses/neonates between 16-40 weeks gestation were used to obtain needle biopsies using 20-, 18-, 16-, and 14-gauge biopsy catheters. The specimens were graded according to the presence of normal histologic features of renal parenchyma. Seventy-five renal biopsies were obtained. The biopsy histology was inteφreted using a grading system based on the presence of normal features of the renal parenchyma. Sixty-three (84%) of the samples were graded histologically as adequate (cortex or medulla present). Samples with both cortex and medullary structures present (completely adequate) were obtained in 39/63 (62%) of these adequate biopsies. The 14- and 16-gauge biopsy catheters gave the best results, respectively yielding 79 and 69% completely adequate biopsies. This is in contrast to the 20- and 18-gauge catheters that respectively yielded 35 and 25% completely adequate biopsies. Our initial results indicate that adequate kidney biopsies can be obtained. However, the current technique is associated with core sample disruption when the smaller gauge catheters are used. This could account for the low rate of completely adequate samples with the smaller gauge catheters. A different sampling technique is needed to overcome sample disruption, to determine the smallest catheter gauge that will yield a suitable tissue sample for histologic evaluation
ISSN:1015-3837
DOI:10.1159/000263762
出版商:S. Karger AG
年代:1993
数据来源: Karger
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22. |
Transvaginal Chorionic Villus Sampling Using Transabdominal Ultrasound Guidance: A New Technique for First-Trimester Prenatal Diagnosis |
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Fetal Diagnosis and Therapy,
Volume 8,
Issue 2,
1993,
Page 144-148
Lee P. Shulman,
Joe Leigh Simpson,
Sherman Elias,
Richard E. Felker,
Donald S. Emerson,
Owen.P Phillips,
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摘要:
Transvaginal chorionic villus sampling (CVS) using concurrent transabdominal ultrasound guidance was performed in 20 women who desired CVS but could not be offered transcervical or transabdominal approaches because of uterine position and placental location. Satisfactory amounts of chorionic villi were obtained in all 20 cases with no maternal discomfort, an occurrence that contrasts with our experience in transvaginal CVS using endovaginal ultrasound guidance. We believe that transvaginal CVS using concurrent transabdominal ultrasound guidance warrants consideration as an alternative technique for first-trimester CVS in selected patients.
ISSN:1015-3837
DOI:10.1159/000263763
出版商:S. Karger AG
年代:1993
数据来源: Karger
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23. |
Contents, Vol. 8, Supplement 2, 1993 |
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Fetal Diagnosis and Therapy,
Volume 8,
Issue 2,
1993,
Page -
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PDF (1870KB)
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ISSN:1015-3837
DOI:10.1159/000263897
出版商:S. Karger AG
年代:1993
数据来源: Karger
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