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11. |
Influence of Propranolol Plasma Levels on Hemodynamics during Coronary Artery Bypass Surgery |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 455-463
J.,
Sill Michael,
Nugent Thomas,
Moyer Luis,
Torres Hartzell,
Schaff John,
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摘要:
Hemodynamic effects of propranolol during coronary artery surgery were investigated in 26 patients who chronically took propranolol and who received a standardized morphine/diazepam/pancuronium/halothane anesthetic. Effects were shown by correlating logarithm of the plasma propranolol concentrationsversuspercentage change in hemodynamics following stressful events (induction, intubation, skin incision, sternotomy, and sternal retraction). Log propranolol and hemodynamics following cardiopul-monary bypass also were correlated. A broad range of propranolol levels were observed. Levels (range and mean · SD) were preinduction 0–96 (25.6 · 21.6) ng/ml; preincision 0–86 (27.2 · 24.4) ng/ml; and sternal retraction 0–92 (28.2 · 25.4) ng/ml. The range of hemodynamic responses to stressful events also was broad. Representative changes between preincision control and sternotomy were (range and mean · SD): HR −8–30 (7 · 10) beats/min; PCWP 1–21 (8.5 · 4.6) mmHg; CI −0.2–1.1 (−0.2 · 0.7) 1 · min−1· m−2, and SVR −244–1,288 (310 · 388) dyn · s · cm−5. By the time of sternal retraction, CI had declined from preincision values in 14 patients. Linear regression analysis demonstrated an inverse correlation between log propranolol and magnitude of HR, MAP, PCWP, and CI response to stressful stimulation. A direct but statistically weaker correlation with SVR also was seen. Significant correlations between log propranololversushemodynamic response to anesthetic induction andversuspostcardiopulmonary bypass hemodynamics were not observed. The authors conclude that propranolol, in proportion to the log plasma level, attenuated stress-induced changes in HR and to a lesser degree changes in MAP, PCWP, and CI and that at higher levels this effect was achieved with some decline in CI and increase in SVR.
ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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12. |
Evaluation of Peripheral Nerve Stimulators and Relationship to Possible Errors in Assessing Neuromuscular Blockade |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 464-466
K.,
Mylrea S.,
Hameroff J.,
Calkins C.,
Blitt L.,
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PDF (186KB)
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摘要:
Voltage and current output characteristics were measured on six commercially available peripheral nerve stimulator devices. The results are evaluated as possible sources of variability in peripheral nerve stimulator function and neuromuscular blockade assessment. The authors found significant differences in output voltage waveform and in maximum current into a 470 ohm load (21.4 to 128 mA.). Output current decreased from 25 to 88% in the different devices, with a load impedance increase from 470 to 10,000 ohms. Due to the variability in peripheral nerve stimulation units and the decrease in current output at higher load impedance, less than supramaximal stimulation is possible with erroneous interpretation of neuromuscular blockade.
ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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13. |
The Rovenstine Lecture, 1983Cardiovascular Anesthesia Perceptions and Perspectives |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 467-474
Arthur,
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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14. |
Efficacy of Oral Premedication for Pediatric Outpatient Surgery |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 475-477
Robert,
Brzustowicz Dunkin,
Nelson Eugene,
Betts Kathleen,
Rosenberry David,
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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15. |
Hematocrit and Blood Volume Control during Cardiopulmonary Bypass with the Use of Hemofiltration |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 478-480
Peter,
Klineberg Chin,
Kam David,
Johnson Timothy,
Cartmill John,
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PDF (259KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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16. |
Doppler Localization of the Internal Jugular Vein Facilitates Central Venous Cannulation |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 481-481
Dwight,
Legler Michael,
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PDF (162KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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17. |
Hemodynamic and Two‐dimensional Transesophageal Echocardiographic Analysis of an Anaphylactic Reaction in a Human |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 482-484
Paul,
Beaupre Michael,
Roizen Michael,
Cahalan Ricki,
Alpert Lydia,
Cassorla Nelson,
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PDF (251KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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18. |
Acute Pulmonary Edema in Healthy Teenagers Following Conservative Doses of Intravenous Naloxone |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 485-486
Donald,
Prough Raymond,
Roy John,
Bumgarner Gary,
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PDF (183KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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19. |
Pharyngeal and Esophageal Perforation Following Endotracheal Intubation |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 487-488
James,
O'Neill Joseph,
Giffin James,
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PDF (206KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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20. |
Hemodynamics and Histamine Release during Induction with Sufentanil or Fentanyl |
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Anesthesiology,
Volume 60,
Issue 5,
1984,
Page 489-490
Carl,
Rosow Daniel,
Philbin Christine,
Keegan Jonathan,
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PDF (244KB)
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ISSN:0003-3022
出版商:OVID
年代:1984
数据来源: OVID
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