ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

摘要:

The excretion of3H-gallamine was studied in the dog. Eighty-four per cent of the drug was recovered unchanged from the urine in 24 hours. Following ligation of both renal pedicles a sustained blood gallamine concentration was maintained for 24 hours, producing prolonged paresis. Unlike3H-d-tubocurarine,3H-gallamine was excreted in the bile in negligible amounts only.

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

摘要:

A technique for spinal anesthesia in which a subarachnoid tap is done with a needle whose tip is 32-gauge is described. The method was used in 500 patients. The incidence of mild postspinal headache was 0.4 per cent, with an additional 1 per cent of slight transient headache. These results support the leakage theory of the etiology of post-lumbar-puncture headache. The chief complications encountered with this technique were inadvertent dural puncture with 18- or 20-gauge introducer needle (with its own associated incidence of headache) and, rarely, an inability to aspirate or inject fluid through the #32 needle. The technique was useful clinically although it required more time and care than using #22 or #26 spinal needles or single-dose epidural technique.

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

摘要:

The effect of a mixture of droperidol and fentanyl citrate in a ratio of 50:1 (Innovar) on the vestibular systems of young, healthy men was examined. Droperidol (5 mg) with fentanyl (0.1 mg) suppressed the vestibular reaction of the inner ear to caloric stimulation but not the vestibular reaction to galvanic stimulation, suggesting that the site of action was within the labyrinthine part of the vestibular system. The mean time from completion of drug administration to maximal labyrinthine suppression was nine minutes and the mean duration of suppression 198 minutes.

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

摘要:

Eighty to 100 per cent oxygen, breathed by lambs one or two weeks of age, is lethal after two to four days. Artificial ventilation did not aggravate or significantly ameliorate the pulmonary response. Lambs ventilated with air on respirators for comparable periods had no significant pulmonary damage. The cause of death of the oxygen-treated lambs was the pulmonary injury, characterized by edema. Studies of the excised lungs showed that the lesion was spotty, that the normal-appearing portions of the lung were normally distensible, and no significant alterations in pulmonary surfactant occurred. Several methods of assessment of the mechanical derangements are presented.

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

摘要:

Effects of spinal and epidural anesthesia uncomplicated by premedication or surgery were studied in 20 normal subjects. Venous blood flow, vascular resistance and venous distensibility of forearm and calf vessels were measured simultaneously before and after induction of spinal or epidural anesthesia. In anesthetized calf vessels, blood flow and vascular distensibility increased and vascular resistance decreased. Changes in cardiac output, whether decreased, increased or unchanged, did not affect the ratio of calf blood flow to cardiac output, which in all instances increased following spinal and epidural anesthesia. Changes in arterial blood pressure did not correlate with changes in cardiac output alone or changes in total peripheral resistance alone. However, changes in arterial blood pressure correlated with the interaction of changes in cardiac output and changes in total peripheral resistance.Evidence presented indicates that arterial hypotension induced by either spinal or epidural anesthesia may be due primarily to increased vascular distensibility of capacitance vessels and secondarily to decreased resistivity in pre- and postcapillary resistance vessels in the anesthetized area.

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1969

数据来源: OVID