ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

摘要:

Thirty-six mongrel dogs were ventilated with oxygenated fluorocarbon liquid (FX-80) for an hour and then reconverted to breathing gaseous oxygen. For several days after breathing this liquid, the dogs were hypoxemic while they breathed air. The authors attributed this to residual fluorocarbon in the lung and/or partial airway closure. By ten days after liquid ventilation, Pao2's had returned to pre-experimental control levels. Pathologic examination of the lungs three hours after termination of liquid ventilation disclosed an acute exudative inflammatory reaction largely confined to the bronchioles. By 72 hours the acute reaction had subsided and the dominant change consisted of vacuolated intra-alveolar macrophages, presumably containing fluorocarbon. At ten days, macrophages were still present, but generally in much smaller numbers; after a month only scattered small groups were found. At 18 months the lungs were normal.

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

摘要:

The sensitivities and response times of six ventilators in the assist mode were measured. The withdrawal volumes necessary to cause triggering were: Bennett MA-1, 0.5 ml; Bennett PR-2, 1.5 ml; Bird Mark 8, 1.5 ml; Bourns LS 104–150, 0.1 ml; Dräger Spiromat 661, 1.0 ml; Ohio 560, 0.5 ml. The times necessary for the ventilators to respond to these withdrawals were: Bennett MA-1, 82 msec; Bennett PR-2, 226 msec; Bird Mark 8, 157 msec; Bourns, 36 msec; Dräger, 434 msec; Ohio, 123 msec. The maximal rate at which a ventilator can assist is inversely proportional to the response time.

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

摘要:

Following intravenous injection of lidocaine, 10 mg/kg, into cats anesthetized with pentobarbital: 1) the mean threshold stimulus for direct cortical inhibition increased 30—50 per cent; 2) GABA-induced inhibition was not blocked; 3) the discharge rate of L-glutamate-activated neurons decreased. After local application of lidocaine from multibarrel micropipettes: 1) neither inhibition evoked by surface stimulation nor that induced by GABA was reduced; 2) the spike amplitude and rate of L-glutamate-evoked discharges were eventually depressed. It is concluded that the elevated thresholds for direct inhibition of cortical neurons that follow intravenous injection of lidocaine are more likely to result from conduction block along inhibitory fibers than from specific blockade of inhibitory synapses on the cortical neurons.

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1971

数据来源: OVID