ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

摘要:

Ventilation-compression frequencies and ratios during cardiopulmonary resuscitation in dogs with ventricular fibrillation and ventilation frequencies in apneic healthy human subjects were studied. Lung inflations interposed between sternal compressions gave better ventilation and about equal carotid blood flows as compared to simultaneous inflations. A ventilation—compression ratio of 3/15 (using air) maintained normal oxygenation and ventilation, whereas 6/30 did not In apneic adults with two inflations (tidal volume 1,000 ml) every 15 seconds, oxygenation and ventilation were adequate with FiO26O compressions per minute, while 120 compressions per minute gave insignificantly greater flows than 72 compressions per minute. The recommendation of a ventilation—compression ratio of 2/15 for one operator and 1/5 interposed for two operators (compressions at one second intervals without interruption) is sound.

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

摘要:

Arterial blood samples were studied for hematocrit, oxygen saturation, PaO2acid base balance, glucose, pyruvate, lactate, excess lactate, citrate, α-ketoglutarate, malate, acetyl coenzyme A and adenosine triphosphate in adult patients anesthetized with ether or halothane-nitrous-oxideoxygen. All types of operations except cardiovascular, neurological and obstetrical were included. No deviations from standard anesthetic or fluid replacement methods were employed except the substitution of saline for dextrose solutions. There was no evidence of shock in any case.Significant variation between anesthetic agents occurred in only 3 parameters. End of operation samples showed levels of total lactate, pyruvate and excess lactate consistently higher with ether than with halothane-nitrous-oxide-oxygen. Total acid increase was also greater with ether. Blood levels of acetyl coenzyme A and the three acids of the tricarboxylic acid cycle were not influenced by type of anesthetic agent or the presence or absence of excess lactate. Lactate levels over 3 mEq./liter were associated with decreased blood levels of adenosine triphosphate, an effect more marked with ether than halothane. One possible explanation for higher lactate levels with ether is based on the sympathomimetic action of the agent A second, hypothetical explanation, suggests a depressant effect of ether on the intramitochondrial electron transport chain or the shuttle systems for transfer of reducing equivalents across the milochondrial membrane.

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

摘要:

Eighteen subjects were successively given spinal anesthesia with 50 to 75 mg. lidocaine, and epidural anesthesia with 15 to 35 ml of 2 per cent lidocaine containing 1:200,000 epinephrine. Mean levels of cutaneous analgesia (pin prick) and molor block (electromyography) were T 2.3 ±1.8 and T 5.1 ± 2.4, respectively, with spinal anesthesia, and T 3.6 ±1.2 and T 8.2 ±2.6 with epidural anesthesia. Mean inspiratory capacity fell 8 per cent with spinal anesthesia and 3 per cent with epidural anesthesia. Mean expiratory reserve volume fell 48 per cent with spinal anesthesia and 21 per cent with epidural anesthesia.

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID

ISSN:0003-3022    

出版商:OVID    

年代:1967

数据来源: OVID