ISSN:0148-6403    

DOI:10.1002/hed.2890010502

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThe frequency with which carcinoma develops in laryngeal keratoses is a controversial subject. A study of 92 cases of laryngeal keratosis with a minimum of five years' follow‐up resulted in identification of three patients (3.26%) who developed laryngeal carcinoma. A review of the literature reveals that, in series of keratoses defined by stringent pathologic criteria, subsequent laryngeal carcinoma develops in 3.33%–4.31%. These findings support a low but predictable frequency of conversion to malignancy in laryngeal keratosis. A grading system for keratosis is presented and discussed with reference to clinicopathologic correlat

ISSN:0148-6403    

DOI:10.1002/hed.2890010503

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThis is the concluding portion of a two‐part series dealing with the effects and manifestations in the oral cavity of radiation therapy of head and neck tumors. Preradiation and postradiation extractions in dentulous patients, as well as dental maintenance of such patients (including fluoride treatments, follow‐up, and restorative care), are discussed. Guidelines for the dental management of edentulous patients are also presented at length (this section covers risk of bone necrosis, soft liners, timing of denture placement, dentures and preexisting bone necrosis, soft‐tissue necrosis and dentures, morbidity, and prosthodontic procedures). The article concludes with a brief discussion of osteoradionecrosis and soft‐tissue n

ISSN:0148-6403    

DOI:10.1002/hed.2890010504

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractIn the treatment of upper‐aerodigestive‐tract malignancy, interstitial‐implant radiotherapy differs in several physical and biologic respects from conventional external‐beam therapy: unlike external‐beam therapy, it can deliver a high central dose with a rapid fall‐off, which overcomes the central hypoxic resistance effect and yet greatly improves normal tissue tolerance. Externalbeam and interstitial‐implant therapy can also be combined to the patient's benefit; in many cases, this combination offers advantages over externalbeam therapy alone, preoperative external‐beam therapy, or aggressive surgery. The recent upsurge of interest in this modality has come about because of three developments: more suitable radioactive sources, afterloading, and computerized dosimetry. The early results in upper‐aerodigestive‐tract malignancy, both as primary and as salvage therapy, are promising; but the precise role of this treatment in our therapeutic armamentarium remain

ISSN:0148-6403    

DOI:10.1002/hed.2890010505

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractOne hundred fifty‐one patients with a history of childhood irradiation to the head, neck, and thorax had neck explorations (142 for “cold” thyroid nodules and 9 for hypercalcemia). Fifty‐nine of the patients had thyroid carcinoma, and associated glandular tumors were found in 20 others. In addition, 6 female patients developed breast carcinoma; 4 of these women also had thyroid carcinoma. In this series, 48.6% of the patients irradiated for acne and 36.4% with tonsil and adenoid irradiation developed thyroid carcinoma, but only 10.5% with thymic irradiation did so. It is suggested that the workup on these patients include not only complete thyroid and parathyroid testing, but also a careful examination of all salivary glands, both major and minor. Women should have thorough breast examinations and should perhaps be followed as if they were in the potentially high‐risk breast group. When thyroid surgery is performed, a total thyroidectomy is re

ISSN:0148-6403    

DOI:10.1002/hed.2890010506

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

ISSN:0148-6403    

DOI:10.1002/hed.2890010507

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractConcentration on tip positioning may draw a surgeon's attention away from modifying positions of the nasofrontal angle and of the columellar‐labial junction. All three landmarks are, however, vital to the establishment of desirable profiles. This article emphasizes that changes in the positioning of the columellar‐labial junction may (1) eliminate certain hazards involved in changing tip position, (2) make it possible to produce aesthetic effects that cannot be achieved with tip positioning alone, and (3) make rhinoplasty safer and more predictable in certain difficult cases. Also presented are techniques that have been found to work most satisfactorily in changing angle and position. A few patients selected from among several thousand rhinoplastic cases are analyzed to underscore the significance of this area in rhinoplastic planning. Follow‐up varied from several months to several

ISSN:0148-6403    

DOI:10.1002/hed.2890010508

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractA computed tomographic analysis of normal laryngeal anatomy was undertaken using cadaver larynxes. This was part of a larger project in which patients with laryngeal carcinoma were routinely evaluated in the computed tomographic (CT) body scanner. The appearance of normal laryngeal anatomy had to be delineated before disease processes of the larynx were evaluated, and this was accomplished using a computed tomographic technique with 5‐mm slice thicknesses and a 3‐mm overlap. The scan slices were then compared with anatomic sections taken at the same levels. The comparisons demonstrate an ideal level of accuracy that can be approached in the in‐vivo larynx only with use of the latest‐generation scanners. However, CT scanning is of immediate usefulness in the diagnosis of laryngeal pa

ISSN:0148-6403    

DOI:10.1002/hed.2890010509

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractFundamental precepts of radiation biology are presented to provide a basis for the comprehension of radiotherapy. These precepts include cell viability, randomness of cell killing by irradiation, the influence of molecular oxygen on radiosensitivity, phases of the cell cycle, and repopulation. The combined‐treatment concept is developed, and preoperative and postoperative irradiation options, as well as the optimal extent of the surgical procedure, are discussed. These principles of combined treatment are first applied to the management of neck disease, which is a common denominator to all sites. The anatomic sites of the mouth and throat are then discussed. The capabilities of radiotherapy have greatly altered treatment planning for carcinomas of the mouth and throat; one must now develop an initial overall plan that varies with the extent and anatomic site of the primary lesion, the extent of neck disease, and the probability of spread to clinically uninvolved lymphatic area

ISSN:0148-6403    

DOI:10.1002/hed.2890010510

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

ISSN:0148-6403    

DOI:10.1002/hed.2890010511

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY