ISSN:0148-6403    

DOI:10.1002/hed.2890020102

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractCancer of the nose and paranasal sinuses (SNC) has been attributed to occupational exposure to nickel, chromium, radium dichlordiethyl sulphide, isopropyl oil, and hydrocarbons. Occupational groups with an increased SNC risk include furniture, boot and shoe workers, and workers in U.S. counties heavily involved in both petroleum and chemical manufacturing; specific agents have not been identified with certainty. In most of the studies, the risk for developing SNC in the exposed workers was 21 to 100+ times greater than the risk for SNC in those who were not exposed. Undifferentiated and squamous histologies are associated with nickel refining; adenocarcinomas are found in woodworkers, boot and shoe manufacturers, and textile workers. Most occupations at risk for SNC were also at risk for cancer of other sites, particulary lung and skin cancer. Study of the epidemiology of SNC may identify unrecognized carcinogens and occupational groups at increased cancer risk.

ISSN:0148-6403    

DOI:10.1002/hed.2890020103

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractAccurate localization and diagnosis of orbital lesions is necessary to select the appropriate treatment. A systematic method of evaluating a patient with orbital disease is presented. The most common orbital lesions among children and adults are listed, and abnormalities that mimic exophthalmos are described. The tests that are most useful in evaluating orbital disease are described in detail. Several case reports illustrate the value of ultrasonography and three‐dimensional computed tomography in the localization and diagnosis of space‐occupying lesions of the orbit. Special tissue‐processing techniques can be performed on some tumors to aid in establishing a diagnosis and in planning trea

ISSN:0148-6403    

DOI:10.1002/hed.2890020104

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractSurgical excisions of vascular tumors of the head and neck are frequently associated with difficulties because of the potential of operative blood loss. The technique of selective percutaneous embolization before surgery has emerged as a valuable adjunct—and even alternative—to surgery in the management of such lesions. By reducing the blood flow to a vascular tumor or arteriovenous malformation, embolization techniques can greatly facilitate surgical excision. The participation of a qualified invasive radiologist is essential. If cases are carefully selected and procedural details strictly adhered to, this technique can be quite valuable to surgeons treating vascular lesions of the head and n

ISSN:0148-6403    

DOI:10.1002/hed.2890020105

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThree patients with infratemporal fossa carcinomas presented with severe, unrelenting facial pain, weight loss, and 5th cranial nerve deficit. Erosion of the base of the skull at the foramen ovale was present in two of these patients. Histologic diagnosis of infratemporal fossa malignancy was obtained by needle biopsy of the foramen ovale region; the technique is described. This approach to the infratemporal fossa is preferred to the more complicated external surgical approach with its greater risk of morbidity. Surgical approaches to the infratemporal fossa are also reviewed. Two of the patients were treated with radiotherapy; the third refused further therapy. Supravoltage radiotherapy with curative intent is the recommended treatment because of the difficulty of an en bloc tumor resection in the infratemporal fossa. Radioactive gold seeds may be implanted through an external surgical approach to boost the local dose.

ISSN:0148-6403    

DOI:10.1002/hed.2890020106

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractPatients with squamous cancer of the head and neck have unique perturbations of the immune system. These patients have marked depression of cellular immunity even in the early stages of disease. The known facts about the immunobiology and the immunodeficiencies that commonly occur are discussed. Also reviewed are the relationships of the immunologic deficits to stage of disease, to prognosis, and to the suspected etiologic factors of smoking, alcoholism, and malnutrition. Highlights are given of current immunotherapeutic trials. To date, most of the successful efforts in both immunobiologic research and immunotherapy of head and neck cancer have dealt with general, rather than specific, immune reactions. Future development in the area of specific immune responses may permit more meaningful measurements of tumor‐specific reactions, thus yielding useful tools for immunodiagnosis as well as providing more effective and precise methods of immunotherap

ISSN:0148-6403    

DOI:10.1002/hed.2890020107

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

ISSN:0148-6403    

DOI:10.1002/hed.2890020108

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThe embryology of the branchial (pharyngeal) region is reviewed in terms of the embryonic pharynx, branchial apparatus and derivatives, tongue, larynx, and trachea. Derivatives of the branchial pouches, grooves (clefts), and arches are analyzed in relation to each other and to the first arch syndrome. Other common head and neck defects attributable to abnormal development of the branchial region are also discussed, particularly those defects involving the incomplete degeneration or the abnormal migration of branchial tissues.

ISSN:0148-6403    

DOI:10.1002/hed.2890020109

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThe biphase external skeletal‐fixation splint (Morris splint) for mandibular stabilization has been used in cases of ablative surgery. It is a practical approach to stabilization for patients whether or not they undergo reconstruction, either immediate or delayed. The Morris splint can be applied without increasing the time required for major resection. It can be left in place for prolonged periods, but it still allows easy surgical access and easy postoperative care and observation. While not a new tool, it has been little used by the head and neck cancer surgeon, probably because it has not been presented for this purpose but rather for treating fractures. A practical approach to the use of the Morris biphase splint is presented, as well as the indications for its use and some results of our experience with this too

ISSN:0148-6403    

DOI:10.1002/hed.2890020110

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractZenker's diverticulum is a common developmental anomaly seen usually in the elderly. Carcinoma in this pharyngoesophageal outpouching has been reported in only 23 instances. A 55‐year‐old woman is presented whose only symptoms were dysphagia and periodic regurgitation of bloodstained material. Barium swallow and esophagoscopy confirmed the presence of a neoplasm, and biopsy revealed an epidermoid carcinoma. Wide field resection was followed by a full course of irradiation and secondary pharyngoesophageal reconstruction. The patient was free of disease at three‐year foll

ISSN:0148-6403    

DOI:10.1002/hed.2890020111

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY