ISSN:0148-6403    

DOI:10.1002/hed.2890100501

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractA recent preliminary report of a study to determine the patterns of invasion of squamous cell carcinoma to the nonirradiated edentulous mandible indicated that tumor entered mainly through the residual alveolar occlusal ridge.1This study has now been extended and includes both nonirradiated and irradiated mandibles. Of a total of 46 nonirradiated mandibles (10 partially dentate and 36 edentulous) invaded by tumor, 41 were invaded through the occlusal surface. This confirms the findings of the preliminary report. These findings indicate that there is a rational basis on pathologic grounds for adopting a conservative approach to the nonirradiated mandible. In 16 irradiated mandibles, the routes of tumor entry were found to be much more variable than in the nonirradiated mandible, and multiple foci of tumor invasion of the bone were often present wherever tumor in adjacent soft tissues approached the bone. This variability of tumor entry means that a conservative approach to mandibular excision cannot be pursued in the previously irradiated mandible and full‐thickness segmental resection is necessary if bone involvement appears likel

ISSN:0148-6403    

DOI:10.1002/hed.2890100502

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractFor patients with squamous cell carcinoma of the head and neck whose primary lesion is managed with radiotherapy, radiotherapy alone or in combination with neck dissection may be used to treat clinically positive neck nodes. Although these two treatment options produce similar control rates for small mobile nodes, it is our impression that radiotherapy plus neck dissection is the preferred treatment for more advanced neck disease. The question that arises is whether the addition of a neck dissection after radiotherapy will decrease the likelihood of successful surgical management of a subsequent recurrence at the primary site. In an effort to answer this question, the records of 227 patients with squamous cell carcinoma of the head and neck were reviewed. All patients had clinically positive neck nodes and were treated with radiotherapy alone to the primary lesion. There was no apparent difference in the rate of disease control at the primary site or in the ability to manage patients successfully who developed a local recurrence when comparing patients initially treated with radiotherapy alone to those managed by radiotherapy and neck dissection. We conclude that postradiotherapy neck dissection does not decrease the likelihood of successfully managing a recurrence at the primary site.

ISSN:0148-6403    

DOI:10.1002/hed.2890100503

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractThere is biologic and histogenetic plausibility for an association between salivary gland cancer and nonmelanoma skin cancer. To add further credence to this association, a descriptive epidemiologic study of salivary gland cancer incidence data from the Surveillance Epidemiology and End Results (SEER) program from 1973 to 1981 was undertaken. The objective was to determine whether the incidence of this cancer exhibited the inverse association with geographic latitude that is characteristic of skin cancer incidence. The SEER areas were grouped into three regions (north, central, and south), based on indices of ultraviolet radiation. The southern area had significantly higher rates for white males and females compared with the northern area for all histologic subtypes combined (standardized incidence ratios were 1.6 for males and 1.4 for females), as well as for specific histologic subtypes (adenocarcinoma, squamous cell carcinoma, and males only with mucoepidermoid carcinoma). However, there were no significant differences in incidence between the central and northern areas. These data provide further evidence of an association between skin and salivary neoplasms, both exhibiting a pattern of incidence suggestive of susceptibility to ultraviolet radiation exposure.

ISSN:0148-6403    

DOI:10.1002/hed.2890100504

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractThe authors report 27 cases of macrocheilia, discussing each cause individually. They classify macrocheilia according to its etiology, emphasizing the importance of an accurate diagnosis in treating the disease. The operative technique indicated for each cause is discussed. The technique basically consists of a fusiform resection, which may include a larger or smaller amount of lip tissue depending on the disease process. The incision may be interrupted at the mid‐lip and W‐plasty or lateral Z‐plasties may be used to avoid the formation of dog

ISSN:0148-6403    

DOI:10.1002/hed.2890100505

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractThe object of this study was to determine if pulmonary function tests were necessary in the preoperative evaluation of potential candidates for conservation laryngeal procedures. In addition, pulmonary complications from a series of partial laryngectomies were examined and correlated with a previous history of chronic obstructive lung disease. Ninety‐four patients with laryngeal tumors amenable to a partial procedure were assessed preoperative by testing their pulmonary function by stair‐climbing; they were considered to possess enough pulmonary function to permit a partial procedure. Pulmonary function tests were obtained in 69 of these patients. Measurements of vital capacity and forced expiratory volume in 1 ‐second were reviewed and correlated with the postoperative development of pulmonary complications to determine if these tests of pulmonary function could reliably predict which patients would be more prone to developing pulmonary complications. The results indicated that pulmonary function tests or a prior history of chronic obstructive pulmonary disease (COPD) could not reliably predict postoperative complica

ISSN:0148-6403    

DOI:10.1002/hed.2890100506

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractFour cases of primary non‐Hodgkin's lymphoma (NHL) of the thyroid were studied using flow cytometric (FCM) DNA analysis of propidium iodide‐stained nuclei retrieved from formalin‐fixed, paraffin‐embedded tissue. Two of the four cases were aneuploid and two were euploid. In the two euploid cases, both patients are alive and without evidence of recurrent disease after an average of 4 years follow‐up. Of the two aneuploid cases, one patient is alive and free of recurrent disease after 1 year. In the other aneuploid case, the patient died of disseminated disease 8 months after presentation despite having a low‐grade (follicular, predominantly small cleaved cell type) and low‐stage (tumor confined to thyroid at presentation) lymphoma. These data suggest that the DNA ploidy of primary NHL of the thyroid can be determined using fixed, paraffin‐embedded tissue. Our results also suggest that a large study to assess the prognostic value of this techniq

ISSN:0148-6403    

DOI:10.1002/hed.2890100507

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractThe ameloblastic fibroma, ameloblastic fibrodentinoma, and ameloblastic fibro‐odontoma are mixed odontogenic tumors that are considered to arise from both epithelial and mesenchymal elements of the tooth germ. This article presents the clinical and histopathologic characteristics of 23 new cases. The patients' ages ranged from 3 to 19 years (median 9). Most tumors were asymptomatic and were associated with an unerupted tooth or teeth. All patients were treated with simple enucleation of the tumor. We found that histologically these lesions comprise a spectrum. Some were probably benign odontogenic tumors (neoplasms) and others were odontomas undergoing maturation (hamartomas); however, in any given case we were, on histologic grounds, unable to differentiate the two. The majority, if not all, of our cases were nonaggressive with little or no tendency to recur, whereas some reported cases have exhibited local aggressiveness and recurrence, suggestive of neoplasia. In our opinion, it is clinically important to distinguish the mixed odontogenic tumors from ameloblastoma since the mixed tumors, found mostly in children, are relatively benign when compared to ameloblastoma, which is found in all age groups (usually adults). The usually innocuous behavior of these lesions does not justify aggressive treatment initially, and simple enucleation should be appropriate in most case

ISSN:0148-6403    

DOI:10.1002/hed.2890100508

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractAn unusual complication of radical neck dissection is presented. Necrosis of the anterior half of the tongue developed gradually within the first week of bilateral neck dissection. The patient had previously received radiotherapy.

ISSN:0148-6403    

DOI:10.1002/hed.2890100509

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY

摘要:

AbstractNeoplasia in thyroglossal duct cysts or ectopic thyroid tissue deposits is rare but well recognized. The first known case of Hurthle cell adenoma in thyroglossal duct anomaly is described. The pathologic course and treatment of Hurthle cell tumors in general is reviewed. Treatment was based on the view that neoplasms in thyroglossal duct remnants represent changes in the ectopic thyroid tissue.

ISSN:0148-6403    

DOI:10.1002/hed.2890100510

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1988

数据来源: WILEY