ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00994.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Chlorhexidine diacetate and povidone‐iodine were evaluated for fibroblast toxicity on a primary line of canine embryonic fibroblasts, and for bactericidal efficacy againstStaphylococcus aureus.The cultured fibroblasts orS. aureuswere exposed for 30 minutes to incremental dilutions of 0.5 to 0.0005% chlorhexidine diacetate, 5.0 to 0.05% povidone‐iodine, or physiologic buffered saline as a control. To determine survival, fibroblasts were trypsinized and counted;S. aureuscolonies were counted on brain‐heart infusion agar. Survival for both groups was expressed by calculating the number of living cells in test dilutions as a percentage of the number in control cultures. Fibroblast survival occurred at chlorhexidine concentrations less than 0.013% and at povidone‐iodine concentrations less than 0.5% (p<0.05). SignificantS. aureussurvival (p<0.05) was noted at chlorhexidine concentrations less than 0.05% and povidone‐iodine concentrations less than 1.0%. These data showed that all bactericidal concentrations of chlorhexidine diacetate and povidone‐iodine were lethal to canine embryonic fibroblastsin vitro, whereas non‐lethal concentrations allowed significant bacte

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00995.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Partial rostral hemimandibulectomy was performed in 10 adult dogs. The temporomandibular joints (TMJs) were examined radiographically and tomographically before surgery, and mandibular stability was evaluated before and immediately after surgery. Radiographic, tomographic, and hemimandibular mobility assessments were made again at months 3 and 6. The TMJs were examined grossly and histologically in five dogs euthanatized at month 3 and in five dogs euthanatized at month 6. Statistically significant hemimandibular instability (p<0.05) persisted in all subjects throughout the study. The radiographic appearance of the joints remained unaltered; however, space asymmetry was identified in postoperative tomograms of three dogs at month 3 and four dogs at month 6. The TMJs were grossly normal at necropsy. Histologically, there were degenerative changes in articular cartilage and subchondral bone in all of the joints. The authors conclude that partial rostral hemimandibulectomy causes TMJ degeneration, as a consequence of hemimandibular instability or abnormal loading, or both.

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00996.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00997.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

An autogenous free vascular bone transfer using a segment of ulna along with its periosteum and vascular pedicle was developed. The vascular pedicle, based on the common interosseous artery and vein, emerged where muscular branches from the cranial interosseous artery enter the extensor carpi ulnaris and lateral digital extensor muscles. Four autogenous heterotopic (ulna to tibia) vascular transfers by microvascular anastomosis and two avascular transfers were performed to compare the osteogenic potential and viability of free revascularized grafts with avascular bone grafts. Successful microvascular anastomosis was demonstrated in three of the four vascular transfers by early bone scanning using technetium‐labeled polyphosphate. Radiographically, there was more periosteal new bone and callus formation in the successfully revascularized bone transfers than in the failed vascular transfer and the avascular controls. Histologically, viable bone with an intact medullary and periosteal vascular supply was recognized in the grafts successfully revascularized by microvascular anastomosi

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00998.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

An anatomic study was performed on canine cadavers to define the blood supply to the caudal sartorius muscle. The vascular supply to this muscle was segmental with the saphenous artery and vein providing a distal vascular pedicle. Anastomotic channels existed between distal and proximal capillary beds within the muscle belly. This anatomic information was used to determine the feasibility of performing caudal sartorius muscle flaps in dogs. The caudal sartorius muscle was transposed to the medial tibial region in four dogs. The muscle flap was based on a singular vascular pedicle of the saphenous artery and vein. The muscle transpositions were all successful on day 14 as evidenced by gross appearance and results of histologic examination. Grossly, the muscles were well adhered to the recipient sites and were covered by connective tissue. Histologically, the specimens were characterized by viable skeletal muscle fibers, large amounts of granulation tissue, varying degrees of inflammatory response, and small foci of myocyte necrosis (2 cases). Seroma formation was a consistent postoperative complication.

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb00999.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Billroth II gastrojejunostomy was performed with surgical staplers in 6 dogs that were not irradiated and in 11 dogs that subsequently received radiation to the pancreas and proximal part of the duodenum. The dogs were monitored clinically for 135 days and then euthanatized and necropsied. Each gastrojejunostomy site was preserved in formalin and the stomal diameter was measured. No mechanical complications were encountered with the use of surgical staplers and no leakage was observed at the staple closure sites before abdominal closure. All dogs vomited approximately 100 ml of coagulated blood 4 to 8 hours after surgery, and 300 to 400 ml of brown fluid after approximately 24 hours. Vomiting was the most common clinical finding after the first 24 hours. Vomiting was subjectively graded from 1 to 3 with grade 1 representing the least severe problem and grade 3 the most severe. Grade 1 vomiting occurred in 12 of 16 dogs that survived 135 days; in the other four dogs, vomiting was classified as grade 2 or 3. All dogs with grade 1 vomiting had stomal diameters of 1.7 to 2.9 cm (mean, 2.2 ± 0.4 cm standard deviation). Dogs with grade 2 or 3 vomiting had stomal diameters of 2.2 to 4.0 cm (mean, 3.2 ± 0.8 cm standard deviation). The difference was statistically significant (p<0.005). The percentage of weight gained or lost was recorded for each dog. Two nonirradiated dogs gained body weight, whereas the other nonirradiated dogs and all irradiated dogs lost body weight. The overall mean loss of body weight of dogs with grade 1 vomiting was 16.7 ± 12.0% (± standard deviation), compared with 35.5 ± 6.6% (± standard deviation) for dogs with grade 2 or 3 vomiting; the difference was significant (p<0.01).Routinely scheduled clinical laboratory test results were within normal limits in nonirradiated dogs. Clinical problems other than vomiting and weight loss were anorexia, gastric dilatation, and diarrhea. One nonirradiated dog died on day 56 after rupture at the gastric stump staple

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb01000.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

A retrospective study of 14 dogs with one or more acetabular fractures stabilized with an acetabular plate was conducted. Twelve of the 14 dogs had additional orthopedic injuries. Follow‐up was longer than 6 months. Eleven dogs were evaluated by assessment of radiographs, lameness, mid‐thigh circumference, coxofemoral joint range of motion, crepitus, and pain. Varying degrees of osteoarthrosis were noted radiographically at follow‐up. Ten of 12 dogs examined had occasional or no clinical lameness. In 10 of 12 dogs, mid‐thigh circumference was less on the limb that sustained the acetabular fracture. Nonunion was diagnosed in one plated acetabulum in which two screws had broken. A return to normal or nearly normal function was observed when there were no more than two orthopedic i

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb01001.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Physical and clinicopathologic findings from six cows with proximal duodenal obstruction (PDO) and 58 cows with abomasal volvulus (AV) were compared retrospectively. Many of the physical signs were similar in cows with PDO and cows with AV, but the two conditions differed in the type of abdominal distention, and in the findings from rectal examination and abdominal auscultation. Cows with PDO had significantly lower mean values for serum sodium (Na+) and chloride ion (Cl‐), and higher mean values for plasma bicarbonate [HCO3], base excess, carbon dioxide pressure (pCO2), serum phosphate, urea nitrogen, and total protein than AV affected cattle. Cows with PDO showed hyperglycemia (range, 263–990 mg/dl; mean, 618 mg/ dl) of unexplained etiology that was significantly higher than blood‐glucose concentrations in AV cows (mean, 178 mg/dl). Although all AV cows with anion gap values greater than 32 mEq/l died; PDO cows with equally elevated anion gap survived. The anion gap elevations in PDO and AV cows resulted from accumulation of different anions. Although the site of obstruction of aborad flow of ingesta is similar in both disease conditions, the differences in physical and clinicopathologic findings appear to reflect differences in the degree of reticulo‐omasal orifice obstruction and the degree of abomasal vascular com

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb01002.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

Interstitial pressure and pH in the dependent biceps femoris muscle were measured in anesthetized, laterally recumbent horses. The mean (± standard deviation) interstitial pressure in 10 horses was 19.70 ± 0.15 mmHg in the 30 to 180 minute interval after induction of anesthesia. Pressures of this order have been associated with reduction in muscle perfusion. Mean (± standard deviation) interstitial pH in six horses decreased from 7.07 ± 0.30 to 6.73 ± 0.21 between 45 and 150 minutes of anesthesia. These results indicated the presence of circulatory compromise to intracompartmental struct

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1988.tb01003.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY