ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01585.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

SUMMARYThree cases of esophageal reflux occurred, one case resulting in perforation of the esophagus. Diagnosis was based on dysphagia, excessive drooling, contrast radiography and surgical findings. Based on known pathophysiological information, it is suggested that the combination of preoperative fast, general anesthesia, dorsal recumbency with head lowered and ovariohysterectomy can all contribute towards reflux of gastric juice into the esophagus. The surgeon can best avoid this rare surgical complication by maintaining the patient in the horizontal supine position.

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01586.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACTAcute gastric dilatation and volvulus with dilatation were produced in 11 dogs anesthetized with halothane. Blood samples were taken during these procedures for biochemical analyses.Serum potassium did not change significantly during the experimental procedure, but there was a significant increase (p<0.05) after release of the dilatation with volvulus. Renal function was impaired with significant increases (p<0.05) in the serum concentration of urea nitrogen, phosphorus, and creatinine. Evidence of cellular damage was reflected by a significant elevation (P<0.05) in glutamic‐oxaloacetic transaminase activity. Serum glucose concentration increased significantly (P<0.05) during experimental gastric dilatation and dilatation with volvulu

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01587.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01588.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01589.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01590.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

SUMMARYA painful neuroma occurs following 25% of routine equine neurectomies unless special neurosurgery is done. There are at least five other complications that one may encounter: (1) A change of gait such as stumbling or forging has been noted, especially when the neurectomy has been done in one leg; (2) A vascular compromise has been found if there had been any complications in wound healing or excessive tissue insult. Excessive scar formation surrounding both the digital vein and artery can compromise the blood supply to the foot. When the posteriod digital nerves are severed the autonomic nerves are also interrupted. This results in a vasodilatation which may be responsible for faster hoof growth; (3) If the navicular bone had undergone osteolytic changes before the neurectomy it may fracture as soon as the horse starts to use the foot; (4) The deep flexor tendon may rupture where it passes over the navicular bone. This is especially true where adhesions between the bone and tendon were present; (5) Infections in the sole, bulbs of heel, frog, navicular bursa or coffin joint often go unattended because the horse does not show a lameness.

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01591.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

SUMMARYSeven dogs with renal allografts were studied to: (1) determine the practicality of the procedure for the treatment of end stage kidney disease in small animal medicine, and (2) measure allograft function to permit evaluation of immunosuppressive drug dosage to prevent rejection.Infection (bacterial nephritis, pneumonia, pleuritis), drug toxicity (bone marrow depression, liver degeneration and/or necrosis), and rejection of the transplants were the consistent problems.No objective measurement which would permit accurate determination of immunosuppressive drug dosage was found.Polyuria in the transplanted animals was attributed to failure to develop the interstitial osmotic gradient essential for the allografts to respond to antidiuretic hormone. Polydipsia probably was compensation for the polyuria.The results would indicate that until a major immunological breakthrough occurs in tissue transplantation, the clinical placement of a renal allograft in the dog for long term function is not practical.Prolonged function of the renal allograft has been accomplished in the dog using immunosuppressive drugs, suggesting that the procedure can be utilized for the treatment of end stage renal disease in this animal.18Immunosuppressive drugs have inherent toxicities, of which bone marrow depression, liver and gastrointestinal tract damage are most notable.5,18,23Ideally, minimal immunosuppression is desired to avoid drug toxicity, maintain some degree of immune competence to reduce chances of serious, if not fatal infection, and yet allow the transplanted kidney to survive in a hostile immune environment.22There are no good measurements to determine the immunological status of patients on immunosuppressive therapy,22consequently, such treatment is emperic; based on experimental and clinical experience.13,18Although the dog is a common model for renal allograft investigations,15,18there is limited information in the veterinary literature 3.5.6,11,14 concerning the experience of veterinary clinicians and their attempts to maintain the renal homograft.This report summarizes the author's experiment with renal transplants in the dog.

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01592.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

SUMMARYA retrospective case history study of acute gastro‐intestinal disease in the horse was undertaken to determine: 1) if a statistically significant age, sex, or breed distribution existed; 2) if a correlation existed between duration of clinical signs and surgical complications; and, 3) if the lesions causing the signs significantly altered surgical prognosis. Significant age, sex and breed distributions existed. Duration of clinical signs ranged to 5 days with a definitive time trend existing for surgical correction of strangulating colics. Surgical correction was successful only within 24 hours of the appearance of clinical signs. Surgical prognosis for specific intraabdominal lesions ranged from 20% survival with strangulation obstructions to 84% with impaction.Differential diagnosis in horses with signs of acute abdominal pain is difficult, and techniques available for this purpose are limited.3,7,8Differentiation of specific lesions is necessary because the prognosis varies greatly with each, and the choice of treatment used depends on the nature of the lesion.1Knowledge of significant age, sex, or breed related distributions would aid differential diagnosis. There are few epidemiologic reports available for use in the clinical management of these cases.4A recent report has dealt with the relative incidence of various types of intestinal obstructive diseases in the horse.7The purpose of this retrospective case history study of gastrointestinal disorders in the horse was to determine:1. If a statistically significant age, sex or breed distribution existed for all or specific lesions;2. If a correlation existed between duration of clinical signs and surgical survival; and3. If the lesions causing the clinical signs significantly altered surgical prognosi

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01593.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

ISSN:0161-3499    

DOI:10.1111/j.1532-950X.1975.tb01594.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY