摘要:

A four-year retrospective review of 55 patients with disseminated infections from Neisserin gonorrhoene revealed that this complication occurs in young adults, with a predominance in women (80%). The most common manifestation of disseminated gonococcal infection was arthritis, which occurred in 47 patients (85.5%). The second most common manifestation of disseminated gonococcal infection was dermatitis, which occurred in 33 patients (60%). A thorough history, a careful physical examination, and a high index of suspicion are essential for the diagnosis. Disseminated gonococcal infection can be confirmed by isolation of gonococci from potential sites, including urethra, cervix, rectum, oropharynx, and blood. Early diagnosis and adequate therapy are necessary to prevent serious complications. The role of the gynecologist in preventing, diagnosing, and/or treating this disorder is emphasized.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

This study reports the results and complications of operation for 85 patients with diverticulum of the urethra. The technique for surgical excision and the factors necessary for successful repair are described. The follow-up period was from 2 to 15 years. Seventy patients (82%) experienced immediate and complete relief. A clinically significant postoperative complication—urethrovaginal fistula—occurred in one patient; clinical evidence of urethral stricture was not encountered. Delayed complications eventually occurred in 14 patients: Recurrent urinary tract infection (2), urethral pain syndrome (2), urinary incontinence (2), and recurrent diverticulum (8). Many of these were continuations or recurrences of the chronic infectious entity rather than complications related to urethral diverticulectomy.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Histologic sections from cervical and vaginal biopsies showing dysplasia in 37 women exposed to diethylstilbestrol (DES) in utero were stained for human papillomavirus structural antigens using an immunoperoxidase technique. Forty-three percent of the lesions had detectable papillomavirus antigens. These findings indicate that a significant proportion of cervical dysplasia observed in DES-exposed progeny is associated with papillomavirus infection.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

The treatment of 224 patients with invasive squamous cell carcinoma of the vulva over a 20-year interval at the Mayo Clinic resulted in an overall survival rate of 75%, compared with 89% for age-matched controls. For patients with stage I disease, 5-year survival was 90%; for those with stages II, III, and IV, it was 81, 68, and 20%, respectively. A precipitous decline in survival rates was noted when metastases to regional nodes were encountered, when lesion size was more than 3 cm, arid when histologic dedifferentiation exceeded grade 2. Incorrect clinical staging efforts were observed in 25% of the cases, so the necessity for surgical staging was apparent.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Two hundred patients with cervical intraepithelial neoplasia were treated alternately by cryotherapy and carbon dioxide laser therapy on an outpatient basis after appropriate triage with colposcopy, cervical biopsy, and endocervical curettage. Results of treatment were not significantly different from one another, with failure occurring in 7% of patients treated with cryotherapy and 11% of those treated with carbon dioxide laser therapy. The cryotherapeutically treated patients had less pain but more discharge than those treated by the carbon dioxide laser. The laser patients' cervices healed more rapidly than did the cervices treated with cryotherapy. There appears to be no advantage in replacing cryotherapy with carbon dioxide laser therapy.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

At the Royal Women's Hospital Melbourne, treatment of cervical intraepithelial neoplasia has consisted mainly of electrocoagulation diathermy. A random group of 420 consecutive patients attending the follow-up clinic has been studied to assess subsequent cervical function. Long-term follow-up has revealed minimal adverse effects on fertility, parturition, and menstrual function.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Twenty patients were studied with static and cinefluoroscopic intravenous pyelograms to quantitate the morphologic and physiologic ureteral alterations following radical hysterectomy and pelvic lymphadenectomy. More than 87% of the patients in the 48-hour study had ureteral dilatation, which persisted for 7 days in most patients, proximal to the site of pelvic dissection. By 6 weeks after surgery, the dilatation had regressed and pyelograms returned to normal. Transit time from renal pelvis to bladder was doubled at 7 days. An alteration in the character of peristalsis was noted on the cinefluoroscopic studies at 48 hours and at 7 days. The distal ureter appeared as a rigid conduit, and the peristaltic activity was replaced by bolus emptying.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Venous thromboembolism is a leading cause of death and morbidity after extended surgery for early malignancies of the cervix and uterus. Two hundred eighty-one patients who underwent such surgery were retrospectively evaluated for associated risk factors, the incidence of clinically significant thromboembolic complications, and prophylactic value of low-dose heparin and antiembolism stockings. Significant thromboemboli were encountered in 7.8% of patients postoperatively and accounted for the only 4 postoperative deaths. Forty-five percent of patients who developed thromboemboli did so after discharge from the hospital. The preoperative risk factors found to be associated with thromboembolism, in order of statistical significance, were weight in excess of 85.5 kg, advanced clinical stage of malignancy, and radiation therapy within 6 weeks of the operative procedure. Low-dose heparin therapy and the use of antiembolism stockings as preventative measures did not appear to reduce the incidence of thromboembolic complications. A prospective study will be necessary to evaluate definitely the effectiveness of various therapeutic modalities on thromboembolism in gynecologic oncology patients.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

High doses of the oral progestin megestrol acetate were used to treat patients with ovarian cancer who had suffered relapses following conventional therapy. In all but 2 of these patients, second-line drugs or other additional therapeutic measures had been tried before resorting to the highdose oral progestin. The response of 24 patients is the subject of this report. Megestrol acetate proved to be useful for those who were able to take oral medication and who failed to respond to other forms of therapy.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

In this study, the author reports the levels of serum lactic dehydrogenase in patients with ovarian dysgerminoma. The results of previous studies have shown that serum lactic dehydrogenase is elevated in patients with primary ovarian carcinoma but not in those with other pelvic tumors, benign or malignant. In the present study, serum lactic dehydrogenase levels were highly elevated before patients were treated for ovarian dysgerminoma and sharply reduced to normal levels after treatment. This finding may demonstrate an important tumor marker in the diagnosis and treatment of ovarian dysgerminoma.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID