摘要:

Lecithin/sphingomyclin ratio (L/S ratio) in amniotic fluid has gained wide clinical acceptance as an index of fetal lung maturity. We determined L/S ratios of amniotic fluids centrifuged at various “g-forces.” Our studies demonstrate that the L/S ratio value is highly dependent on the g-force used to prepare the fluid. We recommend standardization of the g-force, time, and temperature used in preparation of the amniotic fluid for L/S ratio determination.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

This study reviews 27 patients with positive OCTs who were subsequently allowed a trial of directly monitored labor. Of these, 19 patients (70%) developed FHR signs of fetal distress and 8 (30%) tolerated labor without late decelerations. These patients were evaluated for signs of fetal reactivity (acceleration of the FHR associated with fetal movement or contractions) during the OCT. Those with a reactive pattern during the OCT (IS patients) uniformly had a good fetal outcome (unless there was birth trauma or premature delivery), but 8 of these IS patients showed fetal distress during monitored labor. If the positive OCT was associated with a nonreactive baseline FHR recording, a trial of labor uniformly resulted in FHR signs of fetal distress. It is therefore concluded that a patient with a nonreactive positive OCT is unlikely to tolerate subsequent labor without fetal distress.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

Until now, no statistical data have been available on the significance of the frequency of FHR oscillations. In order to evaluate the relation between oscillation frequency and neonatal outcome, the last 30 minutes of 812 FHR records were analyzed with respect to the number of oscillations per minute only. Close correlations were found between slow oscillations below 2 per minute and the arterial cord pH as well as the Apgar scores after I and 5 minutes, respectively. No relation could be established between any oscillation frequency above 2 per minute and the measures of the neonatal outcome. In discussing the results, slow oscillations arc suggested to be identical with the sinusoidal FHR. Emphasis is made that for an appropriate pattern recognition, (rue heat-to-heat recording is required, avoiding any averaging procedure.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

The ability to measure directly human parathyroid hormone (hPTH) and ionized calcium (Ca++) is of fundamental importance in understanding their interrelation in pregnancy and the newborn. hPTH and Ca++ progressively increase throughout pregnancy. Since Ca++ is the direct determinant of hPTH levels, a different “set point” appears to be operative throughout pregnancy. The newborn infant, on the other hand, has higher serum Ca++ levels than its mother, and the infant's plasma hPTH is suppressed to undetectable or low levels. Ca++, total serum Ca, magnesium, and phosphorus are all significantly elevated in the serum of the infant compared to the serum of the mother at delivery. An active transport mechanism of all these minerals appears to be operative and lowers the maternal serum levels at the termination of labor in relation to serum levels in the third trimester of pregnancy.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

Placental positions in 214 patients scheduled for genetic amniocentesis were reviewed. Forty-five percent were found to have ultrasound findings of a low-lying placenta or partial or total placenta previa. At term, none of these patients required intervention for bleeding or placenta previa. Parity of 4 or more, but not age, correlated with an increased incidence of partial or total placenta previa, but not with a low-lying placenta. Low-lying placenta or placenta previa may be a normal variant in early pregnancy, suggesting that failure of the placenta to relinquish this position can result in an abnormally implanted placenta at term.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

To test the hypothesis that the increased incidence of hyaline membrane disease in second-born twins is related to acidosis at birth, umbilical arterial [H+] was measured in 26 sets of premature twins. Although overall Twin B had a lower Apgar score than Twin A, there was no difference in their [H+], If the delivery interval was prolonged over 8 minutes then Twin B infants were more acidemic and had lower Apgar scores. Infants with hyaline membrane disease had lower Apgar scores, but were not more acidemic than infants without respiratory distress. Our data suggest that acidosis at birth is not an important factor in the development of hyaline membrane disease.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

Pregnant rats were injected daily with 2, 4, or 20 mg/kg of Imuran from the first day of gestation until sacrificed on Days 6-12. Gravid uteri, as well as maternal organs, were removed and examined histologically. According to the histologic findings, the treatment with the high dose of 20 mg/kg/day Imuran induced injuries to the blastocyst. Starting from Day 8, the trophoblastic layer lost its continuity and maternal blood invaded into the blastocystic cavity resulting in destruction of embryonic tissues. This degeneration progressed until evident resorption on Day 12. Smaller doses, such as 2 or 4 mg/kg of Imuran, did not result in early trophoblastic damage. The effect seemed to be the result of the antimetabolic effect of Imuran acting on the proliferating trophoblast through the maternal blood.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

Five patients with symptomatic postoperative introital or vaginal stenosis were evaluated and treated. In each case simple operative correction, utilizing basic plastic surgery principles, was successful. The five operative techniques as used alone and in combination arc described. Though postoperative stenosis of the vagina and/or introitus is relatively uncommon, the resulting disability is such that every gynecologic surgeon should be familiar with the problem and solution. In most cases simple surgical correction can be successful if the surgeon is familiar with basic techniques and principles.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

A simple and rapid test that correlates with L/S ratios has been developed. By centrifuging fresh, unfrozen amniotic fluids at 2000g for 10 minutes and measuring the optical density at 6S0 nm, correlation with L/S ratios is obtained. Optical density readings of 0. IS or greater correlate 100% with L/S ratios of 2.0 or greater. Optical readings below 0.15 correlate 94% with L/S ratios below 2.0.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID

摘要:

Two patients with endometrial carcinoma containing psammoma bodies are presented. The necessity of distinguishing this neoplasm from an ovarian carcinoma is stressed. The rarity of this finding and its histogenesis are discussed, and the literature on the subject is reviewed.

ISSN:0029-7844    

出版商:OVID    

年代:1977

数据来源: OVID