摘要:

A review was made of histories of 5010 patients delivered by the senior author over a period of 25 years. Of these deliveries, cesarean section was performed in 283 (5.6%). In 218 of these patients, only local field block of the abdominal wall was done prior to the birth of the baby. When local anesthesia was used, 92% of newborn babies cried spontaneously at once. There were -18 premature babies and 7 neonatal deaths, the latter caused primarily by pregnancy complications and secondarily by prematurity. Fetuses already at high risk are most benefited by the use of local anesthesia prior to birth. Many of the patients experiencing this method had second, third, and even fourth cesarean sections with the use of local anesthesia.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Osteogenesis imperfecta during pregnancy presents increased risk in mother and fetus. In addition lo the known skeletal changes', other recently recognized metabolic abnormalities also may lead lo maternal an leis during labor and delivery. A discussion of risk factors and their management is presented. The importance of considering the possibility of fetal osteogenesis imperfecta is stressed and cesarean is presented at the method of choice for delivery. Important genetic factors including the lack of correlation between the severity of involvement of parent and offspring and the use of pyrophosphate analyses are discussed. An illustrative case is presented.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Progesterone concentrations in 2 full-term normal placentas, molar tissue from 3 cases of hydatidiform mole, and ovarian tissue from a theca lutein cyst of hydatidiform mole were measured by competitive protein binding. Sephadex LH-20 column chromatographic separation of extracts from these tissues showed that, in placental and molar tissue, 85 to 95% of the extracts were progesterone and very small amounts of 20α-dihydroprogeslcrone and 17α-hydroxyprogesterone. The concentrations of progesterone in the placentas were 368.8 and 317.2 ng/g tissue, respectively, while in molar tissue the concentrations were 2474.5, 1974.6, and 4146.0 ng/g tissue, respectively. Progesterone concentration in ovarian tissue was between 1121.2 and 1440.9 ng/g tissue. It is suggested that the high concentration of progesterone in molar tissue reflects functional capacity of the abnormal trophoblast in progesterone synthesis and accumulation of progesterone due to absence of a fetus. The lower concentration of progesterone in the ovary in molar pregnancy would appear to suggest that the ovary is a secondary source of progesterone in molar pregnancy.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The English language literature for the years 1935-1972 was reviewed to assess the effect of pelvic exenteration on vaginal embryonal rhabdomyosarcoma. Twenty-one cases were determined eligible for review. Tumor was confined to the vagina in 8 cases and extended beyond the vagina in 13 cases. Treatment by pelvic exenteration was found to be a relatively ineffective means of curing patients with tumor extending beyond the limits of the vagina. Recent evidence from the literature indicates that better results can be obtained by coordinated treatment, ie, surgery, radiation therapy, and/or chemotherapy, than by surgery alone.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Twenty-three cases of malignant melanoma of tile vulva recorded at Roswell Park Memorial Institute over a 36- year period have been reviewed. The findings confirm those of earlier series that these lesions tend to occur in postmenopausal Caucasians and most commonly originate on the labia minora and clitoris. Twenty of 23 patients were treated with therapy more conservative than radical vulvectomy and regional node dissection, with a resultant 25% 5-year survival and 10% 10-year survival among eligible patients. The fact that 12 of 1-1 recurrences were on the vulva or in inguinal nodes argues for primary surgical removal of these structures. No patient in this series with a lesion greater than 2 cm or with clinically positive groin nodes survived 5 years. According to the literature, very few patients with groin node involvement have survived, even with radical surgical therapy, and a combination of therapeutic modalities in treating these patients is recommended.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The literature reflects a poor prognosis for women with endodermal sinus tumor. Two women with this neoplasm, 1 having stage IA and the other stage IIB disease were treated for 1 year postoperatively with a combination of actionmycin.D, 5-fluorouraciI, and cyclophosphamide. Each had therapy discontinued after a negative second laparotomy and 15 and 21 months later arc without recurrence. It is suggested that this drug regimen is a beneficial adjunct to surgery in the treatment of endodermal sinus tumor.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

In this study, C3H/HeJ female mice received all intraperitoneal injection of mammary tumor suspended in saline. After 14 days, the presence of mammary neoplasm was detected by a significant change in the cytodifferential counts of aspirated peritoneal fluid. Previous studies suggest that ovarian cancer can he detected in mice and in women by the characteristic changes produced in abdominal cellular fluid distribution.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The aim of this work was 10 document the validity and usefulness of progesterone determination instead of endometrial biopsies as evidence for ovulation within a menstrual cycle. The presence of progesterone in amounts greater than 2 ng/ml of plasma was always associated with a secretory endometrium, ie, the endometrium was matured beyond cycle day M as diagnosed by classical histologic dating. The remarkable simplicity of quantitating Inteal phase progesterone levels by this radioimmunoassay warrants their extended use for evaluating the physiology and the pathology of the corpus luteum.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Data arc presented from an investigation of the association of presenting complaints with gonococcal infection in females. seeking primary care in an urban emergency room. Over 27C£ of patients in the study had cultures positive forNeisseria gonorrhoeae(GC). The GC positivity rates which were significantly higher than expected were found in patients with abnormal uterine bleeding, urinary tract symptoms, and cervicitis, as well as acute PID. Clinical findings suggest an etiologic role for the gonococcus in the pathogenesis of these disorders. Where the incidence of gonorrhea is high, new approaches in the management of patients with these presenting complaints are necessary in order to prevent the more serious complications of gonorrhea and further spread of the disease.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Three cases or coccidioidomycosis of the female genital tract are reviewed. The diagnosis was made by laparotomy in 2 patients who presented with tender adnexal masses, and by endometrial curettage in a third patient with disseminated coccidioidomycosis. Hysterectomies were performed in all 3 patients; 1 had a bilateral salpingo-oophorectomy and the others a bilateral salpingectomy and unilateral oophorectomy. Two patients received chemotherapy with amphotericin it. One patient died '1 years after her operation from disseminated and meningeal coccidioidomycosis. In a female patient who has resided in an endemic region and who presents with pelvic pain of obscure origin, unexplained infertility, a menstrual disorder, or a chronic, refractory pelvic inflammatory disease, genital coccidioidomycosis should be considered in the differential diagnosis.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID