摘要:

Serum gentamicin levels were measured by agar diffusion bioassay in 38 patients undergoing treatment with clindamycin- gentamicin for post-cesarean endomyometritis. Patients received intravenous gentamicin in a dose of 1 mg/kg actual body weight every eight hours. All trough levels were less than 1/ig/ml. The mean 30-minute postinfusion level was 5.78 ± 2.43 /tig/ml (mean ± SD). The range of postinfusion concentrations was 1 to 12 jug/ml. Postinfusion concentrations were less than 5 /ug/ml in 13 patients, but none of these individuals experienced a clinical failure of antimicrobial therapy. There were no statistically significant differences in mean age, weight, hematocrit, serum creatinine, estimated creatinine clearance, or administered dose in patients with therapeutic gentamicin levels and patients with apparent subtherapeutic levels. The authors conclude that postinfusion gentamicin concentrations fluctuate widely in obstetric patients receiving 1 mg/kg/dose and that apparent subtherapeutic postinfusion levels still may be clinically efficacious, depending upon the antimicrobial susceptibility of the infecting microorganisms.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Although ultrasonically detectable placental changes have been correlated with fetal maturity, the relative incidence of each placental grade at various gestational ages has not been known. During a one-year study period, placental grading was evaluated in 1709 scans performed at 27 weeks' gestation or after. At 40 weeks' gestation or beyond, only about 20% of placentas had extensive calcification (Grannum grade 3). Significant placental calcification was rarely seen before 37 weeks' gestation. Placental grading could not be used to predict postmaturity. The incidence of fetal distress in labor was found to be increased with postmaturity as well as with other pregnancy complications that give rise to premature placental senescence, rather than with grade 3 placentas per se.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

In the People's Republic of China one of the most widely used methods of second-trimester abortion is the intraamniotic injection of ethacridine (Rivanol). Intraamniotic ethacridine produces fetal death, a fall in maternal urinary estriol excretion, and a rise in prostaglandin levels. Although the induction time is longer than that usually seen with prostaglandins, the method is not ordinarily associated with vomiting, cervical injury, or the delivery of a live fetus. In a series of 10,302 cases, the success rate was 96.4% and the incidence of associated complications was low.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Many of the components of amniotic fluid have been found to be valuable in prenatal diagnosis; however, the presence of erythrocytes is usually considered undesirable. The authors have used buoyant density centrifugation on 96 amniotic fluid specimens from 70 subjects to isolate small numbers of erythrocytes from a majority of these specimens. Through immunofluorescence, these specimens were found to have higher levels of fetal hemoglobin-containing cells than the adult, indicating that the erythrocytes were at least in part fetal in origin. Thus, erythrocytes present in amniotic fluid could also be used in prenatal diagnosis.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Vaginal reconstruction was performed in 14 patients who had developed vaginal stenosis secondary to extensive pelvic fibrosis after pelvic radiation therapy (12 patients) or prior vaginal reconstruction (2 patients). Sixteen procedures were performed using a split-thickness skin graft. All patients had satisfactory vaginal restoration, and 12 patients reported good vaginal function. No fistula developed as a result of the operative procedure, but one patient later developed a rectovaginal fistula resulting from tumor recurrence. Successful vaginal reconstruction can be achieved even years after initial therapy in patients who develop an obliterated vagina from previous radiation or surgery.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Labor was induced by amniotomy at 34 weeks' gestation because of preeclampsia in a woman with a recent ruptured cerebral aneurysm prior to corrective neurosurgery. Neither labor nor vaginal delivery caused neurologic injury to the mother. Subsequent neurosurgery was successful and both mother and infant continued to do well several months later. These outcomes support management advised in the literature in circumstances not previously reported.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Two cases of successful pregnancy in patients with a ventriculoperitoneal shunt are presented. Both patients experienced shunt malfunction early in the third trimester which was apparently related to anatomic changes in the abdomen associated with pregnancy. All symptoms resolved with conservative management. The obstetric and neurologic management of such patients is discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

The use of intraperitoneal dextran at the conclusion of a gynecologic surgical procedure to prevent postoperative adhesions has increased recently. Although anaphylactic reaction to dextran administered intravenously is well documented, the authors report such a reaction after intraperitoneal administration. The delayed appearance and the continuation of the undesirable reaction until the intraperitoneal reservoir of dextran was removed by means of a culdocentesis are noteworthy. Physicians should be alerted to this potential complication.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Necrotizing fasciitis and progressive bacterial synergistic gangrene are two infrequently reported diseases in the gynecologic literature. The author reports 2 cases highlighting the many similarities and some important differences between these clinical entities. Diabetes mellitus and arteriosclerosis predispose women to both diseases. Aggressive antibacterial and surgical treatment is imperative.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

An unusual presentation of metastatic vaginal carcinoma is reported. A patient with primary squamous cell carcinoma of the vagina presented with symptoms of acute congestive heart failure, and pulmonary lymphangitic spread of the squamous cell carcinoma was found. The use of a Swan- Ganz catheter and the possible efficacy of transbronchial biopsy are discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1983

数据来源: OVID