摘要:

The cervical-vaginal flora of 21 women with invasive cervical cancer was determined. The cultures yielded polymicrobial growth with anaerobic organisms predominating. As compared with other studies of vaginal flora, the cancer patients were found to have a decreased frequency of isolation of aerobic lactobacilli,Staphylococcus epidermidis. and enterococci, and an increased frequency of isolation ofEscherichia coliand Bacteriodes species. The composition of the anaerobic vaginal flora in these patients is similar to that described for immunosuppressed renal transplant patients.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

This project was designed to determine if the presence of fibrin degradation products (FDP) in the blood are of value in the prcoperativc evaluation of patients with pelvic masses. This study comprised 120 consecutive patients who were evaluated for a diagnosis of pelvic mass, ovarian cyst, or ovarian carcinoma. A blood sample was drawn from each patient and fibrin degradation products were determined utilizing the Thrombo-Wellcotest. Platelet counts and partial thromboplastin time (PTT) were also determined on each patient. Ovarian carcinoma was present in 17 (14.2%) of the patients. The FDP was found in the serum of 16 (94.1%) of the patients with ovarian carcinoma. One (5.9%) of 17 patients with ovarian carcinoma had a negative FDP (<10 mg/ml). Eleven of the 120 patients (9.2%) had a positive FDP with no demonstrable etiology. A sample of fluid was obtained from two cystic ovarian carcinomas and when analyzed for FDP both samples were strongly positive.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

A 23-year-old female with clinical signs of excessive androgen and estrogen production was found to have a gonadal stromal tumor. The clinical symptoms correlated well with steroid hormone values in ovarian vein blood and ovarian cyst fluid of the ovarian tumor. Ovarian vein blood draining the ovarian tumor measured as follows: estrone, 162 pg/ml; estradiol, 1688 pg/ml; progesterone, 9.6 ng/ml; testosterone, 9775 ng/100 ml; and di-hydrotcstostcrone, 2905 ng/100 ml. The ovarian cyst fluid produced higher estrogen and lower androgen values compared with ipsilateral ovarian vein blood. Peripheral levels of immunoreactivc testosterone ranged from 210 to 244 ng/100 ml. It is concluded that excessive androgen and estrogen production may arise from a gonadal stromal tumor that has been previously classified as a purely vjrilizing ovarian tumor.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Symptoms and signs of interstitial pregnancy cannot be differentiated from symptoms and signs of other ectopic pregnancies. Unruptured interstitial gestations are usually diagnosed incidental to the work-up of a suspected ectopic gestation. Unlike some teaching, a characteristic pelvic mass was palpable in 3 of 4 cases. Incomplete induced abortion helped in diagnosing 2 cases. Ultrasound and laparoscopy will aid in establishing the correct diagnosis.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

A case is presented that suggests that intrauterine transfusion carries the risk of sensitization to red cell antigens other than Rh0+In this case intrauterine transfusions of Jk11positive red cells were followed by the appearance in the mother's serum of anti-Jk, an antibody known to cause hemolytic disease of the newborn. The use of the mother as a donor of red cells for her fetus will circumvent the problem of further maternal sensitization.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

A 21-year-old white female with short stature, cubitus valgus, multiple cutaneous nevi, and no other major features of the Turner syndrome is described. She had normal secondary sex development and menses. She recently completed a normal pregnancy with delivery of a normal male infant. Postpartum endocrine studies were normal. All cells examined from blood, skin, uterus, and both ovaries had a 45, X karyotype. She is the sixth reported monosomy X patient to achieve pregnancy. A literature review indicates increased fetal wastage (22 of 46 pregnancies) and increased chromosomal errors in the offspring (8 of 26 liveborn infants) of patients with a 45,X cell line. Three cases of trisomy 21 occurred in these infants. Amnioccntesis and prenatal diagnostic studies are indicated for women with a 45,X chromosome constitution. The pathogenesis of the Turner syndrome is considered in relation to these findings.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Abruptio placentae occurs once per 120 deliveries, but accounts for 15–25% of all perinatal mortality. Several series in the literature suggest that an abnormal fetal-maternal relationship exists in patients with abruptio placentae weeks prior to the actual placental separation and that the separation is only the terminal event. A review of the literature and an analysis of 388 cases of abruptio placentae from the US Navy Coding System were undertaken. It was found that approximately 75% of fetal deaths occurred more than 90 minutes after admission to the hospital and almost 70% of all perinatal mortality occurred in infants who were delivered more than 2 hours from the time of diagnosis. Delivery by cesarcan section improved survival in those infants weighing 1500 g or greater and reduced perinatal mortality as much as fourfold in some reports. A prospective study is proposed which would compare two methods of management of this condition.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Learning proper techniques in physical examinations is mandatory for a physician. Although students may examine each other in early training, examination of the female pelvis does not readily conform to this reciprocity. A randomized study was conducted, comparing teaching methods utilizing professional patients or plastic models. Training on a professional patient significantly increased a student's chance of palpating one or both ovaries, reduced the student's anxiety about performing a pelvic examination, and may have improved the student's gentleness. Costs of the professional patient method were minimal. It is recommended that teaching pelvic examinations with the professional patient replace teaching on the plastic model.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

A total of 410 colposcopic examinations were performed on 188 female cebus monkeys that were under study to determine the oncogenic potential of herpes simplex virus type 2 in this genus. A split-cone vaginal speculum was developed that permitted good observation of the vaginal cervix in the cebus monkey. The cervical anatomy of cebus monkeys was found to differ from that of humans in that the surface of the animal cervix was more papilliform, with thinner squamous epithelium, and the squa-mocolumnar junction lay within the cndocervical canal. Therefore, the ability to detect abnormalities in the cervical epithelium by colposcopic examination in the cebus monkey was restricted to vascular changes in the squamous epithelium. After 100 examinations, several vascular patterns were distinguishable and interpretations of these patterns were compared with cytologic findings on the same animals. Findings by both cytology and colposcopy were mild in nature; no carcinoma was detected. Colposcopic and cytologic findings correlated at a level of 84%. More abnormalities were detected with colposcopy than with use of cytologic techniques.

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID

ISSN:0029-7844    

出版商:OVID    

年代:1978

数据来源: OVID