摘要:

The effectiveness of the carbon dioxide laser was evaluated in the treatment of penile, anorectal, and urethral condylomata acuminata in 40 men. All but six cases of urethral condylomata were prior conventional treatment failures. Postlaser follow-up ranged between one and two years, with an average of 16 months. No patients were lost to follow-up. Postlaser recurrence rates were 7.5%. No postoperative complications occurred in this series. Carbon dioxide laser is highly successful for treating persistent and/or extensive urogenital and anal condylomata in the male patient.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

Data available to the World Health Organization on frequency of cancers of the cervix in developing countries are incomplete and fragmentary. There are many indications that cancers of the cervix represent problems of a public health dimension in these countries. With a few exceptions, screening efforts are low-volume institution-based cytology services reaching limited segments of the female population. On the other hand, the recognized risk factors for cancer of the cervix are widely prevalent in developing countries. Cultural and educational constraints often bar women from seeking medical attention. Diagnostic and treatment facilities, particularly radiotherapy, and all levels of trained staff have been insufficient to permit screening programs for cancers of the cervix. Development of future programs must ensure their integration into existing health infrastructures.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

Mass screening programs for cancer of the cervix were introduced at different times and to different extents in the Scandinavian countries. Iceland and Finland introduced nationwide screening programs in the early 1960s. Ten years after their introduction, marked reductions in incidence and mortality of invasive cervical cancer were observed, seen specifically in the age groups to which screening was targeted. In Sweden and Denmark, mass screening was introduced on a county basis, and changes in incidence and death rates from cervical cancer were recorded which reflected the degree to which organized mass screening had been introduced. These data demonstrate that mass screening scheduled every two to five years can reduce the incidence of invasive cervical cancer by 80%. No evidence is available from Scandinavia that more frequent screening reduces the risk further.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

Patients (358) with advanced (FIGO stages III and IV) or recurrent endometrial cancer were treated with one of two regimens: 1) melphalan and 5-fluorouracil daily for four days, repeated every four weeks with megace daily for eight weeks and 2) adriamycin, 5-fluorouracil, and cyclophosphamide, intravenous bolus every 21 days with megace daily for eight weeks. All patients were randomized except for 63 with known cardiac disease who were assigned to regimen 1 (to avoid adriamycin) and studied separately. Stratification was effected for performance status, history of previous progestational therapy, presence or absence of measurable disease, and stage of disease. The objective response rate in those with measurable disease was 36.8% in both groups; 36.8% of each group had stable disease, and only 26.4% progressed on treatment. Response was unaffected by site of recurrence, time to first recurrence, presence or absence of previous treatment by progestational or radiation therapy, or age. Grade of tumor and performance status did affect response, although 44 of 57 objective responders had undifferentiated tumors. The two combinations achieved response rapidly, required careful supervision, and were especially useful in treating patients with usually poor prognostic features.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

The effect of estrogen, progesterone, testosterone, and hydrocortisone on prostacyclin, thromboxane, prostaglandin E, and prostaglandin F from cultured endothelial cells was investigated. No effect was found on prostacyclin, prostaglandin E, and prostaglandin F. Estrogen increased the release of thromboxane. The significance of this finding with regard to venous thrombolic events associated with estrogen use is discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

Renal transplantation has been very effective in the treatment of end-stage renal disease. Over 750 cases of successful pregnancies in these patients have been reported, and only 15 patients with sickle cell disease (homozygous hemoglobin S) have had renal allografts. The present study documents the first case of a successful pregnancy in a patient with sickle cell disease and renal transplantation. The combined complications increase the risks in view of the susceptibility of certain vital organs in pregnancy. Careful multidisciplinary management enhances successful outcome.

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0029-7844    

出版商:OVID    

年代:1984

数据来源: OVID