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1. |
Rising Expectations—A New Dimension |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 383-391
RICHARD SCHMIDT,
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ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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2. |
Gonadotropin Secretion and Hypothyroidism |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 392-396
GLENN BUCHANAN,
DONALD TREDWAY,
JOEL PITTARD,
THOMAS DAANE,
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摘要:
Hypothyroidism is generally associated with hypogonadotropism. Occasionally, however, increased gonadotropin concentrations are encountered. The mechanisms, presumably hypothalamic, which determine the gonadotropin shift are unclear. A case report of hyperprolactinemic hypothyroidism with associated hypergonadotropism is presented. The previous literature is reviewed. It appears that hypothyroidism is generally associated with a decrease in the gonadotropin secretion. However, hypothyroidism with exaggerated hTSH secretion and hyperprolactinemia can be associated with increased gonadotropin secretion.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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3. |
Mixed Gonadal Dysgenesis Without Virilization |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 397-400
ELI ADASHI,
MARTIN FARBER,
HOMA SAFAII,
GEORGE MITCHELL,
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摘要:
A 19-year-old phenotypic female with primary amenorrhea and 45X,0/46X,Y chromosomal mosaicism was found to have asymmetrical gonadal dysgenesis. Her lack of virilization precludes her precise categorization in the current nomenclature of gonadal dysgenesis and she is considered a unique variant of the syndrome of mixed gonadal dysgenesis.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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4. |
Diagnosis of Pregnancy With a Radioreceptor Assay for hCG |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 401-406
SUBIR ROY,
THOMAS KLEIN,
JOSEF SCOTT,
OSCAR KLETZKY,
DANIEL MISHELL,
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摘要:
A new serum assay for human chorionic gonadotropin, the radioreceptor assay (RRA), was compared with three commercial urinary agglutination inhibition pregnancy tests (AITs) in a group of women with suspected early pregnancies and ectopic gestations. The accepted definitions by which a laboratory test is characterized, including clinical sensitivity and specificity as well as predictive value of positive and negative tests and efficiency, were calculated for each test in three different time periods of gestation: less than 7 days, between 7 and 14 days, or more than 14 days after the expected menses had been missed. The results of the study showed that the RRA had greater clinical sensitivity and efficiency than the AITs in cases of both early gestation and ectopic pregnancy. The RRA has the disadvantages of requiring the capability to handle radioactive materials and gamma counter. This test is chiefly useful for those patients desiring early termination of pregnancy and those infertility patients anxious for early confirmation of pregnancy.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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5. |
Conjugated Estrogens and the Overnight Dexamethasone Suppression Test |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 407-409
GARY TREECE,
DAVID MAGELSSEN,
BRUCE FARRISS,
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摘要:
Basal (8:00 AM) serum cortisol levels in peri- or postmenopausal women treated with 0.625 mg daily of conjugated equine estrogens were only slightly higher than pretreatment levels. A 1.25 mg/day dosage resulted in a significant increase in basal serum cortisol levels. In women treated with either dosage, 8:00 AM serum cortisol levels 8 to 10 hours after 1 mg of oral dexamethasone were suppressed to below 5 µg/100 ml, although there was a significant rise in post-dexamethasone serum cortisol levels in those treated with the higher dosage. It is concluded that while replacement dosages of estrogens increase circulating total serum cortisol levels, they do not interfere with the interpretation of the overnight dexamethasone suppression test.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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6. |
Microinvasive Squamous Carcinoma of the CervixDefinition, Histologic Analysis, Late Results of Treatment |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 410-414
JAN SESKI,
MURRAY ABELL,
GEORGE MORLEY,
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摘要:
The surgical tissues and clinical records of 54 surgically treated patients with microinvasive carcinoma of the cervix were retrospectively analyzed. Utilizing a definition that limited microinvasion to a depth of 3 mm, and excluded lymphatic and blood vascular involvement, the incidence of regional metastases in 37 patients for whom lymph nodes were available for study was 0%. Confluence of microinvasion did not imply a greater potential for metastatic spread or a worse prognosis. Lymphatic and blood vascular permeations were associated with nodal metastasis one of four lesions which otherwise were microinvasive. Random cervical biopsy alone was inadequate for the diagnosis of microinvasion. Cone biopsy demonstrated an accuracy of 83% in diagnoses, but failed to eliminate intraepithelial or microinvasive carcinoma in 78% of the hysterectomy specimens. It is concluded that microinvasive carcinoma, as defined in this study, can effectively treated by conservative rather than radical means.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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7. |
Treatment of Advanced Adenocarcinoma of the Endometrium With Melphalan, 5-Fluorouracil, and Medroxyprogesterone AcetateA Preliminary Study |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 415-417
CARMEL COHEN,
GUNTER DEPPE,
HOWARD BRUCKNER,
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摘要:
Combination chemotherapy can produce a rapid and frequent therapeutic effect against advanced endometrial adenocarcinoma regardless of the tumor distribution. A new treatment program is described. Melphalan, 5-fluorouracil, and medroxyprogesterone acetate achieved 6 of 7 objective responses in patients. This result with combination chemotherapy is substantially better than results with single agents or hormones alone and justifies further evaluation of combinations of cytotoxic chemotherapy as part of the initial treatment of choice for patients with advanced endometrial adenocarcinoma.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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8. |
Paraaortic Lymphadenectomy in Gynecologic Malignancies Confined to the Pelvis |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 418-423
GREGORIO DELGADO,
BYUNGKYU CHUN,
HALUK CAGLAR,
FRANK BEPKO,
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摘要:
Eighty-six patients with pelvic malignancies had paraaortic node dissection; 30% had positive paraaortic lymph nodes. At the time of laparotomy, 77 patients had malignancies apparently confined to the pelvis after extensive work-up and histologic examination of tissue biopsies outside the pelvis; 20 (26%) had metastatic cancer in the parasortic lymph nodes. Thirteen of 49 patients with cancer of the cervix, 5 of 18 with uterine cancer, and 2 of 10 with ovarian cancer had positive paraaortic lymph nodes. The value of paraaortic dissection in patients with pelvic malignancies apparently confined to the pelvis is discussed.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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9. |
AdenomyosisA Neglected Diagnosis |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 424-427
TITUS OWOLABI,
RONALD STRICKLER,
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摘要:
Adenomyosis was present in 161 of 1619 consecutive hysterectomy specimens. Adenomyosis coexisted with other pelvic pathology in 97 women and was the only histologic finding in 64 women. Most patients were 35 to 5O years of age, parous, white, had not taken steroid hormones, had not had uterine surgery, and complained of abnormal uterine bleeding and/or pelvic pain. Adenomyosis was most associated with leiomyomata, endometrial hyperplasia and carcinoma, and endometriosis. The clinical signs of uterine enlargement and tenderness were rarely observed. The diagnosis was suspected preoperatively in 10% of women. At surgery, adenomyosis was not recognized in 65% of patients. Adenomyosis is a disease of unknown etiology whose uncharacteristic clinical profile and frequent association with more obvious pelvic pathology make it a neglected diagnosis.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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10. |
Low Morbidity in the Surgical Patient With Group B Streptococci |
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Obstetrics & Gynecology,
Volume 50,
Issue 4,
1977,
Page 428-430
MARVIN AMSTEY,
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摘要:
Non-Group A or D beta hemolytic streptococci were identified in the vaginas of 5-11% of prenatal patients. More than 97% of organisms so identified have been found to be specifically Group B beta hemolytic streptococci (GB-BHS). The differences may have been related to seasonal changes. These organisms were found in 5% of preabortion patients—none of whom developed any infectious morbidity even though no therapy was used prior to the abortion. Of 100 gynecologic patients undergoing major gynecologic surgery, 17% had preoperative cultures positive for GB-BHS. However, the morbidity (18%) was the same for the culture-positive and culture-negative patients.
ISSN:0029-7844
出版商:OVID
年代:1977
数据来源: OVID
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