ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Soluble fibrin monomer complexes have been determined in approximately 500 obstetric patients by protamine sulfate precipitation, as a test for intravascular coagulation. The incidence of positive fibrin monomer was less than 1% in 139 samples drawn during normal pregnancy. In confirmed abruptio placentae, 84% of samples were positive, but other sources of antepartum bleeding were negative. Positive results were obtained in 24% of samples from patients with a dead fetus, in 19% of patients with preeclampsia, and in 18% with sepsis. In samples drawn from patients between 3 and 48 hours after injection of hypertonic saline for second trimester abortion, 33% were positive but only 3% were positive after administration of prostaglandins. The test for intravascular coagulation is simple and rapidly carried out. The results correlated well with the clinical condition of patients with disseminated intravascular coagulation. However, the test is usually negative in patients with thromboembolic phenomena.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Eighteen patients were given carefully controlled intravenous heparin for thromboembolic disease of pregnancy. Thirteen were treated in later gestation and postpartum, mainly following warfarin therapy. One was treated in early pregnancy and 4 in the postpartum period. Heparin was delivered by constant infusion and dosage regulated by maintaining the thrombin time at 2 to 4 times normal. Therapy was stopped for a few hours before and after delivery so that the thrombin time was normal or nearly normal at birth. Two minor episodes of thrombosis recurred in 1 patient while on warfarin, and significant postpartum bleeding occurred in one other. Substituting heparin for warfarin in late gestation was of value in preventing neonatal bleeding complications.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Urinary estrogen determination have simplified the care of program patients certain metabolic disorders known to adversely affect the terms. This reports demanstrates that erroaeously low values for urinary estrogens may be obtained if colorometric assay methods are used for patiens with congenital hemolycic anemis during an acute hemolytic crisis.This appears tom be due to the interference of the large amounts of urobilin presents in the urine of these patients.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Fetal heart rate (FHR) acceleration have never been fully investigated. These accelerations are responses of the healthy fetus to various stimuli and stresses. Observations and proper evaluation of FHR accelerations patterns will give reassurance of fetal well-being. The fetal activity acceleration determination (FAD) is a method of antepartum evaluation of fetal well-being. The FAD can he used where the oxytocin challenge test is contraindicatcd. The physiologic bases of FHR accelerations are discussed. An attempt has been made to classify the FHR acceleration patterns.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

There were 25-1 cases studied in which two tests of fetal maturity were performed within 72 hours of each other. The two tests were an x-ray fetogram and an amniotic fluid L/S ratio determination. All fetograms were read by one author for the presence of distal femoral epiphysis (DFE). It was assumed that DFE permits estimation of fetal hone maturation and L/S ratio permits estimation of fetal lung maturity. The DFE results gave a 10% false positive rate in predicting a mature L/S ratio (>2.0) and a 38.7% false-negative rate. Of the 21 patients who delivered within 3 days of the performance of the two tests, all neonates did well when there were no visible DFE's hut a mature L/S ratio. There is a significant lack of specificity and sensitivity of the fetogram DFE is in predicting a mature L/S ratio. Since infant lung maturation is a critical factor in predicting neonatal survival, these results suggest that the x-ray DFE is unacceptable as a single maturity test for use in a perinatal center managing complicated obstetric cases.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The records of 517 pregnancies which terminated in the delivery of infants weighing 9 lb or more were reviewed. The obstetric patient most likely to deliver a large birth weight infant was characterized. Toxemia, prolonged labor, and puerperal morbidity occurred with increased frequency. Many of the deliveries were complicated by fetopelvic disproportion with resultant increase in mid forceps deliveries, cesarean sections, and perinatal morbidity. Five of the 517 patients delivering large birth weight infants were known to have diabetes mellitus prior to le pregnancy included in this study. An additional 369 patients were evaluated with intravenous glucose tolerance tests. Thirty-eight (10.3%) of the 369 tested proved to lave diabetic glucose tolerance curves. The likelihood of [hiding maternal diabetes mellitus increased with the infant's birth weight. Multiple regression analysis of other clinical variables failed to predict which patients would prove to have diabetes. Identification of diabetic puerperas requires that glucose tolerance tests be performed in all who deliver large birthweight infants.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Maternal, fetal and umbilical blood glucose, insulin, and human growth hormone (HCH) levels were measured to determine their relation during labor and at delivery. There was a positive correlation between fetal glucose and HGH, as well as between the fetal insulin and HGH values. Higher birthweights were associated with lower umbilical venous HCH and higher insulin levels. Thus, the balance between insulin and growth hormone might be involved in the regulation of fetal growth.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

n order to evaluate the carbohydrate metabolic effects of certain drug therapies used in treating the toxemia syndrome, 75 term pregnant women were studied with two intravenous glucose tolerance tests performed 1 week apart. During the 2-hour tests, both blood glucose and plasma insulin were measured. The women were randomly assigned to three treatment groups, and during the week between the tests they received: a) no drugs (control or C group); b) Diuril®,500 mg/day (D group); or r) Dilantin®, 100 mg,. i.d. (DL group). Each group was of similar age, weight, and gestational age. There were no significant changes in any of the glucose curves. Both drug-treated groups demonstrated insulin changes. In contrast to the C group, the D group -showed an elevation of the plasma insulin values during the second test, and the DL group had a lowering of plasma insulin levels in the second test. Thus, both drugs had minor effects on carbohydrate metabolism during short-term use. However,: i more marked metabolic effect of these drugs must be considered when using them at higher dosages or for a longer duration.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID