ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Data from a total of 74 pregnancies in 42 patients with sick-ling disorders seen at Johns Hopkins Hospital are compared with similar data from other centers. Although risks are still higher than those for women without sickle cell disease, they have diminished significantly from those reported earlier. Prophylactic transfusion therapy may decrease these risks further, but benefits of transfusion are unproved at present. Patients with sickling disorders should receive meticulous individualized treatment until further data are made available.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Eighty-eight primigravidas underwent a roll over test performed according to the method suggested by Gant. A single individual performed the tests, and the results were withheld from the physician taking care of the patient. After delivery, 14 cases were excluded for various reasons, and, of the remaining 74 patients, 27 had negative results. Of these, 19 (70.4%) results were true negative and 8 (29.6%) were false negative. Forty-seven patients had a positive roll over test, of whom 35 (74.5%) did not develop hypertension in pregnancy and 12 (25.5%) did. The authors' results did not confirm the reliable predictive ability of the roll over test as reported by Gant and other investigators.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

The relationship between maternal age and the frequency of dysfunctional labor patterns was assessed retrospectively in a population of 6248 gravid women. A significant correlation between age and protraction disorders was observed in nulliparas. This could not be accounted for by patterns of anesthetic use, and it is speculated that a decrease in myometrial efficiency may accompany aging during the reproductive years.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Fetal movements (FM) in utero are an expression of fetal well-being, and the importance of assessing these movements has been shown in cases of chronic fetal distress. The diurnal variations were studied in 2 groups of high-risk pregnant women who assessed FM by subjective perception. The patients in the first group assessed FM before and after meals. The majority (86%) reported no significant difference in fetal activity before and after meals; the remaining 14% noted a constant decrease after meals. Of the second group, which assessed FM 3 times daily, 82% discerned no significant differences and 18% showed significant diurnal variations. It is concluded that assessment of FM is not necessarily dependent on a strict timetable.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Perinatal morbidity and mortality are known to be higher for the macrosomic neonate whose birth weight is 4500 g or more, compared with that of appropriate-weight term-size neonates. In a retrospective study comparing 287 macrosomic neonates with 284 appropriate-weight term-size neonates, we found that macrosomia occurred in 1.3% of our annual deliveries, with a male-to-female ratio of 2.3:1. Factors that occurred significantly more frequently in the mothers of macrosomic infants were maternal obesity, multiparity, diabetes mellitus, and previous delivery of an infant heavier than 4000 g. During the intrapartum period the incidence of labor augmentation by oxytocin, shoulder dystocia, and cesarean section was significantly greater in fetal macrosomia. Most significantly, this study revealed that macrosomic fetuses do not experience greater fetal distress in biophysically monitored labor than appropriate-weight term-size fetuses. Twenty-nine (10%) of the macrosomic infants required admission to the neonatal intensive care unit (NICU) compared to 9 (3%) of the control patients (P< 0.01). This excess neonatal morbidity in the macrosomic neonates was predominantly caused by the delivery process.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

In order to investigate the responses of insulin and glucagon to the same glycemic stimulus in late normal pregnancy and post partum, appropriate quantities of glucose were infused intravenously in 7 normal women at both stages. In this manner similar glucose curves were obtained in the 2 conditions. The insulin response to glucose infusion was increased 3.8 times in late pregnancy, whereas the suppression of glucagon was similar in late pregnancy and post partum. The results confirm that the β-cell sensitivity to a glycemic stimulus is substantially increased in normal late pregnancy, but the α-cell sensitivity to a glycemic stimulus is unaffected by pregnancy.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Maternal plasma prolactin, estradiol-17β, and free estriol levels were estimated in 118 normal pregnancies and in 90 patients with preeclampsia at 35 to 40 weeks' gestation. In the preeclamptic patients, the prolactin values were similar to those of normal pregnancy; the levels were not affected by the severity of disease. At 37 to 38 weeks' gestation the maternal plasma free estriol levels correlated positively with the prolactin levels in preeclampsia (r= .313;P< .05;N= 64). No correlation was found between the levels of prolactin and estradiol-17β or between prolactin and urinary estrogen. Fetal distress was related to decreased plasma estradiol levels, but this was not reflected in the prolactin concentrations. The results of the present study show that the estimation of plasma prolactin level is of no clinical significance in patients with preeclampsia.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

Hyperparathyroidism during pregnancy is associated with greatly increased perinatal morbidity and mortality. Severe neonatal hypocalcemia and tetany is a particularly serious complication. Surgical removal of the abnormal parathyroid glands is currently recommended during pregnancy in view of the severity of the complications in the untreated patients and the favorable results in patients who have had surgery during pregnancy. Two patients are reported in whom surgery during pregnancy could not be performed. They were treated with oral phosphate, which successfully decreased serum calcium; their infants remained normocalcemic throughout the neonatal period. It is suggested that in selected cases medical treatment with oral phosphate can be an effective therapeutic alternative and surgery may be postponed until after delivery.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID

摘要:

The present study was designed to estimate the prognosis for patients admitted with threatened abortion on the basis of assays of serum estradiol (E2) and progesterone (P) and the demonstration of fetal heart movements (FHM) by ultrasound scanning. Of the 97 patients included in the study, 35% (with 95% confidence limits 25 to 45%) aborted spontaneously. Of the patients with normal serum E2and P levels, 88% (74 to 96%) and 91% (79 to 98%), respectively, continued to term, whereas 52% (39 to 66%) and 58% (44 to 72%), respectively, with pathologic levels aborted. Ultrasound scanning for FHM exhibited the greatest diagnostic accuracy: 92% of the patients (83 to 97%) with FHM at the first scan carried to term, and 91% (75 to 98%) without FHM aborted. After 9 weeks' gestation, the recording of FHM, if any, was reliable in 100% of the cases. It is concluded that ultrasound scanning with determination of FHM is of greater prognostic value than hormone assays in patients with threatened abortion.

ISSN:0029-7844    

出版商:OVID    

年代:1980

数据来源: OVID