摘要:

The first 21 cases recorded in the Registry for Endometrial Carcinoma in Young Women Taking Oral Contraceptive Agents are reported. We have found no other such cases in the literature, and indeed several authors have stated that these agents, because of their predominantly progestational action, would be expected to be protective against this disease. In 8 of the 21 patients, factors were present which militated against a close relation between oral contraceptives and carcinoma, and 5 of these S patients had taken only or predominantly combined agents. On the other hand, 11 of the remaining 13 patients took sequential agents, a ratio directly opposite that of the usage of combined and sequential agents in the American population. The possible reasons for the excess of sequential agents, chiefly Oracon, arc discussed, and directions for future study are suggested.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

There were 289 radical hysterectomies performed at Roswell Park Memorial Institute for Stage IB, IIA, and recurrent cervical cancer from 19S7 to 1967. The prognostic significance of cervical lesion size, pelvic node mctastases, and type of radical hysterectomy have been evaluated. Excellent 5-year survival rates for women with Stage IB cervical carcinoma were associated with cervical lesions measuring less than 3 cm and resected pelvic lymph nodes which did not contain metastatic cancer. In addition, 31% of women with recurrent cervical cancer treated by radical hysterectomy survived 5 years without recurrence.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Leiomyomatosis peritonealis disseminata (LPD) is a rare clinical entity. Widespread subperitoneal nodules of apparent smooth muscle arc found in patients who are pregnant or have recently been so. This clinical appearance together with mitotic figures found in frozen sections suggests malignancy. We believe, in contrast, that LPD is a benign reparative process in which fibroblasts replace subperitoneal decidua.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Ureteral obstruction following radiotherapy for cervical cancer is most often due to recurrent tumor. However, in a few patients ureteral stricture is secondary to radiation damage. surgical treatment of this obstruction requires special consideration since many procedures for urinary diversion may be contraindicated in an irradiated pelvis. Ileal substitution (uretero ileoncocystostomy) preserves renal function without resorting to external diversion of urine.A discussion of the method together with a report of 6 patients treated in this manner is presented. Results were excellent, with followup ranging from 1 1/2 to 4 years. A brief history of irradiation damage to the ureter and the use of small bowel as substitute ureter is discussed. Patient acceptance of this surgical approach was gratifying.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The hospital records of 24 patients over 75 years of age who had 25 surgical procedures in treatment for invasive gynecologic cancer were viewed. The patients were matched with control patients age 55 or less who had the same operative procedure and intraoperative and postoperative complications compared. The incidence of wound complications was higher in the elderly patients, while the other complications were lower. Age should not be an absolute contraindication to surgery for gynecologic malignancy if the prospects of cure are good.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Povidone-iodine solution (Betadine) at concentrations of 0.167% (v/v) reduced the end-point titers of Strain E.M. herpesvirus, type 2, by more than 99.99%. Even at concentrations of 0.0167% (v/v), povidone-iodine solution reduced the titers by 92%. The iodine solution, per se, had no effect on cultured human fibroblasts in concentrations of 1.67% (v/v).

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

Abdominal wound disruption occurred in 6 cases in a series of 2500 consecutive abdominal laparotomies. A prospective study of 900 laparotomies utilizing polyglycolic acid suture material and the Smead-Jones closure technic was carried out over a period of 1 year with a reduction in the incidence of wound disruption from 0.4 to 0.1%. Etiologic factors placing patients in a high-risk category for disruption are identified, and specific prophylactic measures are discussed. Prevention of catastrophic disruption is advocated because of its high mortality rate, averaging 20%.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The empty sella syndrome is defined anatomically and radiological!). A case report of an amenorrheic patient who was diagnosed as having the primary empty sella syndrome is presented. Ils pathogenesis, clinical profile, and endocrine relationships are discussed. Specific reference is directed toward the capability of the empty sella syndrome to produce pituitary impairment and possibly amenorrhea.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

In order to assess the action of prolactin on the puerperal pituitary-ovarian resistance to physiologic stimulation, a study was conducted in 27 women divided into three croups. Group 1:9 postpartum women who did not wish to breastfeed their infants and received 2.5 mg bromocriptin (CB 154) twice daily for 14 days starting immediately after delivery: Group II: 9 normally lactating mothers; and Group III: 9 women with hyperprolactinemia associated with amenorrhea. The three groups underwent stimulation with LHRH and Pergonal 500. Results indicate lack of prolactin dependence in the pituitary-ovarian resistance of the puerperium. The possible mechanisms involved in the anovulatory period of lactation arc discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID

摘要:

The peripheral levels of pregnenolone (δ3-p), 17-hydroxypregnenolone (17-δ3-P), progesterone (P), 17-hydroxyprogestcrone (17-P), testosterone (T), 5α -dihydrotestosterone (DHT), androstencdione (A), dehydroepiandrostcrone (DHEA), its sulfalc (DHEA-S), estronc (E2), estradiol-17β (E2), and cortisol (F) were measured prior to and 11/2 and 9 months after removal of a right adrenal “compact cell” adenoma in an amenorrheic patient with a virilizing adrenal adenoma, under the following conditions: 1) control for 2 days, 2) dexamethasonc, 0.5 mg, every 6 hours for 2 days, and 3) dexamclhasonc, 2 mg, every 6 hours for 2 days. Except for E2, E2, and F, the control levels of ail steroids measured were elevated, markedly so for δ3-P, 17-δ3-P, DHEA, A, and DHEA-S. Dexamethasonc treatment had no detectable effect on the steroid levels. Following removal of the adrenal adenoma, the levels of all steroids returned to normal. The patient became cumenorrheic, with marked improvement of her hirsutism and virilization.

ISSN:0029-7844    

出版商:OVID    

年代:1975

数据来源: OVID