摘要:

The revolutionary changes in the mores and practices of adolescent sexuality have not as yet resulted in a significant increase in the rates of cervical cancer precursors in a study of 29,600 young women under age 21. The study represents women from families of low socioeconomic status. Over a 21-year period no case of carcinoma in situ nor of invasive cervix cancer occurred. The dysplasia rate was low (0.9/1000), and when prerevolutionary and revolutionary periods were compared, there were no significant differences in the rates. Cryocautery was successful in ablating dysplasia, as was follow-up without treatment. An attempt will be made to continue to monitor these young women of the sexual revolution since the effects of their past and current participation might not be discernible for years to come.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

A total of 610 radical hysterectomies with bilateral pelvic lymphadenectomy were performed at the Mayo Clinic in the 20-year period from 1956 through 1975. This operative procedure was the primary therapy in 74% of the patients, the others having had previous pelvic irradiation. Operative morbidity, postoperative complications, lymph node involvement, and overall survival were analyzed.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

To determine if preoperative irradiation should be abandoned in favor of post-hysterectomy irradiation, 65 cases of stage I endometrial carcinoma were analyzed. When no residual tumor or no myometrial invasion was found in the irradiated uterus (38 cases), a 5-year cure rate of 97.3% was obtained. When residual tumor or myometrial invasion was found, there was a 5-year cure rate of 100% in grades 1 and 2 (7 cases) but only a 20% cure rate in grade 3 lesions (5 cases). On the basis of these data there appears to be no reason to abandon preoperative irradiation in stage 1 cases. More extensive irradiation and surgery should be considered, however, in grade 3 lesions invading the myometrium.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

Three hundred twenty-seven patients with ovarian carcinoma were compared with matched controls to determine the association of parity and marital status with the development of ovarian cancer. Nulliparous women were found to have 2.31 times the risk of developing ovarian cancer as parous women. Unmarried women had 3 times the risk of developing ovarian cancer, but marital status was not established as a variable independent of parity. Almost 8% of patients with ovarian carcinoma had had hysterectomies when they were over 40 years of age. This study indicates that parity is an important consideration when determining whether a patient is at high risk for the development of ovarian carcinoma. Other epidemiologic variables are discussed in an effort to facilitate the judicious selection of patients for elective oophorectomy at the time of hysterectomy.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

In the course of their practice 2 gynecologists have conducted a program of screening for breast cancer in 1538 patients ages 35–49 years and on 1102 patients ages 50 or older. The screening protocol of breast examinations, thermography, and selective mammography is described. Twenty-four (9/1000) breast cancers were found, 12 in each age group. Eight of these (3/1000) were clinically occult (6 in the younger age group, 4/1000) and were detected by abnormal thermograms followed by mammography. Of the 12 cancers in the 35–49-year-old age group, 6 were discovered at the first screening, and the other 6 by thermographic changes at intervals of 6–24 months. Thermographic screening is more accurate than breast examination alone, but less accurate than if mammography is included. However, since routine annual use of the latter in younger women still raises concerns about x-ray dosage, thermography is a valuable adjunct to physical examination alone. When it is abnormal, mammography is indicated. The 3 complementary methods can reveal about 9 of 10 preclinical cancers in young women.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

Twelve patients with vaginal intraepithelial neoplasia received topical therapy with 5% 5-fluorouracil cream. Six patients had carcinoma in situ, 5 had moderate dysplasia, and 1 had mild dysplasia. Five patients responded to 1 treatment course. Six patients required 2, and 1 patient required 3 courses of therapy to respond. Three patients developed recurrent vaginal intraepithelial neoplasia 11–16 months after therapy and were retreated with topical 5-fluorouracil. Vaginal irritation occurred in all patients but was limited to the duration of the treatment course.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

Twelve patients thought to have gynecologic tumors subsequently were found to have lymphoma or leukemia. Eleven tumors involved the genital organs; one involved the retroperitoneal pelvic lymph nodes. A lymphoma originated in the genital tract in 7 patients, and secondary involvement occurred in 2 patients. One patient with a previously treated lymphoma and 1 with leukemia in remission developed ovarian tumors as the first sign of relapse. The difficulty in diagnosis, need for appropriate treatment, and prognostic importance of the genital organs affected are discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

One hundred seventeen women were reexamined within 6 months after presenting with genital herpes. Swabs for virus isolation were taken from the cervix whether or not lesions were observed. Herpesvirus type II was isolated from 30 of 67 patients with recurrent disease, but also from 5 of 50 women during periods when there were no signs or symptoms of illness. The epidemiologic importance of virus shedding from asymptomatic women is discussed.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

The ovarian remnant syndrome is one of the least recognized and least discussed complications of oophorectomy. The most common presentation is pelvic pain with a pelvic mass. To prevent the condition, the ureters should be mobilized and laterally displaced during oophorectomy, and the pelvic side wall and cul-de-sac peritoneum should be excised when the ovary is adherent to these areas as a result of endometriosis or inflammation.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID

摘要:

Gracilis musculocutaneous flaps are useful in reconstruction of many crippling pelvic defects. They are especially beneficial for vaginal reconstruction at the time of pelvic exenteration. Twenty patients having vaginal reconstruction with musculocutaneous flaps arc presented. Nineteen (95%) have vaginas adequate for sexual function.

ISSN:0029-7844    

出版商:OVID    

年代:1979

数据来源: OVID