11. |
Chemoradiotherapy + oesophagectomy prolongs survival |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 12-12
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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12. |
Extended-release oxybutynin an effective option in overactive bladder |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 13-14
Charles Bankhead,
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摘要:
Antimuscarinic agents have become standard pharmacological therapy for urinary incontinence. However, a substantial proportion of patients find the anticholinergic adverse effects, particularly dry mouth, difficult to tolerate. Recently, extended-release (ER) formulations of oxybutynin and tolerodine have been developed with the objectives of permitting once-daily dosing and reducing anticholinergic side effects without adversely affecting the efficacy of the compounds. At the WHO 2nd International Consultation on Incontinence (ICI) [Paris, France; July 2001] results from two studies showed oxybutynin ER ['Ditropan XL'] to be effective and well tolerated in patients with overactive bladder secondary to multiple sclerosis or spinal cord injury. Additionally, in a preliminary clinical comparison, changes in gastric pH altered the functionality of tolterodine ER ['Detrol LA'] but not oxybutynin ER. Specifically, a rise in pH resulted in a 'dumping phenomenon', or accelerated release of tolerodine soon after administration.
ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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13. |
News in brief ... |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 14-14
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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14. |
Nitazoxanide effective against enteric protozoal infection |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 15-15
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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15. |
News in brief ... |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 17-17
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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16. |
Tackling resistance in HIV infection |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 18-19
Carmen Innes,
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摘要:
Resistance to antiretrovirals continues to be a major problem for patients with HIV infection. A number of studies presented recently at the 1st International AIDS Society Conference on HIV Pathogenesis and Treatment [Buenos Aires, Argentina; July 2001] dealt with this complex issue. In the first study, researchers evaluated genotypic resistance to lopinavir/ritonavir and nelfinavir in previously untreated patients with HIV infection, and found higher levels of resistance to nelfinavir than to lopinavir/ritonavir. Another team of investigators noted that non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance mutations appear to persist in several patients after withdrawal of this class of drugs. Two additional studies reported that, compared with standard of care, phenotypic or genotypic testing did not significantly improve response to further therapy in patients failing a protease inhibitor-based regimen.
ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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17. |
News in brief ... |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 19-19
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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18. |
Haemostatic disorders with 'Elohes': 9 cases in France |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 20-20
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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19. |
Severe cutaneous reaction to imatinib mesylate reported |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 21-21
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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20. |
Regulatory news from the US |
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Inpharma Weekly,
Volume &NA;,
Issue 1303,
2001,
Page 22-22
&NA;,
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ISSN:1173-8324
出版商:ADIS
年代:2001
数据来源: ADIS
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