| 11. |
Imatinib mesylate: best first-line pharmacotherapy for CML |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 13-13
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 12. |
Supplementation with folic acid plus ferrous fumarate during pregnancy reduces the incidence of low birthweight in rural Nepal, |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 14-14
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 13. |
Daclizumab ameliorates acute ulcerative colitis |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 15-15
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 14. |
Valproate semisodium accelerates improvement of psychosis |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 16-16
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 15. |
Testosterone undecanoate: effective contraceptive for Chinese men? |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 17-17
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 16. |
Citalopram lowers serum leptin levels in patients with premature ejaculation, |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 18-18
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 17. |
Reduced potential for hepatotoxicity with newer thiazolidinediones? |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 19-20
AJ Scheen,
Preview
|
|
摘要:
Insulin resistance, characteristic of type 2 diabetes mellitus, contributes to the progression of atherosclerosis, and is at least partly responsible for the poor cardiovascular prognosis in patients with diabetes. By improving insulin sensitivity, thiazolidinediones ['glitazones'] promised an exciting new approach for type 2 diabetes. However, the severe hepatotoxicity associated with troglitazone, the first thiazolidinedione to be approved, threatened to minimise the clinical usefulness of this class of drugs. Troglitazone markedly elevated ALT levels during clinical trials and has been associated with severe and sometimes fatal hepatotoxicity. However, rosiglitazone and pioglitazone have only been associated with isolated episodes of hepatic dysfunction. A review of the literature indicates that hepatotoxicity appears to be associated with specific properties of troglitazone, rather than the thiazolidinedione ring. Thus, newer thiazolidinediones appear to have minimal potential to cause hepatotoxicity and, when used judiciously, offer an alternate approach to the management of type 2 diabetes.
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 18. |
US FDA announces initiatives to improve patient safety |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 21-21
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 19. |
Viragen's natural human interferon-α product has been approved in South Africa |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 22-22
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
| 20. |
Product Introductions |
| |
Inpharma Weekly,
Volume &NA;,
Issue 1379,
2003,
Page 23-23
&NA;,
Preview
|
|
ISSN:1173-8324
出版商:ADIS
年代:2003
数据来源: ADIS
|
首页
