ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

摘要:

Preliminary work using a mouse retrovirus provides hope that retroviruses can be targeted to specific cells. If the approach proves to be effective, it could open up new possibilities for gene therapy, including systemic administration of certain genes. At present, retrovirus-mediated gene therapy is unable to discriminate between cells, as they use the ubiquitous phosphate transporter receptor for cell entry. Thus, the genes have to be injected into specific tissues or administered by inhalation. The feasibility of the new targeted approach was discussed at the ICM meeting ‘Investing in Gene Therapy’ [London, UK; January 1995].

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

摘要:

Irinotecan, a camptothecin analogue, has shown activity in patients with colorectal cancer, including those who have relapsed following treatment with fluorouracil. This is of significant interest as there is currently no second-line drug approved for use in this situation. Final results of a phase II trial in this patient group were reported at a symposium sponsored by Rhône-Poulenc Rorer at the 5th International Conference on Anticancer Chemotherapy [Paris, France; February 1995].

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1995

数据来源: ADIS