ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

摘要:

Are the newer antidepressant drugs really new or merely improvements on the old? After all, their efficacy is similar to the old, they are still required to be given over the long term, their mechanism of action is still dependent on neurotransmitter availability, and all still have a delayed onset of action, according to Dr Bill Lyndon from the University of Sydney, Australia, speaking at the International Congress on Depressive Disorders [Melbourne, Australia; July 1999].

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

摘要:

Acute heart failure is a haemodynamic disease which responds to haemodynamic intervention. This is in contrast to chronic heart failure, a neurohormonal disease requiring neurohormonal intervention. Current therapy for acute heart failure includes IV diuretics, vasodilators and positive inotropes. Speaking at the 3rd International Meeting on Heart Failure [Gothenburg, Sweden; June 1999], Dr M Packer from Columbia University, New York, US, said that the goals for the treatment of acute heart failure should be the same as those for chronic heart failure, i.e. to improve symptoms and decrease the risk of death and worsening heart failure. Positive inotropic agents are deleterious long term; however, they have beneficial effects in short term treatment. New strategies in the development of positive inotropic agents include phosphodiesterase inhibitors, &agr;-blockers and calcium sensitisers. One promising new calcium sensitiser under discussion at the meeting was levosimendan.

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

摘要:

Building on results reported a year ago*, an inhaled formulation of human insulin continues to produce evidence that it represents a viable alternative to conventional injectable insulin for the treatment of diabetes mellitus. In patients with type 2 diabetes mellitus who are poorly controlled on oral antihyperglycaemic therapy, the addition of inhaled insulin results in a significant improvement in glycaemic control compared with oral therapy alone. Adding inhaled insulin to oral antidiabetic agents is associated with an increase in the incidence of hypoglycaemia, but most patients find the episodes tolerable. An unrelated study showed a significant preference for inhaledvsinjectable insulin among patients with diabetes mellitus. The preference findings come from a study reported last year showing equivalence of inhaled insulin to injectable insulin. The latest findings were reported at the 59th Annual Meeting of the American Diabetes Association meeting [San Diego, US; June 1999].

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1999

数据来源: ADIS