ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

摘要:

Research chemists from most of the major pharmaceutical companies gathered at the 13th International Symposium on Medicinal Chemistry [Paris, France; September 1994] to compare notes on novel drug design and development. Particular interest was shown in the endothelin receptor antagonists, a class of drugs that represents a major avenue of research in the fields of hypertension, stroke, congestive heart failure and acute renal failure.

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

摘要:

The validity of tackling osteoporosis with parathyroid hormone (PTH) and related analogues is now under investigation. Recent research shows that human PTH can reverse bone loss in osteoporosis that has developed in patients treated for endometriosis. And a further study has tested a PTH-related protein (PTH-rp) analogue in symptomatic, postmenopausal women with osteoporosis. More complex regimens have been tested in animal models, where the addition of bone-resorption inhibitors has further increased bone calcium levels. These findings, together with details of a new angle for studying hormone-receptor interactions, were presented at the 16th Annual Meeting of the American Society for Bone and Mineral Research [Kansas City, US; September 1994].

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1994

数据来源: ADIS