ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

摘要:

For the first time in 25 years, anaesthetists have a new local anaesthetic to consider when choosing the optimal treatment for their patients. It was clear at the 11th World Congress of Anaesthesiologists [Sydney, Australia; April 1996] that greater emphasis is now being placed on the ability to fine-tune surgical anaesthesia and acute pain management to individual patient needs. The launch of ropivacaine [Naropin®; Astra] is a step in the right direction. Compared with bupivacaine, the new agent has an improved tolerability profile, allowing higher doses to be used when profound muscle relaxation is required during surgery. Regarding acute pain management, the greater difference between the sensory and motor effects of low-dose ropivacaine, compared with bupivacaine, allows effective analgesia with a more rapid recovery to full patient mobilisation.

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

摘要:

Expectations are high for antagonists of tumour necrosis factor-&agr; (TNF-&agr;) as therapy for rheumatoid arthritis. Dr T Maini from the Kennedy Institute of Rheumatology, who is a leading researcher in this field, singled out TNF-&agr; as one of the most important targets in current rheumatology research. Both biological and chemical approaches to inhibiting this factor are under development. Of particular note are the results from clinical studies with Centocor's anti-TNF-&agr; monoclonal antibody (mAb) cenTNF [cA2; phase II]. This antibody produced significant responses in 90% of patients 4 weeks after treatment administration. In an interview withInpharma®, Dr Maini discussed cenTNF and other anti-TNF-&agr; strategies featured at the 8th Asia-Pacific League of Associations for Rheumatology Congress [Melbourne, Australia; April 1996].

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS

ISSN:1173-8324    

出版商:ADIS    

年代:1996

数据来源: ADIS